Biotin لـ تساقط الشعر بسبب نقص التغذية
B الأدلة تدعم ذلك تجربة عشوائية واحدة على الأقل، مع نتائج متسقة في معظمها.بناءً على 10 دراسة (2 RCTs) بمشاركة 134 مشاركًا إجمالاً. 6/10 دراسة تُظهر تأثيرات إيجابية.
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B
الخلاصة
Biotin may help support hair regrowth when hair loss is related to a nutritional deficiency, but the evidence is moderate and works best when an actual biotin deficiency is confirmed.
- 6 out of 10 studies show positive effects of biotin on nutritional deficiency-related hair loss
- Most supportive evidence comes from cases where biotin deficiency was confirmed through blood tests
- The total participant pool is small (134 people), so results should be interpreted with caution
- Biotin is generally well-tolerated, but may interfere with certain lab test results
Key Study Findings
Review
Safety First: A Comprehensive Review of Nutritional Supplements for Hair Loss in Breast Cancer Patients.
Dose: None
مقابل: Placebo
التأثير: None
None
narrative review
Addressing the Root Causes of Female Hair Loss and Non-Pharmaceutical Interventions.
Dose: None
مقابل: Placebo
التأثير: None
None
laboratory/in vitro
26 weeks
Personalized Compounded Hair Loss Treatments: A Compatibility Assessment of the TrichoConcept™ Vehicle Line.
Dose: F1: biotin 0.5%, caffeine 2.0%, niacinamide 2.0%; F2: finasteride 0.1%, minoxidil 1.0%, tretinoin 0.
مقابل: Placebo
التأثير: F1 and F3 stable for 180 days; F2 stable for 14 days; F4 and F5 stable for 150 days; F6/F7 stable fo
None
RCT
n=54
12 weeks
A Comparative Study of Topical Procapil With Platelet-Rich Plasma Therapy Versus Topical Redensyl, Saw Palmetto, …
Dose: Group A: Procapil + PRP (3-week intervals, 4 sessions); Group B: Redensyl + Saw Palmetto + Biotin +
مقابل: Placebo
التأثير: significant difference in AGA grading score between groups (Group B superior); p < 0.05
<0.05
narrative review
Valproate-associated hair abnormalities: Pathophysiology and management strategies.
Dose: not specified
مقابل: Placebo
التأثير: None
None
case-control study
n=80
Biotin Deficiency in Telogen Effluvium: Fact or Fiction?
Dose: None
مقابل: Placebo
التأثير: None
None
Key Statistics
10
الدراسات
134
المشاركون
↑
Positive
B
التقييم
Referenced Papers
Nutrients
2025
2 اقتباسات
International journal of …
2025
Journal of drugs …
2025
Cureus
2023
9 اقتباسات
Human psychopharmacology
2022
7 اقتباسات
The Journal of …
2020
7 اقتباسات
Comparative evaluation between two nutritional supplements in the improvement of telogen effluvium.
Other
Clinical, cosmetic and …
2018
16 اقتباسات
International journal of …
2016
89 اقتباسات
Journal of drugs …
2014
26 اقتباسات
Clinics in dermatology
2010
98 اقتباسات
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
الجرعات الشائعة
- general:
- 30 mcg/day
- hairloss:
- 2,500-5,000 mcg/day
الحد الأعلى: No established UL (water-soluble)
الجرعات المدروسة في الأبحاث
| الجرعة | المدة | التأثير | ن |
|---|---|---|---|
| None | -- | Mixed | -- |
| None | -- | Positive | -- |
| F1: biotin 0.5%, caffeine 2.0%, niacinamide 2.0%; F2: finasteride 0.1%, minoxidil 1.0%, tretinoin 0. | 26 weeks | Positive | -- |
| Group A: Procapil + PRP (3-week intervals, 4 sessions); Group B: Redensyl + Saw Palmetto + Biotin + | 12 weeks | Positive | 54 |
| not specified | -- | Positive | -- |
| None | -- | Neutral | 80 |
| recommended daily intake amounts; taken orally for 180 days | 26 weeks | Positive | -- |
| None | -- | Mixed | -- |
أفضل وقت للتناول: With meals for better absorption
Safety & Side Effects
الآثار الجانبية المُبلّغ عنها
- ⚠ May interfere with laboratory test results (troponin, thyroid panels)
- ⚠ Rare skin rashes at high doses
- ⚠ Mild gastrointestinal discomfort
- ⚠ Potential acne breakouts at doses above 5,000 mcg
التفاعلات المعروفة
- ● Anticonvulsants (carbamazepine, phenytoin) may reduce biotin levels
- ● Raw egg whites (avidin) bind biotin and reduce absorption
- ● Prolonged antibiotic use may deplete gut bacterial biotin synthesis
الحد الأقصى المسموح به: No established UL (water-soluble)
استشر مقدم الرعاية الصحية دائماً قبل البدء بأي مكمل غذائي.
