Фолат для Выпадение волос при дефиците питательных веществ

F Эффект Исследования показывают, что данный способ применения, вероятно, неэффективен.

На основе 11 исследований с участием 4,429 участников. Результаты исследований неоднозначны.

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Итог

The evidence linking folate supplementation to hair regrowth is limited and mixed — folate deficiency may contribute to hair loss in some cases, but supplementation is not well-supported as a general hair loss remedy.

Results are mixed across 11 studies, with no clear consensus on folate's role in hair loss
No randomized controlled trials have specifically tested folate supplementation for hair regrowth
Folate deficiency may be more relevant when caused by medications (e.g., methotrexate) rather than diet
Blood testing for folate levels may help determine if supplementation is appropriate

Key Study Findings

In Vitro

7-Hydroxycannabidiol and 7-carboxycannabidiol induced cytotoxicity via apoptosis and endoplasmic reticulum stress in human hepatic cells.

Dose: None или: Untreated hepatic cells Outcome: Cytotoxicity via apoptosis and ER stress Эффект: None None

Популяция: Primary human hepatocytes and HepG2 cells

Review

Safety First: A Comprehensive Review of Nutritional Supplements for Hair Loss in Breast Cancer Patients.

Dose: None или: Placebo Эффект: None None

Review

Medical Marijuana and Treatment Personalization: The Role of Genetics and Epigenetics in Response to THC …

Dose: None или: None Outcome: None Эффект: None None

Популяция: Review of pharmacogenomics of THC and CBD

In Vitro 2 weeks

Quality and safety of hemp meal as a protein supplement for nonlactating dairy cows.

Dose: 10.2% d или: None Outcome: glycemic control Эффект: None None

Популяция: Cows

Case-control n=973

Micronutrient Deficiencies and Digital Computerized Phototrichogram Analysis in Telogen Effluvium: a Retrospective Correlation Study in …

Dose: None или: Placebo Эффект: r=0.417 (HGB and AHR in females) p=0.008

retrospective cohort study n=3028

Telogen effluvium in daily practice: Patient characteristics, laboratory parameters, and treatment modalities of 3028 patients …

Dose: standard replacement doses или: Placebo Эффект: vitamin D deficient: 72.2%; B12 deficient: 30.7%; iron deficiency anemia: 6.2% None

Key Statistics

Исследования

4166

Участники

↔

Mixed

Оценка

Referenced Papers

Safety First: A Comprehensive Review of Nutritional Supplements for Hair Loss in Breast Cancer Patients. Review

Nutrients 2025 2 цитирований

7-Hydroxycannabidiol and 7-carboxycannabidiol induced cytotoxicity via apoptosis and endoplasmic reticulum stress in human hepatic cells. Other

Archives of toxicology 2025 1 цитирований

Medical Marijuana and Treatment Personalization: The Role of Genetics and Epigenetics in Response to THC and CBD. Review

Genes 2025 1 цитирований

Quality and safety of hemp meal as a protein supplement for nonlactating dairy cows. Other

Journal of dairy … 2023 8 цитирований

Micronutrient Deficiencies and Digital Computerized Phototrichogram Analysis in Telogen Effluvium: a Retrospective Correlation Study in a Tertiary Medical Center. Other

Dermatology practical & … 2023 4 цитирований

Telogen effluvium in daily practice: Patient characteristics, laboratory parameters, and treatment modalities of 3028 patients with telogen effluvium. Other

Journal of cosmetic … 2022 22 цитирований

The Trouble with CBD Oil. Other

Medical cannabis and … 2018 158 цитирований

The Role of Micronutrients in Alopecia Areata: A Review. Review

American journal of … 2017 104 цитирований

Vitamin and Mineral Deficiencies in Patients With Telogen Effluvium: A Retrospective Cross-Sectional Study. Other

Journal of drugs … 2016 56 цитирований

The role of psychological factors and serum zinc, folate and vitamin B12 levels in the aetiology of trichodynia: a case-control … Other

Clinical and experimental … 2009 34 цитирований

Management of hair loss in women. Review

Dermatologic clinics 1993 38 цитирований

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Часто используемые дозировки

general:: 400 mcg DFE/day

Верхний предел: 1,000 mcg/day (synthetic folic acid)

