Folate cho Telogen Effluvium

Q: Does Folate help with Telogen Effluvium?

Based on 10 studies with 7,126 participants, there is moderate evidence from clinical studies that Folate may support Telogen Effluvium management. Our evidence grade is B (Good Evidence).

Q: How much Folate should I take for Telogen Effluvium?

Studies have used various dosages. A commonly studied range is 400 mcg DFE/day. Always consult your healthcare provider before starting any supplement regimen.

Q: Are there side effects of Folate?

Reported side effects may include Generally well tolerated, May mask vitamin B12 deficiency symptoms at high doses, Rare: abdominal cramps, insomnia. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

Q: How strong is the evidence for Folate and Telogen Effluvium?

We rate the evidence as Grade B (Good Evidence). This rating is based on 10 peer-reviewed studies with 7,126 total participants. The overall direction of effect is mixed.

B Bằng chứng Ít nhất một thử nghiệm ngẫu nhiên ủng hộ điều này, với các kết quả phần lớn nhất quán.

Dựa trên 6 nghiên cứu với 4,166 người tham gia. Kết quả nghiên cứu không đồng nhất.

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Kết luận

There is limited evidence connecting folate to telogen effluvium — while low folate levels have been observed in some patients, research does not yet support folate supplementation as a reliable approach for this condition.

Mixed results across 6 studies — no consistent pattern linking folate levels to telogen effluvium
All studies are observational; no randomized controlled trials exist for this specific use
Folate is one of many micronutrients that may play a supporting role in hair health
A comprehensive nutritional assessment may be more useful than supplementing folate alone

Key Study Findings

Retrospective cohort n=2851

Retrospective Review of 2851 Female Patients With Telogen Effluvium: A Single-Center Experience.

Dose: None so với: Placebo Hiệu quả: Ferritin low in 46.5% of patients; iron deficiency in 29.5% p<0.05

Review

Safety First: A Comprehensive Review of Nutritional Supplements for Hair Loss in Breast Cancer Patients.

Dose: None so với: Placebo Hiệu quả: None None

Cross-Sectional Study n=108

Evaluation of the relationship of digital phototrichogram findings of patients with diffuse hair loss with …

Dose: None so với: Placebo Hiệu quả: None 0.05

Case-control n=973

Micronutrient Deficiencies and Digital Computerized Phototrichogram Analysis in Telogen Effluvium: a Retrospective Correlation Study in …

Dose: None so với: Placebo Hiệu quả: r=0.417 (HGB and AHR in females) p=0.008

retrospective cohort study n=3028

Telogen effluvium in daily practice: Patient characteristics, laboratory parameters, and treatment modalities of 3028 patients …

Dose: standard replacement doses so với: Placebo Hiệu quả: vitamin D deficient: 72.2%; B12 deficient: 30.7%; iron deficiency anemia: 6.2% None

randomized controlled trial 26 weeks

Comparative evaluation between two nutritional supplements in the improvement of telogen effluvium.

Dose: recommended daily intake amounts; taken orally for 180 days so với: Placebo Hiệu quả: Group 1 trichoscopy improvement 11.09% vs Group 2 7.76% after 180 days (significant for Group 1 only P<0.05 for clinical parameters

Key Statistics

Nghiên cứu

7126

Người tham gia

↔

Mixed

Xếp hạng

Referenced Papers

Retrospective Review of 2851 Female Patients With Telogen Effluvium: A Single-Center Experience. Other

Journal of cosmetic … 2025 4 trích dẫn

Safety First: A Comprehensive Review of Nutritional Supplements for Hair Loss in Breast Cancer Patients. Review

Nutrients 2025 2 trích dẫn

Evaluation of the relationship of digital phototrichogram findings of patients with diffuse hair loss with blood TSH, ferritin and vitamin … Other

Northern clinics of … 2024 1 trích dẫn

Micronutrient Deficiencies and Digital Computerized Phototrichogram Analysis in Telogen Effluvium: a Retrospective Correlation Study in a Tertiary Medical Center. Other

Dermatology practical & … 2023 4 trích dẫn

Telogen effluvium in daily practice: Patient characteristics, laboratory parameters, and treatment modalities of 3028 patients with telogen effluvium. Other

Journal of cosmetic … 2022 22 trích dẫn

Cystine-thiamin-containing hair-growth formulation modulates the response to UV radiation in an in vitro model for growth-limiting conditions of human keratinocytes. Other

Journal of photochemistry … 2018 16 trích dẫn

Comparative evaluation between two nutritional supplements in the improvement of telogen effluvium. Other

Clinical, cosmetic and … 2018 16 trích dẫn

Vitamin and Mineral Deficiencies in Patients With Telogen Effluvium: A Retrospective Cross-Sectional Study. Other

Journal of drugs … 2016 56 trích dẫn

Trichotillomania: Bizzare Patern of Hair Loss at 11-Year-old Girl. Case Report

Acta dermatovenerologica Croatica … 2016 6 trích dẫn

The role of psychological factors and serum zinc, folate and vitamin B12 levels in the aetiology of trichodynia: a case-control … Other

Clinical and experimental … 2009 34 trích dẫn

Management of hair loss in women. Review

Dermatologic clinics 1993 38 trích dẫn

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Liều lượng thường dùng

general:: 400 mcg DFE/day

Giới hạn trên: 1,000 mcg/day (synthetic folic acid)

