B12 Vitamini için Beslenme Yetersizliğine Bağlı Saç Dökülmesi
F Etki Araştırmalar, bu kullanım için etkili olma ihtimalinin düşük olduğunu göstermektedir.20 çalışmaya, toplam 8,355 katılımcıyla dayanmaktadır. Sonuçlar çalışmalar arasında karışıktır.
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F
Sonuç
Research shows mixed results for vitamin B12 and hair loss — while deficiency may contribute to hair thinning, supplementation is unlikely to help unless you have a confirmed B12 deficiency.
- Mixed results across 20 studies — no consistent benefit from supplementation
- Some studies find lower B12 levels in hair loss patients, others do not
- No large-scale RCTs testing B12 supplementation specifically for hair regrowth
- Supplementation may only help if a genuine B12 deficiency is present
Key Study Findings
retrospective observational
n=113
Telogen Effluvium Following Coronavirus Disease-2019 Infection: A Retrospective Study of 113 Cases.
Dose: None
vs: Placebo
Etki: None
None
Retrospective cohort
n=2851
Retrospective Review of 2851 Female Patients With Telogen Effluvium: A Single-Center Experience.
Dose: None
vs: Placebo
Etki: Ferritin low in 46.5% of patients; iron deficiency in 29.5%
p<0.05
Review
Medical Marijuana and Treatment Personalization: The Role of Genetics and Epigenetics in Response to THC …
Dose: None
vs: None
Outcome: None
Etki: None
None
Popülasyon: Review of pharmacogenomics of THC and CBD
case-control study
n=180
A comprehensive investigation of biochemical status in patients with telogen effluvium: Analysis of Hb, ferritin, …
Dose: not applicable
vs: Placebo
Etki: None
None
Cross-Sectional Study
n=108
Evaluation of the relationship of digital phototrichogram findings of patients with diffuse hair loss with …
Dose: None
vs: Placebo
Etki: None
0.05
Case-control
n=973
Micronutrient Deficiencies and Digital Computerized Phototrichogram Analysis in Telogen Effluvium: a Retrospective Correlation Study in …
Dose: None
vs: Placebo
Etki: r=0.417 (HGB and AHR in females)
p=0.008
Key Statistics
19
Çalışmalar
8130
Katılımcılar
↔
Mixed
F
Derece
Referenced Papers
Retrospective Review of 2851 Female Patients With Telogen Effluvium: A Single-Center Experience.
Other
Journal of cosmetic …
2025
4 atıf
Genes
2025
1 atıf
Telogen Effluvium Following Coronavirus Disease-2019 Infection: A Retrospective Study of 113 Cases.
Other
International journal of …
2025
Journal of cosmetic …
2024
7 atıf
Northern clinics of …
2024
1 atıf
JAMA
2023
49 atıf
Dermatology practical & …
2023
4 atıf
Sports medicine - …
2022
34 atıf
Frontiers in pharmacology
2022
31 atıf
Journal of cosmetic …
2022
22 atıf
Turkish journal of …
2022
8 atıf
Journal of pain …
2020
56 atıf
NonScarring Diffuse Hair Loss in Women: a Clinico-Etiological Study from tertiary care center in North-West India.
Observational
Journal of cosmetic …
2019
25 atıf
American journal of …
2017
104 atıf
Journal of drugs …
2016
56 atıf
Dermatology research and …
2016
26 atıf
Acta dermatovenerologica Croatica …
2016
6 atıf
Prostaglandins, leukotrienes, and …
2015
40 atıf
Clinical and experimental …
2009
34 atıf
Dermatologic clinics
1993
38 atıf
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
Yaygın Kullanılan Dozajlar
- general:
- 2.4 mcg/day
- deficiency:
- 1,000-2,000 mcg/day
Üst sınır: No established UL
Araştırmalarda İncelenen Dozajlar
| Dozaj | Süre | Etki | N |
|---|---|---|---|
| None | -- | Neutral | 113 |
| None | -- | Neutral | 2851 |
| None | -- | Mixed | -- |
| not applicable | -- | Mixed | 180 |
| None | -- | Mixed | 108 |
| None | -- | Positive | 973 |
| None | -- | Neutral | -- |
| 300 mg single dose | -- | Mixed | 9 |
En iyi alım zamanı: With meals; sublingual form can be taken any time
Safety & Side Effects
Bildirilen Yan Etkiler
- ⚠ Generally well tolerated even at high doses
- ⚠ Rare allergic reactions (itching, swelling)
- ⚠ Mild diarrhea or nausea at very high doses
Bilinen Etkileşimler
- ● Metformin (reduces B12 absorption by 10-30%)
- ● Proton pump inhibitors and H2 blockers (reduce B12 absorption)
- ● Colchicine (may reduce B12 absorption)
Tolere edilebilir üst alım: No established UL
Herhangi bir takviye kullanmaya başlamadan önce mutlaka sağlık uzmanınıza danışın.Herhangi bir takviye başlatmadan önce her zaman sağlık uzmanınıza danışın.
Frequently Asked Questions
Does B12 Vitamini help with Beslenme Yetersizliğine Bağlı Saç Dökülmesi?
Based on 19 studies with 8,130 participants, there is insufficient evidence at this time that B12 Vitamini may support Beslenme Yetersizliğine Bağlı Saç Dökülmesi management. Our evidence grade is F (Evidence Against).
