Folat için Beslenme Yetersizliğine Bağlı Saç Dökülmesi
F Etki Araştırmalar, bu kullanım için etkili olma ihtimalinin düşük olduğunu göstermektedir.11 çalışmaya, toplam 4,429 katılımcıyla dayanmaktadır. Sonuçlar çalışmalar arasında karışıktır.
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F
Sonuç
The evidence linking folate supplementation to hair regrowth is limited and mixed — folate deficiency may contribute to hair loss in some cases, but supplementation is not well-supported as a general hair loss remedy.
- Results are mixed across 11 studies, with no clear consensus on folate's role in hair loss
- No randomized controlled trials have specifically tested folate supplementation for hair regrowth
- Folate deficiency may be more relevant when caused by medications (e.g., methotrexate) rather than diet
- Blood testing for folate levels may help determine if supplementation is appropriate
Key Study Findings
In Vitro
7-Hydroxycannabidiol and 7-carboxycannabidiol induced cytotoxicity via apoptosis and endoplasmic reticulum stress in human hepatic cells.
Dose: None
vs: Untreated hepatic cells
Outcome: Cytotoxicity via apoptosis and ER stress
Etki: None
None
Popülasyon: Primary human hepatocytes and HepG2 cells
Review
Safety First: A Comprehensive Review of Nutritional Supplements for Hair Loss in Breast Cancer Patients.
Dose: None
vs: Placebo
Etki: None
None
Review
Medical Marijuana and Treatment Personalization: The Role of Genetics and Epigenetics in Response to THC …
Dose: None
vs: None
Outcome: None
Etki: None
None
Popülasyon: Review of pharmacogenomics of THC and CBD
In Vitro
2 weeks
Quality and safety of hemp meal as a protein supplement for nonlactating dairy cows.
Dose: 10.2% d
vs: None
Outcome: glycemic control
Etki: None
None
Popülasyon: Cows
Case-control
n=973
Micronutrient Deficiencies and Digital Computerized Phototrichogram Analysis in Telogen Effluvium: a Retrospective Correlation Study in …
Dose: None
vs: Placebo
Etki: r=0.417 (HGB and AHR in females)
p=0.008
retrospective cohort study
n=3028
Telogen effluvium in daily practice: Patient characteristics, laboratory parameters, and treatment modalities of 3028 patients …
Dose: standard replacement doses
vs: Placebo
Etki: vitamin D deficient: 72.2%; B12 deficient: 30.7%; iron deficiency anemia: 6.2%
None
Key Statistics
11
Çalışmalar
4166
Katılımcılar
↔
Mixed
F
Derece
Referenced Papers
Nutrients
2025
2 atıf
Archives of toxicology
2025
1 atıf
Genes
2025
1 atıf
Journal of dairy …
2023
8 atıf
Dermatology practical & …
2023
4 atıf
Journal of cosmetic …
2022
22 atıf
Medical cannabis and …
2018
158 atıf
American journal of …
2017
104 atıf
Journal of drugs …
2016
56 atıf
Clinical and experimental …
2009
34 atıf
Dermatologic clinics
1993
38 atıf
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
Yaygın Kullanılan Dozajlar
- general:
- 400 mcg DFE/day
Üst sınır: 1,000 mcg/day (synthetic folic acid)
Araştırmalarda İncelenen Dozajlar
| Dozaj | Süre | Etki | N |
|---|---|---|---|
| None | -- | Negative | -- |
| None | -- | Mixed | -- |
| None | -- | Mixed | -- |
| 10.2% d | 2 weeks | Mixed | -- |
| None | -- | Positive | 973 |
| standard replacement doses | -- | Neutral | 3028 |
| None | -- | Positive | -- |
| None | -- | Negative | -- |
En iyi alım zamanı: With meals for better absorption
Safety & Side Effects
Bildirilen Yan Etkiler
- ⚠ Generally well tolerated
- ⚠ May mask vitamin B12 deficiency symptoms at high doses
- ⚠ Rare: abdominal cramps, insomnia
Bilinen Etkileşimler
- ● Methotrexate (folate antagonist; consult physician)
- ● Anticonvulsants (phenytoin, carbamazepine) may reduce folate levels
- ● Sulfasalazine (reduces folate absorption)
Tolere edilebilir üst alım: 1,000 mcg/day (synthetic folic acid)
Herhangi bir takviye kullanmaya başlamadan önce mutlaka sağlık uzmanınıza danışın.Herhangi bir takviye başlatmadan önce her zaman sağlık uzmanınıza danışın.
