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비타민B12 관련 영양 결핍성 탈모

F 효과 연구에 따르면 이 용도에 효과가 있을 가능성은 낮은 것으로 나타납니다.

총 8,355명의 참여자를 대상으로 한 20건의 연구에 근거합니다. 연구 결과는 혼재되어 있습니다.

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F

결론

Research shows mixed results for vitamin B12 and hair loss — while deficiency may contribute to hair thinning, supplementation is unlikely to help unless you have a confirmed B12 deficiency.

  • Mixed results across 20 studies — no consistent benefit from supplementation
  • Some studies find lower B12 levels in hair loss patients, others do not
  • No large-scale RCTs testing B12 supplementation specifically for hair regrowth
  • Supplementation may only help if a genuine B12 deficiency is present

Key Study Findings

retrospective observational n=113
Telogen Effluvium Following Coronavirus Disease-2019 Infection: A Retrospective Study of 113 Cases.
Dose: None vs: Placebo 효과: None None
Retrospective cohort n=2851
Retrospective Review of 2851 Female Patients With Telogen Effluvium: A Single-Center Experience.
Dose: None vs: Placebo 효과: Ferritin low in 46.5% of patients; iron deficiency in 29.5% p<0.05
Review
Medical Marijuana and Treatment Personalization: The Role of Genetics and Epigenetics in Response to THC …
Dose: None vs: None Outcome: None 효과: None None

대상 집단: Review of pharmacogenomics of THC and CBD

Key Statistics

19

연구

8130

참여자

Mixed

F

등급

Referenced Papers

Frontiers in pharmacology 2022 31 인용
American journal of … 2017 104 인용
Acta dermatovenerologica Croatica … 2016 6 인용
Prostaglandins, leukotrienes, and … 2015 40 인용
Dermatologic clinics 1993 38 인용

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

일반적으로 사용되는 용량

general:
2.4 mcg/day
deficiency:
1,000-2,000 mcg/day

상한량: No established UL

연구에서 사용된 용량

용량 기간 효과 N
None -- Neutral 113
None -- Neutral 2851
None -- Mixed --
not applicable -- Mixed 180
None -- Mixed 108
None -- Positive 973
None -- Neutral --
300 mg single dose -- Mixed 9

권장 복용 시간: With meals; sublingual form can be taken any time

Safety & Side Effects

보고된 부작용

  • Generally well tolerated even at high doses
  • Rare allergic reactions (itching, swelling)
  • Mild diarrhea or nausea at very high doses

알려진 상호작용

  • Metformin (reduces B12 absorption by 10-30%)
  • Proton pump inhibitors and H2 blockers (reduce B12 absorption)
  • Colchicine (may reduce B12 absorption)

일일 최대 섭취 허용량: No established UL

건강기능식품을 복용하기 전에 반드시 의료 전문가와 상담하십시오.

Frequently Asked Questions

Does 비타민B12 help with 영양 결핍성 탈모?
Based on 19 studies with 8,130 participants, there is insufficient evidence at this time that 비타민B12 may support 영양 결핍성 탈모 management. Our evidence grade is F (Evidence Against).
How much 비타민B12 should I take for 영양 결핍성 탈모?
Studies have used various dosages. A commonly studied range is 2.4 mcg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of 비타민B12?
Reported side effects may include Generally well tolerated even at high doses, Rare allergic reactions (itching, swelling), Mild diarrhea or nausea at very high doses. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for 비타민B12 and 영양 결핍성 탈모?
We rate the evidence as Grade F (Evidence Against). This rating is based on 19 peer-reviewed studies with 8,130 total participants. The overall direction of effect is mixed.