How much B12 Vitamini should I take for Beslenme Yetersizliğine Bağlı Saç Dökülmesi?
Studies have used various dosages. A commonly studied range is 2.4 mcg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of B12 Vitamini?
Reported side effects may include Generally well tolerated even at high doses, Rare allergic reactions (itching, swelling), Mild diarrhea or nausea at very high doses. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for B12 Vitamini and Beslenme Yetersizliğine Bağlı Saç Dökülmesi?
We rate the evidence as Grade F (Evidence Against). This rating is based on 19 peer-reviewed studies with 8,130 total participants. The overall direction of effect is mixed.
Related Evidence
Şu durum için diğer içerikler: Beslenme Yetersizliğine Bağlı Saç Dökülmesi
B12 Vitamini diğer sağlık durumları için
References
- [1] Ömer Karakoyun et al.. J Cosmet Dermatol. 2025. Retrospective Review of 2851 Female Patients With Telogen Effluvium: A Single-Center Experience. doi:10.1111/jocd.70037 PubMed
- [2] Małgorzata Kalak et al.. Genes (Basel). 2025. Medical Marijuana and Treatment Personalization: The Role of Genetics and Epigenetics in Response to THC and CBD. doi:10.3390/genes16121487 PubMed
- [3] Namrata Chhabra et al.. Int J Trichology. 2025. Telogen Effluvium Following Coronavirus Disease-2019 Infection: A Retrospective Study of 113 Cases. doi:10.4103/ijt.ijt_38_22 PubMed
- [4] Irem Nur Durusu Turkoglu et al.. J Cosmet Dermatol. 2024. A comprehensive investigation of biochemical status in patients with telogen effluvium: Analysis of Hb, ferritin, vitamin B12, vitamin D, thyroid … doi:10.1111/jocd.16512 PubMed
- [5] Leyla Bilik et al.. North Clin Istanb. 2024. Evaluation of the relationship of digital phototrichogram findings of patients with diffuse hair loss with blood TSH, ferritin and vitamin … doi:10.14744/nci.2023.33269 PubMed
- [6] Pieter A Cohen et al.. JAMA. 2023. Quantity of Melatonin and CBD in Melatonin Gummies Sold in the US. doi:10.1001/jama.2023.2296 PubMed
- [7] Hakan Arslan et al.. Dermatol Pract Concept. 2023. Micronutrient Deficiencies and Digital Computerized Phototrichogram Analysis in Telogen Effluvium: a Retrospective Correlation Study in a Tertiary Medical Center. doi:10.5826/dpc.1303a202 PubMed
- [8] Ayshe Sahinovic et al.. Sports Med Open. 2022. Effects of Cannabidiol on Exercise Physiology and Bioenergetics: A Randomised Controlled Pilot Trial. doi:10.1186/s40798-022-00417-y PubMed
- [9] Arash Salehi et al.. Front Pharmacol. 2022. Differentiating Cannabis Products: Drugs, Food, and Supplements. doi:10.3389/fphar.2022.906038 PubMed
- [10] Ahu Yorulmaz et al.. J Cosmet Dermatol. 2022. Telogen effluvium in daily practice: Patient characteristics, laboratory parameters, and treatment modalities of 3028 patients with telogen effluvium. doi:10.1111/jocd.14413 PubMed
- [11] Ümran Öner et al.. Turk J Med Sci. 2022. Nonscarring scalp alopecia: Which laboratory analysis should we perform on whom? doi:10.3906/sag-2106-28 PubMed
- [12] Uma Anand et al.. J Pain Res. 2020. CBD Effects on TRPV1 Signaling Pathways in Cultured DRG Neurons. doi:10.2147/JPR.S258433 PubMed
- [13] Kavita Poonia et al.. J Cosmet Dermatol. 2019. NonScarring Diffuse Hair Loss in Women: a Clinico-Etiological Study from tertiary care center in North-West India. doi:10.1111/jocd.12559 PubMed
- [14] Jordan M Thompson et al.. Am J Clin Dermatol. 2017. The Role of Micronutrients in Alopecia Areata: A Review. doi:10.1007/s40257-017-0285-x PubMed
- [15] Evelyn J Cheung et al.. J Drugs Dermatol. 2016. Vitamin and Mineral Deficiencies in Patients With Telogen Effluvium: A Retrospective Cross-Sectional Study. PubMed
- [16] Kirti Deo et al.. Dermatol Res Pract. 2016. Clinicoepidemiological Observational Study of Acquired Alopecias in Females Correlating with Anemia and Thyroid Function. doi:10.1155/2016/6279108 PubMed
- [17] Jana Zímová et al.. Acta Dermatovenerol Croat. 2016. Trichotillomania: Bizzare Patern of Hair Loss at 11-Year-old Girl. PubMed
- [18] Amrita Khaire et al.. Prostaglandins Leukot Essent Fatty Acids. 2015. Vitamin B12 and omega-3 fatty acids together regulate lipid metabolism in Wistar rats. doi:10.1016/j.plefa.2015.04.006 PubMed
- [19] C Durusoy et al.. Clin Exp Dermatol. 2009. The role of psychological factors and serum zinc, folate and vitamin B12 levels in the aetiology of trichodynia: a case-control … doi:10.1111/j.1365-2230.2008.03165.x PubMed
- [20] D H Rushton. Dermatol Clin. 1993. Management of hair loss in women. PubMed
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