Фолат для Телогеновый эффлувиум
B Доказательства По меньшей мере одно рандомизированное исследование подтверждает это, с в целом согласованными результатами.На основе 6 исследований с участием 4,166 участников. Результаты исследований неоднозначны.
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B
Итог
There is limited evidence connecting folate to telogen effluvium — while low folate levels have been observed in some patients, research does not yet support folate supplementation as a reliable approach for this condition.
- Mixed results across 6 studies — no consistent pattern linking folate levels to telogen effluvium
- All studies are observational; no randomized controlled trials exist for this specific use
- Folate is one of many micronutrients that may play a supporting role in hair health
- A comprehensive nutritional assessment may be more useful than supplementing folate alone
Key Study Findings
Retrospective cohort
n=2851
Retrospective Review of 2851 Female Patients With Telogen Effluvium: A Single-Center Experience.
Dose: None
или: Placebo
Эффект: Ferritin low in 46.5% of patients; iron deficiency in 29.5%
p<0.05
Review
Safety First: A Comprehensive Review of Nutritional Supplements for Hair Loss in Breast Cancer Patients.
Dose: None
или: Placebo
Эффект: None
None
Cross-Sectional Study
n=108
Evaluation of the relationship of digital phototrichogram findings of patients with diffuse hair loss with …
Dose: None
или: Placebo
Эффект: None
0.05
Case-control
n=973
Micronutrient Deficiencies and Digital Computerized Phototrichogram Analysis in Telogen Effluvium: a Retrospective Correlation Study in …
Dose: None
или: Placebo
Эффект: r=0.417 (HGB and AHR in females)
p=0.008
retrospective cohort study
n=3028
Telogen effluvium in daily practice: Patient characteristics, laboratory parameters, and treatment modalities of 3028 patients …
Dose: standard replacement doses
или: Placebo
Эффект: vitamin D deficient: 72.2%; B12 deficient: 30.7%; iron deficiency anemia: 6.2%
None
randomized controlled trial
26 weeks
Comparative evaluation between two nutritional supplements in the improvement of telogen effluvium.
Dose: recommended daily intake amounts; taken orally for 180 days
или: Placebo
Эффект: Group 1 trichoscopy improvement 11.09% vs Group 2 7.76% after 180 days (significant for Group 1 only
P<0.05 for clinical parameters
Key Statistics
10
Исследования
7126
Участники
↔
Mixed
B
Оценка
Referenced Papers
Retrospective Review of 2851 Female Patients With Telogen Effluvium: A Single-Center Experience.
Other
Journal of cosmetic …
2025
4 цитирований
Nutrients
2025
2 цитирований
Northern clinics of …
2024
1 цитирований
Dermatology practical & …
2023
4 цитирований
Journal of cosmetic …
2022
22 цитирований
Journal of photochemistry …
2018
16 цитирований
Comparative evaluation between two nutritional supplements in the improvement of telogen effluvium.
Other
Clinical, cosmetic and …
2018
16 цитирований
Journal of drugs …
2016
56 цитирований
Acta dermatovenerologica Croatica …
2016
6 цитирований
Clinical and experimental …
2009
34 цитирований
Dermatologic clinics
1993
38 цитирований
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
Часто используемые дозировки
- general:
- 400 mcg DFE/day
Верхний предел: 1,000 mcg/day (synthetic folic acid)
Дозировки, изученные в исследованиях
| Дозировка | Длительность | Эффект | N |
|---|---|---|---|
| None | -- | Neutral | 2851 |
| None | -- | Mixed | -- |
| None | -- | Mixed | 108 |
| None | -- | Positive | 973 |
| standard replacement doses | -- | Neutral | 3028 |
| recommended daily intake amounts; taken orally for 180 days | 26 weeks | Positive | -- |
| psychiatric and dermatological management | -- | Neutral | 1 |
| None | -- | Negative | -- |
Лучшее время приёма: With meals for better absorption
Safety & Side Effects
Зарегистрированные побочные эффекты
- ⚠ Generally well tolerated
- ⚠ May mask vitamin B12 deficiency symptoms at high doses
- ⚠ Rare: abdominal cramps, insomnia
Известные взаимодействия
- ● Methotrexate (folate antagonist; consult physician)
- ● Anticonvulsants (phenytoin, carbamazepine) may reduce folate levels
- ● Sulfasalazine (reduces folate absorption)
Допустимый верхний уровень потребления: 1,000 mcg/day (synthetic folic acid)
Всегда консультируйтесь с врачом перед началом приёма любых добавок.Всегда консультируйтесь с лечащим врачом перед началом приёма любой добавки.