Liều lượng đã nghiên cứu

Liều lượng	Thời gian	Hiệu quả	N
None	--	Neutral	2851
None	--	Mixed	--
None	--	Mixed	108
None	--	Positive	973
standard replacement doses	--	Neutral	3028
recommended daily intake amounts; taken orally for 180 days	26 weeks	Positive	--
psychiatric and dermatological management	--	Neutral	1
None	--	Negative	--

Thời điểm dùng tốt nhất: With meals for better absorption

Safety & Side Effects

Tác dụng phụ đã được báo cáo

⚠ Generally well tolerated
⚠ May mask vitamin B12 deficiency symptoms at high doses
⚠ Rare: abdominal cramps, insomnia

Tương tác đã biết

● Methotrexate (folate antagonist; consult physician)
● Anticonvulsants (phenytoin, carbamazepine) may reduce folate levels
● Sulfasalazine (reduces folate absorption)

Mức hấp thụ tối đa cho phép: 1,000 mcg/day (synthetic folic acid)

Luôn tham khảo ý kiến bác sĩ trước khi bắt đầu sử dụng bất kỳ thực phẩm bổ sung nào.Luôn tham khảo ý kiến chuyên gia y tế trước khi sử dụng bất kỳ thực phẩm chức năng nào.

Frequently Asked Questions

Does Folate help with Telogen Effluvium?

Based on 10 studies with 7,126 participants, there is moderate evidence from clinical studies that Folate may support Telogen Effluvium management. Our evidence grade is B (Good Evidence).

How much Folate should I take for Telogen Effluvium?

Studies have used various dosages. A commonly studied range is 400 mcg DFE/day. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Folate?

Reported side effects may include Generally well tolerated, May mask vitamin B12 deficiency symptoms at high doses, Rare: abdominal cramps, insomnia. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Folate and Telogen Effluvium?

We rate the evidence as Grade B (Good Evidence). This rating is based on 10 peer-reviewed studies with 7,126 total participants. The overall direction of effect is mixed.

Các thành phần khác cho Telogen Effluvium

Minoxidil A Dầu Hạt Đen A Viviscal A Sắt B Keratin B Axit Béo Omega-3 B

Folate cho các tình trạng khác

Rụng Tóc Do Thiếu Dinh Dưỡng F

Đánh giá nhanh

Dựa trên 6 nghiên cứu với 4,166 người tham gia. Kết quả nghiên cứu không đồng nhất.

Evidence Strength72%

High confidence

Phân tích nghiên cứu

RCT (0)Meta (0)Other (10)

So sánh lựa chọn thay thế

Xem các thành phần khác so sánh như thế nào cho tình trạng này.

Xem tất cả thành phần cho Telogen Effluvium

Tìm hiểu thêm

References

[1] Ömer Karakoyun et al.. J Cosmet Dermatol. 2025. Retrospective Review of 2851 Female Patients With Telogen Effluvium: A Single-Center Experience. doi:10.1111/jocd.70037 PubMed
[2] Andrea Sechi et al.. Nutrients. 2025. Safety First: A Comprehensive Review of Nutritional Supplements for Hair Loss in Breast Cancer Patients. doi:10.3390/nu17091451 PubMed
[3] Leyla Bilik et al.. North Clin Istanb. 2024. Evaluation of the relationship of digital phototrichogram findings of patients with diffuse hair loss with blood TSH, ferritin and vitamin … doi:10.14744/nci.2023.33269 PubMed
[4] Hakan Arslan et al.. Dermatol Pract Concept. 2023. Micronutrient Deficiencies and Digital Computerized Phototrichogram Analysis in Telogen Effluvium: a Retrospective Correlation Study in a Tertiary Medical Center. doi:10.5826/dpc.1303a202 PubMed
[5] Ahu Yorulmaz et al.. J Cosmet Dermatol. 2022. Telogen effluvium in daily practice: Patient characteristics, laboratory parameters, and treatment modalities of 3028 patients with telogen effluvium. doi:10.1111/jocd.14413 PubMed
[6] Thomas Hengl et al.. J Photochem Photobiol B. 2018. Cystine-thiamin-containing hair-growth formulation modulates the response to UV radiation in an in vitro model for growth-limiting conditions of human keratinocytes. doi:10.1016/j.jphotobiol.2018.09.005 PubMed
[7] Flávia Alvim Sant'Anna Addor et al.. Clin Cosmet Investig Dermatol. 2018. Comparative evaluation between two nutritional supplements in the improvement of telogen effluvium. doi:10.2147/CCID.S173082 PubMed
[8] Evelyn J Cheung et al.. J Drugs Dermatol. 2016. Vitamin and Mineral Deficiencies in Patients With Telogen Effluvium: A Retrospective Cross-Sectional Study. PubMed
[9] Jana Zímová et al.. Acta Dermatovenerol Croat. 2016. Trichotillomania: Bizzare Patern of Hair Loss at 11-Year-old Girl. PubMed
[10] C Durusoy et al.. Clin Exp Dermatol. 2009. The role of psychological factors and serum zinc, folate and vitamin B12 levels in the aetiology of trichodynia: a case-control … doi:10.1111/j.1365-2230.2008.03165.x PubMed
[11] D H Rushton. Dermatol Clin. 1993. Management of hair loss in women. PubMed

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