비타민B12 다른 건강 상태에 대한 근거

References

  1. [1] Ömer Karakoyun et al.. J Cosmet Dermatol. 2025. Retrospective Review of 2851 Female Patients With Telogen Effluvium: A Single-Center Experience. doi:10.1111/jocd.70037 PubMed
  2. [2] Małgorzata Kalak et al.. Genes (Basel). 2025. Medical Marijuana and Treatment Personalization: The Role of Genetics and Epigenetics in Response to THC and CBD. doi:10.3390/genes16121487 PubMed
  3. [3] Namrata Chhabra et al.. Int J Trichology. 2025. Telogen Effluvium Following Coronavirus Disease-2019 Infection: A Retrospective Study of 113 Cases. doi:10.4103/ijt.ijt_38_22 PubMed
  4. [4] Irem Nur Durusu Turkoglu et al.. J Cosmet Dermatol. 2024. A comprehensive investigation of biochemical status in patients with telogen effluvium: Analysis of Hb, ferritin, vitamin B12, vitamin D, thyroid … doi:10.1111/jocd.16512 PubMed
  5. [5] Leyla Bilik et al.. North Clin Istanb. 2024. Evaluation of the relationship of digital phototrichogram findings of patients with diffuse hair loss with blood TSH, ferritin and vitamin … doi:10.14744/nci.2023.33269 PubMed
  6. [6] Pieter A Cohen et al.. JAMA. 2023. Quantity of Melatonin and CBD in Melatonin Gummies Sold in the US. doi:10.1001/jama.2023.2296 PubMed
  7. [7] Hakan Arslan et al.. Dermatol Pract Concept. 2023. Micronutrient Deficiencies and Digital Computerized Phototrichogram Analysis in Telogen Effluvium: a Retrospective Correlation Study in a Tertiary Medical Center. doi:10.5826/dpc.1303a202 PubMed
  8. [8] Ayshe Sahinovic et al.. Sports Med Open. 2022. Effects of Cannabidiol on Exercise Physiology and Bioenergetics: A Randomised Controlled Pilot Trial. doi:10.1186/s40798-022-00417-y PubMed
  9. [9] Arash Salehi et al.. Front Pharmacol. 2022. Differentiating Cannabis Products: Drugs, Food, and Supplements. doi:10.3389/fphar.2022.906038 PubMed
  10. [10] Ahu Yorulmaz et al.. J Cosmet Dermatol. 2022. Telogen effluvium in daily practice: Patient characteristics, laboratory parameters, and treatment modalities of 3028 patients with telogen effluvium. doi:10.1111/jocd.14413 PubMed
  11. [11] Ümran Öner et al.. Turk J Med Sci. 2022. Nonscarring scalp alopecia: Which laboratory analysis should we perform on whom? doi:10.3906/sag-2106-28 PubMed
  12. [12] Uma Anand et al.. J Pain Res. 2020. CBD Effects on TRPV1 Signaling Pathways in Cultured DRG Neurons. doi:10.2147/JPR.S258433 PubMed
  13. [13] Kavita Poonia et al.. J Cosmet Dermatol. 2019. NonScarring Diffuse Hair Loss in Women: a Clinico-Etiological Study from tertiary care center in North-West India. doi:10.1111/jocd.12559 PubMed
  14. [14] Jordan M Thompson et al.. Am J Clin Dermatol. 2017. The Role of Micronutrients in Alopecia Areata: A Review. doi:10.1007/s40257-017-0285-x PubMed
  15. [15] Evelyn J Cheung et al.. J Drugs Dermatol. 2016. Vitamin and Mineral Deficiencies in Patients With Telogen Effluvium: A Retrospective Cross-Sectional Study. PubMed
  16. [16] Kirti Deo et al.. Dermatol Res Pract. 2016. Clinicoepidemiological Observational Study of Acquired Alopecias in Females Correlating with Anemia and Thyroid Function. doi:10.1155/2016/6279108 PubMed
  17. [17] Jana Zímová et al.. Acta Dermatovenerol Croat. 2016. Trichotillomania: Bizzare Patern of Hair Loss at 11-Year-old Girl. PubMed
  18. [18] Amrita Khaire et al.. Prostaglandins Leukot Essent Fatty Acids. 2015. Vitamin B12 and omega-3 fatty acids together regulate lipid metabolism in Wistar rats. doi:10.1016/j.plefa.2015.04.006 PubMed
  19. [19] C Durusoy et al.. Clin Exp Dermatol. 2009. The role of psychological factors and serum zinc, folate and vitamin B12 levels in the aetiology of trichodynia: a case-control … doi:10.1111/j.1365-2230.2008.03165.x PubMed
  20. [20] D H Rushton. Dermatol Clin. 1993. Management of hair loss in women. PubMed

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