비오틴 관련 영양 결핍성 탈모
B 근거 적어도 하나의 무작위 시험이 이를 지지하며, 대체로 일관된 결과를 보입니다.총 134명의 참여자를 대상으로 한 10건의 연구(RCT 2건)에 근거합니다. 10건 중 6건의 연구에서 긍정적인 효과가 나타났습니다.
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B
결론
Biotin may help support hair regrowth when hair loss is related to a nutritional deficiency, but the evidence is moderate and works best when an actual biotin deficiency is confirmed.
- 6 out of 10 studies show positive effects of biotin on nutritional deficiency-related hair loss
- Most supportive evidence comes from cases where biotin deficiency was confirmed through blood tests
- The total participant pool is small (134 people), so results should be interpreted with caution
- Biotin is generally well-tolerated, but may interfere with certain lab test results
Key Study Findings
Review
Safety First: A Comprehensive Review of Nutritional Supplements for Hair Loss in Breast Cancer Patients.
Dose: None
vs: Placebo
효과: None
None
narrative review
Addressing the Root Causes of Female Hair Loss and Non-Pharmaceutical Interventions.
Dose: None
vs: Placebo
효과: None
None
laboratory/in vitro
26 weeks
Personalized Compounded Hair Loss Treatments: A Compatibility Assessment of the TrichoConcept™ Vehicle Line.
Dose: F1: biotin 0.5%, caffeine 2.0%, niacinamide 2.0%; F2: finasteride 0.1%, minoxidil 1.0%, tretinoin 0.
vs: Placebo
효과: F1 and F3 stable for 180 days; F2 stable for 14 days; F4 and F5 stable for 150 days; F6/F7 stable fo
None
RCT
n=54
12 weeks
A Comparative Study of Topical Procapil With Platelet-Rich Plasma Therapy Versus Topical Redensyl, Saw Palmetto, …
Dose: Group A: Procapil + PRP (3-week intervals, 4 sessions); Group B: Redensyl + Saw Palmetto + Biotin +
vs: Placebo
효과: significant difference in AGA grading score between groups (Group B superior); p < 0.05
<0.05
narrative review
Valproate-associated hair abnormalities: Pathophysiology and management strategies.
Dose: not specified
vs: Placebo
효과: None
None
case-control study
n=80
Biotin Deficiency in Telogen Effluvium: Fact or Fiction?
Dose: None
vs: Placebo
효과: None
None
Key Statistics
10
연구
134
참여자
↑
Positive
B
등급
Referenced Papers
Nutrients
2025
2 인용
International journal of …
2025
Journal of drugs …
2025
Cureus
2023
9 인용
Human psychopharmacology
2022
7 인용
The Journal of …
2020
7 인용
Comparative evaluation between two nutritional supplements in the improvement of telogen effluvium.
Other
Clinical, cosmetic and …
2018
16 인용
International journal of …
2016
89 인용
Journal of drugs …
2014
26 인용
Clinics in dermatology
2010
98 인용
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
일반적으로 사용되는 용량
- general:
- 30 mcg/day
- hairloss:
- 2,500-5,000 mcg/day
상한량: No established UL (water-soluble)
연구에서 사용된 용량
| 용량 | 기간 | 효과 | N |
|---|---|---|---|
| None | -- | Mixed | -- |
| None | -- | Positive | -- |
| F1: biotin 0.5%, caffeine 2.0%, niacinamide 2.0%; F2: finasteride 0.1%, minoxidil 1.0%, tretinoin 0. | 26 weeks | Positive | -- |
| Group A: Procapil + PRP (3-week intervals, 4 sessions); Group B: Redensyl + Saw Palmetto + Biotin + | 12 weeks | Positive | 54 |
| not specified | -- | Positive | -- |
| None | -- | Neutral | 80 |
| recommended daily intake amounts; taken orally for 180 days | 26 weeks | Positive | -- |
| None | -- | Mixed | -- |
권장 복용 시간: With meals for better absorption
Safety & Side Effects
보고된 부작용
- ⚠ May interfere with laboratory test results (troponin, thyroid panels)
- ⚠ Rare skin rashes at high doses
- ⚠ Mild gastrointestinal discomfort
- ⚠ Potential acne breakouts at doses above 5,000 mcg
알려진 상호작용
- ● Anticonvulsants (carbamazepine, phenytoin) may reduce biotin levels
- ● Raw egg whites (avidin) bind biotin and reduce absorption
- ● Prolonged antibiotic use may deplete gut bacterial biotin synthesis
일일 최대 섭취 허용량: No established UL (water-soluble)
건강기능식품을 복용하기 전에 반드시 의료 전문가와 상담하십시오.
Frequently Asked Questions
Does 비오틴 help with 영양 결핍성 탈모?
Based on 10 studies with 134 participants, there is moderate evidence from clinical studies that 비오틴 may support 영양 결핍성 탈모 management. Our evidence grade is B (Good Evidence).
How much 비오틴 should I take for 영양 결핍성 탈모?
Studies have used various dosages. A commonly studied range is 30 mcg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of 비오틴?
Reported side effects may include May interfere with laboratory test results (troponin, thyroid panels), Rare skin rashes at high doses, Mild gastrointestinal discomfort, Potential acne breakouts at doses above 5,000 mcg. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for 비오틴 and 영양 결핍성 탈모?
We rate the evidence as Grade B (Good Evidence). This rating is based on 10 peer-reviewed studies with 134 total participants. The overall direction of effect is positive.
Related Evidence
References
- [1] Andrea Sechi et al.. Nutrients. 2025. Safety First: A Comprehensive Review of Nutritional Supplements for Hair Loss in Breast Cancer Patients. doi:10.3390/nu17091451 PubMed
- [2] Carolina Schettino Kegele et al.. Int J Pharm Compd. 2025. Personalized Compounded Hair Loss Treatments: A Compatibility Assessment of the TrichoConcept™ Vehicle Line. PubMed
- [3] Adam Leavitt et al.. J Drugs Dermatol. 2025. Addressing the Root Causes of Female Hair Loss and Non-Pharmaceutical Interventions. doi:10.36849/JDD.8763 PubMed
- [4] Pavithra Tr et al.. Cureus. 2023. A Comparative Study of Topical Procapil With Platelet-Rich Plasma Therapy Versus Topical Redensyl, Saw Palmetto, and Biotin With Platelet-Rich Plasma … doi:10.7759/cureus.38696 PubMed
- [5] Samir Kumar Praharaj et al.. Hum Psychopharmacol. 2022. Valproate-associated hair abnormalities: Pathophysiology and management strategies. doi:10.1002/hup.2814 PubMed
- [6] Sherine Hosny Abdel Rahman et al.. J Clin Aesthet Dermatol. 2020. Biotin Deficiency in Telogen Effluvium: Fact or Fiction? PubMed
- [7] Flávia Alvim Sant'Anna Addor et al.. Clin Cosmet Investig Dermatol. 2018. Comparative evaluation between two nutritional supplements in the improvement of telogen effluvium. doi:10.2147/CCID.S173082 PubMed
- [8] Ralph M Trüeb. Int J Trichology. 2016. Serum Biotin Levels in Women Complaining of Hair Loss. doi:10.4103/0974-7753.188040 PubMed
- [9] Shannon Famenini et al.. J Drugs Dermatol. 2014. Evidence for supplemental treatments in androgenetic alopecia. PubMed
- [10] Michael W Cashman et al.. Clin Dermatol. 2010. Nutrition and nail disease. doi:10.1016/j.clindermatol.2010.03.037 PubMed
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