Frequently Asked Questions
Does Biotin help with تساقط الشعر بسبب نقص التغذية?
Based on 10 studies with 134 participants, there is moderate evidence from clinical studies that Biotin may support تساقط الشعر بسبب نقص التغذية management. Our evidence grade is B (Good Evidence).
How much Biotin should I take for تساقط الشعر بسبب نقص التغذية?
Studies have used various dosages. A commonly studied range is 30 mcg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Biotin?
Reported side effects may include May interfere with laboratory test results (troponin, thyroid panels), Rare skin rashes at high doses, Mild gastrointestinal discomfort, Potential acne breakouts at doses above 5,000 mcg. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Biotin and تساقط الشعر بسبب نقص التغذية?
We rate the evidence as Grade B (Good Evidence). This rating is based on 10 peer-reviewed studies with 134 total participants. The overall direction of effect is positive.
Related Evidence
مكونات أخرى لـ تساقط الشعر بسبب نقص التغذية
Biotin لحالات أخرى
References
- [1] Andrea Sechi et al.. Nutrients. 2025. Safety First: A Comprehensive Review of Nutritional Supplements for Hair Loss in Breast Cancer Patients. doi:10.3390/nu17091451 PubMed
- [2] Carolina Schettino Kegele et al.. Int J Pharm Compd. 2025. Personalized Compounded Hair Loss Treatments: A Compatibility Assessment of the TrichoConcept™ Vehicle Line. PubMed
- [3] Adam Leavitt et al.. J Drugs Dermatol. 2025. Addressing the Root Causes of Female Hair Loss and Non-Pharmaceutical Interventions. doi:10.36849/JDD.8763 PubMed
- [4] Pavithra Tr et al.. Cureus. 2023. A Comparative Study of Topical Procapil With Platelet-Rich Plasma Therapy Versus Topical Redensyl, Saw Palmetto, and Biotin With Platelet-Rich Plasma … doi:10.7759/cureus.38696 PubMed
- [5] Samir Kumar Praharaj et al.. Hum Psychopharmacol. 2022. Valproate-associated hair abnormalities: Pathophysiology and management strategies. doi:10.1002/hup.2814 PubMed
- [6] Sherine Hosny Abdel Rahman et al.. J Clin Aesthet Dermatol. 2020. Biotin Deficiency in Telogen Effluvium: Fact or Fiction? PubMed
- [7] Flávia Alvim Sant'Anna Addor et al.. Clin Cosmet Investig Dermatol. 2018. Comparative evaluation between two nutritional supplements in the improvement of telogen effluvium. doi:10.2147/CCID.S173082 PubMed
- [8] Ralph M Trüeb. Int J Trichology. 2016. Serum Biotin Levels in Women Complaining of Hair Loss. doi:10.4103/0974-7753.188040 PubMed
- [9] Shannon Famenini et al.. J Drugs Dermatol. 2014. Evidence for supplemental treatments in androgenetic alopecia. PubMed
- [10] Michael W Cashman et al.. Clin Dermatol. 2010. Nutrition and nail disease. doi:10.1016/j.clindermatol.2010.03.037 PubMed
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