Frequently Asked Questions
Does Фолат help with Телогеновый эффлувиум?
Based on 10 studies with 7,126 participants, there is moderate evidence from clinical studies that Фолат may support Телогеновый эффлувиум management. Our evidence grade is B (Good Evidence).
How much Фолат should I take for Телогеновый эффлувиум?
Studies have used various dosages. A commonly studied range is 400 mcg DFE/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Фолат?
Reported side effects may include Generally well tolerated, May mask vitamin B12 deficiency symptoms at high doses, Rare: abdominal cramps, insomnia. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Фолат and Телогеновый эффлувиум?
We rate the evidence as Grade B (Good Evidence). This rating is based on 10 peer-reviewed studies with 7,126 total participants. The overall direction of effect is mixed.
Related Evidence
Другие ингредиенты для Телогеновый эффлувиум
Фолат для других состояний
References
- [1] Ömer Karakoyun et al.. J Cosmet Dermatol. 2025. Retrospective Review of 2851 Female Patients With Telogen Effluvium: A Single-Center Experience. doi:10.1111/jocd.70037 PubMed
- [2] Andrea Sechi et al.. Nutrients. 2025. Safety First: A Comprehensive Review of Nutritional Supplements for Hair Loss in Breast Cancer Patients. doi:10.3390/nu17091451 PubMed
- [3] Leyla Bilik et al.. North Clin Istanb. 2024. Evaluation of the relationship of digital phototrichogram findings of patients with diffuse hair loss with blood TSH, ferritin and vitamin … doi:10.14744/nci.2023.33269 PubMed
- [4] Hakan Arslan et al.. Dermatol Pract Concept. 2023. Micronutrient Deficiencies and Digital Computerized Phototrichogram Analysis in Telogen Effluvium: a Retrospective Correlation Study in a Tertiary Medical Center. doi:10.5826/dpc.1303a202 PubMed
- [5] Ahu Yorulmaz et al.. J Cosmet Dermatol. 2022. Telogen effluvium in daily practice: Patient characteristics, laboratory parameters, and treatment modalities of 3028 patients with telogen effluvium. doi:10.1111/jocd.14413 PubMed
- [6] Thomas Hengl et al.. J Photochem Photobiol B. 2018. Cystine-thiamin-containing hair-growth formulation modulates the response to UV radiation in an in vitro model for growth-limiting conditions of human keratinocytes. doi:10.1016/j.jphotobiol.2018.09.005 PubMed
- [7] Flávia Alvim Sant'Anna Addor et al.. Clin Cosmet Investig Dermatol. 2018. Comparative evaluation between two nutritional supplements in the improvement of telogen effluvium. doi:10.2147/CCID.S173082 PubMed
- [8] Evelyn J Cheung et al.. J Drugs Dermatol. 2016. Vitamin and Mineral Deficiencies in Patients With Telogen Effluvium: A Retrospective Cross-Sectional Study. PubMed
- [9] Jana Zímová et al.. Acta Dermatovenerol Croat. 2016. Trichotillomania: Bizzare Patern of Hair Loss at 11-Year-old Girl. PubMed
- [10] C Durusoy et al.. Clin Exp Dermatol. 2009. The role of psychological factors and serum zinc, folate and vitamin B12 levels in the aetiology of trichodynia: a case-control … doi:10.1111/j.1365-2230.2008.03165.x PubMed
- [11] D H Rushton. Dermatol Clin. 1993. Management of hair loss in women. PubMed
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