엽산 관련 영양 결핍성 탈모
F 효과 연구에 따르면 이 용도에 효과가 있을 가능성은 낮은 것으로 나타납니다.총 4,429명의 참여자를 대상으로 한 11건의 연구에 근거합니다. 연구 결과는 혼재되어 있습니다.
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F
결론
The evidence linking folate supplementation to hair regrowth is limited and mixed — folate deficiency may contribute to hair loss in some cases, but supplementation is not well-supported as a general hair loss remedy.
- Results are mixed across 11 studies, with no clear consensus on folate's role in hair loss
- No randomized controlled trials have specifically tested folate supplementation for hair regrowth
- Folate deficiency may be more relevant when caused by medications (e.g., methotrexate) rather than diet
- Blood testing for folate levels may help determine if supplementation is appropriate
Key Study Findings
In Vitro
7-Hydroxycannabidiol and 7-carboxycannabidiol induced cytotoxicity via apoptosis and endoplasmic reticulum stress in human hepatic cells.
Dose: None
vs: Untreated hepatic cells
Outcome: Cytotoxicity via apoptosis and ER stress
효과: None
None
대상 집단: Primary human hepatocytes and HepG2 cells
Review
Safety First: A Comprehensive Review of Nutritional Supplements for Hair Loss in Breast Cancer Patients.
Dose: None
vs: Placebo
효과: None
None
Review
Medical Marijuana and Treatment Personalization: The Role of Genetics and Epigenetics in Response to THC …
Dose: None
vs: None
Outcome: None
효과: None
None
대상 집단: Review of pharmacogenomics of THC and CBD
In Vitro
2 weeks
Quality and safety of hemp meal as a protein supplement for nonlactating dairy cows.
Dose: 10.2% d
vs: None
Outcome: glycemic control
효과: None
None
대상 집단: Cows
Case-control
n=973
Micronutrient Deficiencies and Digital Computerized Phototrichogram Analysis in Telogen Effluvium: a Retrospective Correlation Study in …
Dose: None
vs: Placebo
효과: r=0.417 (HGB and AHR in females)
p=0.008
retrospective cohort study
n=3028
Telogen effluvium in daily practice: Patient characteristics, laboratory parameters, and treatment modalities of 3028 patients …
Dose: standard replacement doses
vs: Placebo
효과: vitamin D deficient: 72.2%; B12 deficient: 30.7%; iron deficiency anemia: 6.2%
None
Key Statistics
11
연구
4166
참여자
↔
Mixed
F
등급
Referenced Papers
Nutrients
2025
2 인용
Archives of toxicology
2025
1 인용
Genes
2025
1 인용
Journal of dairy …
2023
8 인용
Dermatology practical & …
2023
4 인용
Journal of cosmetic …
2022
22 인용
Medical cannabis and …
2018
158 인용
American journal of …
2017
104 인용
Journal of drugs …
2016
56 인용
Clinical and experimental …
2009
34 인용
Dermatologic clinics
1993
38 인용
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
일반적으로 사용되는 용량
- general:
- 400 mcg DFE/day
상한량: 1,000 mcg/day (synthetic folic acid)
연구에서 사용된 용량
| 용량 | 기간 | 효과 | N |
|---|---|---|---|
| None | -- | Negative | -- |
| None | -- | Mixed | -- |
| None | -- | Mixed | -- |
| 10.2% d | 2 weeks | Mixed | -- |
| None | -- | Positive | 973 |
| standard replacement doses | -- | Neutral | 3028 |
| None | -- | Positive | -- |
| None | -- | Negative | -- |
권장 복용 시간: With meals for better absorption
Safety & Side Effects
보고된 부작용
- ⚠ Generally well tolerated
- ⚠ May mask vitamin B12 deficiency symptoms at high doses
- ⚠ Rare: abdominal cramps, insomnia
알려진 상호작용
- ● Methotrexate (folate antagonist; consult physician)
- ● Anticonvulsants (phenytoin, carbamazepine) may reduce folate levels
- ● Sulfasalazine (reduces folate absorption)
일일 최대 섭취 허용량: 1,000 mcg/day (synthetic folic acid)
건강기능식품을 복용하기 전에 반드시 의료 전문가와 상담하십시오.
Frequently Asked Questions
Does 엽산 help with 영양 결핍성 탈모?
Based on 11 studies with 4,166 participants, there is insufficient evidence at this time that 엽산 may support 영양 결핍성 탈모 management. Our evidence grade is F (Evidence Against).
How much 엽산 should I take for 영양 결핍성 탈모?
Studies have used various dosages. A commonly studied range is 400 mcg DFE/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of 엽산?
Reported side effects may include Generally well tolerated, May mask vitamin B12 deficiency symptoms at high doses, Rare: abdominal cramps, insomnia. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for 엽산 and 영양 결핍성 탈모?
We rate the evidence as Grade F (Evidence Against). This rating is based on 11 peer-reviewed studies with 4,166 total participants. The overall direction of effect is mixed.
Related Evidence
References
- [1] Andrea Sechi et al.. Nutrients. 2025. Safety First: A Comprehensive Review of Nutritional Supplements for Hair Loss in Breast Cancer Patients. doi:10.3390/nu17091451 PubMed
- [2] Yuxi Li et al.. Arch Toxicol. 2025. 7-Hydroxycannabidiol and 7-carboxycannabidiol induced cytotoxicity via apoptosis and endoplasmic reticulum stress in human hepatic cells. doi:10.1007/s00204-025-04001-7 PubMed
- [3] Małgorzata Kalak et al.. Genes (Basel). 2025. Medical Marijuana and Treatment Personalization: The Role of Genetics and Epigenetics in Response to THC and CBD. doi:10.3390/genes16121487 PubMed
- [4] F Addo et al.. J Dairy Sci. 2023. Quality and safety of hemp meal as a protein supplement for nonlactating dairy cows. doi:10.3168/jds.2023-23222 PubMed
- [5] Hakan Arslan et al.. Dermatol Pract Concept. 2023. Micronutrient Deficiencies and Digital Computerized Phototrichogram Analysis in Telogen Effluvium: a Retrospective Correlation Study in a Tertiary Medical Center. doi:10.5826/dpc.1303a202 PubMed
- [6] Ahu Yorulmaz et al.. J Cosmet Dermatol. 2022. Telogen effluvium in daily practice: Patient characteristics, laboratory parameters, and treatment modalities of 3028 patients with telogen effluvium. doi:10.1111/jocd.14413 PubMed
- [7] Arno Hazekamp. Med Cannabis Cannabinoids. 2018. The Trouble with CBD Oil. doi:10.1159/000489287 PubMed
- [8] Jordan M Thompson et al.. Am J Clin Dermatol. 2017. The Role of Micronutrients in Alopecia Areata: A Review. doi:10.1007/s40257-017-0285-x PubMed
- [9] Evelyn J Cheung et al.. J Drugs Dermatol. 2016. Vitamin and Mineral Deficiencies in Patients With Telogen Effluvium: A Retrospective Cross-Sectional Study. PubMed
- [10] C Durusoy et al.. Clin Exp Dermatol. 2009. The role of psychological factors and serum zinc, folate and vitamin B12 levels in the aetiology of trichodynia: a case-control … doi:10.1111/j.1365-2230.2008.03165.x PubMed
- [11] D H Rushton. Dermatol Clin. 1993. Management of hair loss in women. PubMed
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