Дозировки, изученные в исследованиях

Дозировка	Длительность	Эффект	N
None	--	Negative	--
None	--	Mixed	--
None	--	Mixed	--
10.2% d	2 weeks	Mixed	--
None	--	Positive	973
standard replacement doses	--	Neutral	3028
None	--	Positive	--
None	--	Negative	--

Лучшее время приёма: With meals for better absorption

Safety & Side Effects

Зарегистрированные побочные эффекты

⚠ Generally well tolerated
⚠ May mask vitamin B12 deficiency symptoms at high doses
⚠ Rare: abdominal cramps, insomnia

Известные взаимодействия

● Methotrexate (folate antagonist; consult physician)
● Anticonvulsants (phenytoin, carbamazepine) may reduce folate levels
● Sulfasalazine (reduces folate absorption)

Допустимый верхний уровень потребления: 1,000 mcg/day (synthetic folic acid)

Всегда консультируйтесь с врачом перед началом приёма любых добавок.Всегда консультируйтесь с лечащим врачом перед началом приёма любой добавки.

Frequently Asked Questions

Does Фолат help with Выпадение волос при дефиците питательных веществ?

Based on 11 studies with 4,166 participants, there is insufficient evidence at this time that Фолат may support Выпадение волос при дефиците питательных веществ management. Our evidence grade is F (Evidence Against).

How much Фолат should I take for Выпадение волос при дефиците питательных веществ?

Studies have used various dosages. A commonly studied range is 400 mcg DFE/day. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Фолат?

Reported side effects may include Generally well tolerated, May mask vitamin B12 deficiency symptoms at high doses, Rare: abdominal cramps, insomnia. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Фолат and Выпадение волос при дефиците питательных веществ?

We rate the evidence as Grade F (Evidence Against). This rating is based on 11 peer-reviewed studies with 4,166 total participants. The overall direction of effect is mixed.

Другие ингредиенты для Выпадение волос при дефиците питательных веществ

Селен A Biotin B Vitamin A D L-цистеин D Витамин B12 F

Фолат для других состояний

Телогеновый эффлувиум B

References

[1] Andrea Sechi et al.. Nutrients. 2025. Safety First: A Comprehensive Review of Nutritional Supplements for Hair Loss in Breast Cancer Patients. doi:10.3390/nu17091451 PubMed
[2] Yuxi Li et al.. Arch Toxicol. 2025. 7-Hydroxycannabidiol and 7-carboxycannabidiol induced cytotoxicity via apoptosis and endoplasmic reticulum stress in human hepatic cells. doi:10.1007/s00204-025-04001-7 PubMed
[3] Małgorzata Kalak et al.. Genes (Basel). 2025. Medical Marijuana and Treatment Personalization: The Role of Genetics and Epigenetics in Response to THC and CBD. doi:10.3390/genes16121487 PubMed
[4] F Addo et al.. J Dairy Sci. 2023. Quality and safety of hemp meal as a protein supplement for nonlactating dairy cows. doi:10.3168/jds.2023-23222 PubMed
[5] Hakan Arslan et al.. Dermatol Pract Concept. 2023. Micronutrient Deficiencies and Digital Computerized Phototrichogram Analysis in Telogen Effluvium: a Retrospective Correlation Study in a Tertiary Medical Center. doi:10.5826/dpc.1303a202 PubMed
[6] Ahu Yorulmaz et al.. J Cosmet Dermatol. 2022. Telogen effluvium in daily practice: Patient characteristics, laboratory parameters, and treatment modalities of 3028 patients with telogen effluvium. doi:10.1111/jocd.14413 PubMed
[7] Arno Hazekamp. Med Cannabis Cannabinoids. 2018. The Trouble with CBD Oil. doi:10.1159/000489287 PubMed
[8] Jordan M Thompson et al.. Am J Clin Dermatol. 2017. The Role of Micronutrients in Alopecia Areata: A Review. doi:10.1007/s40257-017-0285-x PubMed
[9] Evelyn J Cheung et al.. J Drugs Dermatol. 2016. Vitamin and Mineral Deficiencies in Patients With Telogen Effluvium: A Retrospective Cross-Sectional Study. PubMed
[10] C Durusoy et al.. Clin Exp Dermatol. 2009. The role of psychological factors and serum zinc, folate and vitamin B12 levels in the aetiology of trichodynia: a case-control … doi:10.1111/j.1365-2230.2008.03165.x PubMed
[11] D H Rushton. Dermatol Clin. 1993. Management of hair loss in women. PubMed

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