Frequently Asked Questions
Does Folat help with Beslenme Yetersizliğine Bağlı Saç Dökülmesi?
Based on 11 studies with 4,166 participants, there is insufficient evidence at this time that Folat may support Beslenme Yetersizliğine Bağlı Saç Dökülmesi management. Our evidence grade is F (Evidence Against).
How much Folat should I take for Beslenme Yetersizliğine Bağlı Saç Dökülmesi?
Studies have used various dosages. A commonly studied range is 400 mcg DFE/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Folat?
Reported side effects may include Generally well tolerated, May mask vitamin B12 deficiency symptoms at high doses, Rare: abdominal cramps, insomnia. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Folat and Beslenme Yetersizliğine Bağlı Saç Dökülmesi?
We rate the evidence as Grade F (Evidence Against). This rating is based on 11 peer-reviewed studies with 4,166 total participants. The overall direction of effect is mixed.
Related Evidence
Şu durum için diğer içerikler: Beslenme Yetersizliğine Bağlı Saç Dökülmesi
Folat diğer sağlık durumları için
References
- [1] Andrea Sechi et al.. Nutrients. 2025. Safety First: A Comprehensive Review of Nutritional Supplements for Hair Loss in Breast Cancer Patients. doi:10.3390/nu17091451 PubMed
- [2] Yuxi Li et al.. Arch Toxicol. 2025. 7-Hydroxycannabidiol and 7-carboxycannabidiol induced cytotoxicity via apoptosis and endoplasmic reticulum stress in human hepatic cells. doi:10.1007/s00204-025-04001-7 PubMed
- [3] Małgorzata Kalak et al.. Genes (Basel). 2025. Medical Marijuana and Treatment Personalization: The Role of Genetics and Epigenetics in Response to THC and CBD. doi:10.3390/genes16121487 PubMed
- [4] F Addo et al.. J Dairy Sci. 2023. Quality and safety of hemp meal as a protein supplement for nonlactating dairy cows. doi:10.3168/jds.2023-23222 PubMed
- [5] Hakan Arslan et al.. Dermatol Pract Concept. 2023. Micronutrient Deficiencies and Digital Computerized Phototrichogram Analysis in Telogen Effluvium: a Retrospective Correlation Study in a Tertiary Medical Center. doi:10.5826/dpc.1303a202 PubMed
- [6] Ahu Yorulmaz et al.. J Cosmet Dermatol. 2022. Telogen effluvium in daily practice: Patient characteristics, laboratory parameters, and treatment modalities of 3028 patients with telogen effluvium. doi:10.1111/jocd.14413 PubMed
- [7] Arno Hazekamp. Med Cannabis Cannabinoids. 2018. The Trouble with CBD Oil. doi:10.1159/000489287 PubMed
- [8] Jordan M Thompson et al.. Am J Clin Dermatol. 2017. The Role of Micronutrients in Alopecia Areata: A Review. doi:10.1007/s40257-017-0285-x PubMed
- [9] Evelyn J Cheung et al.. J Drugs Dermatol. 2016. Vitamin and Mineral Deficiencies in Patients With Telogen Effluvium: A Retrospective Cross-Sectional Study. PubMed
- [10] C Durusoy et al.. Clin Exp Dermatol. 2009. The role of psychological factors and serum zinc, folate and vitamin B12 levels in the aetiology of trichodynia: a case-control … doi:10.1111/j.1365-2230.2008.03165.x PubMed
- [11] D H Rushton. Dermatol Clin. 1993. Management of hair loss in women. PubMed
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