Kẽm cho Telogen Effluvium

F Hiệu quả Nghiên cứu cho thấy điều này khó có khả năng hiệu quả cho mục đích sử dụng này.

Dựa trên 29 nghiên cứu (3 RCTs) với 30,246 người tham gia. Kết quả nghiên cứu không đồng nhất.

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Kết luận

Moderate evidence suggests that zinc deficiency may contribute to telogen effluvium, and supplementation may help if levels are low — but routine zinc supplementation for hair shedding is not clearly supported.

Lower zinc levels are frequently found in telogen effluvium patients
Some RCTs show benefits from zinc-containing supplement combinations
Difficult to isolate zinc's specific effect from multi-ingredient formulas
Testing zinc levels and supplementing only if deficient is a reasonable approach

Key Study Findings

Prospective Open-Label Interventional Study n=343 4 weeks Open-label

Effect of a Hydrolyzed Collagen, Vitamin, and Zinc Containing Nutritional Supplement on Telogen Effluvium.

Dose: Pilopeptan Intensive (hydrolyzed collagen, Group B vitamins, zinc); daily for 1 month so với: Placebo Hiệu quả: Significant improvements in all hair parameters at T1 and T2 (P < 0.001) p<0.001

Retrospective Cross-Sectional Study n=23975

Hair Loss and Zinc Deficiency: A Cross-Sectional Study.

Dose: None so với: Placebo Hiệu quả: Median zinc 96 µg/dL (hair loss) vs 99 µg/dL (control); statistically significant but clinically min p<0.001

cross-sectional study

Zinc Status in Kurdish Adults With Hair Loss.

Dose: None so với: Placebo Hiệu quả: None None

Case-Control Study n=100

Role of zinc in chronic telogen effluvium in serum and hair of patients with alopecia.

Dose: None so với: Placebo Hiệu quả: None 0.05

case-control study n=180

A comprehensive investigation of biochemical status in patients with telogen effluvium: Analysis of Hb, ferritin, …

Dose: not applicable so với: Placebo Hiệu quả: None None

Case-control n=100

Post Covid telogen effluvium: the diagnostic value of serum ferritin biomarker and the preventive value …

Dose: None so với: Placebo Hiệu quả: None None

Key Statistics

Nghiên cứu

30246

Người tham gia

↔

Mixed

Xếp hạng

Referenced Papers

Effect of a Hydrolyzed Collagen, Vitamin, and Zinc Containing Nutritional Supplement on Telogen Effluvium. Other

International journal of … 2025

Hair Loss and Zinc Deficiency: A Cross-Sectional Study. Other

Healthcare (Basel, Switzerland) 2025

A comprehensive investigation of biochemical status in patients with telogen effluvium: Analysis of Hb, ferritin, vitamin B12, vitamin D, thyroid … Other

Journal of cosmetic … 2024 7 trích dẫn

Post Covid telogen effluvium: the diagnostic value of serum ferritin biomarker and the preventive value of dietary supplements. a case … Other

Archives of dermatological … 2024 5 trích dẫn

Role of zinc in chronic telogen effluvium in serum and hair of patients with alopecia. Other

JPMA. The Journal … 2024 2 trích dẫn

Cost-effectiveness analysis of laboratory monitoring in newly diagnosed telogen effluvium patients. Other

Archives of dermatological … 2024 1 trích dẫn

Zinc Status in Kurdish Adults With Hair Loss. Other

Cureus 2024 1 trích dẫn

"Shedding" low yield testing for telogen effluvium: A cross-sectional study of 16,381 laboratory results from newly diagnosed patients. Other

Journal of the … 2023 5 trích dẫn

Micronutrient Deficiencies and Digital Computerized Phototrichogram Analysis in Telogen Effluvium: a Retrospective Correlation Study in a Tertiary Medical Center. Other

Dermatology practical & … 2023 4 trích dẫn

Clinical study on the efficacy and tolerability of an oral supplement based on arginine, l-cystine, zinc and B6 vitamin (Cystiphane®) … Other

Italian journal of … 2023 4 trích dẫn

Oral supplementation in female telogen effluvium: a clinical and instrumental objective evidence of efficacy and tolerability of new oral cosmetic … Other

Italian journal of … 2023 3 trích dẫn

Telogen effluvium in daily practice: Patient characteristics, laboratory parameters, and treatment modalities of 3028 patients with telogen effluvium. Other

Journal of cosmetic … 2022 22 trích dẫn

The role of micronutrients in the management of COIVD-19 and optimizing vaccine efficacy. Review

Human nutrition & … 2022 9 trích dẫn

Supplementation and hair growth: A retrospective chart review of patients with alopecia and laboratory abnormalities. Other

JAAD international 2022 6 trích dẫn

Possible relationship between poor skin disorders prognosis and serum zinc level: A narrative review. Other

Dermatology reports 2022 4 trích dẫn

A new combination of molecules for the treatment of androgenetic alopecia and telogen effluvium: a double-blind randomized, monocentric, placebo-controlled study. RCT

Italian journal of … 2022 2 trích dẫn

Laboratory Testing in Telogen Effluvium. Other

Journal of drugs … 2021 3 trích dẫn

Comparative evaluation between two nutritional supplements in the improvement of telogen effluvium. Other

Clinical, cosmetic and … 2018 16 trích dẫn

Assessment of Heavy Metal and Trace Element Levels in Patients with Telogen Effluvium. Other

Indian journal of … 2018 14 trích dẫn

Prevalence of Nutritional Deficiencies in Hair Loss among Indian Participants: Results of a Cross-sectional Study. Other

International journal of … 2017 43 trích dẫn

Vitamin and Mineral Deficiencies in Patients With Telogen Effluvium: A Retrospective Cross-Sectional Study. Other

Journal of drugs … 2016 56 trích dẫn

Female Pattern Hair Loss: A Retrospective Study in a Tertiary Referral Center. Other

International journal of … 2016 28 trích dẫn

Trichotillomania: Bizzare Patern of Hair Loss at 11-Year-old Girl. Case Report

Acta dermatovenerologica Croatica … 2016 6 trích dẫn

Possible Relationship between Chronic Telogen Effluvium and Changes in Lead, Cadmium, Zinc, and Iron Total Blood Levels in Females: A … Other

International journal of … 2015 18 trích dẫn

Use of Vitamins and Minerals in the Treatment of Hair Loss: A Cross-Sectional Survey among Dermatologists in Saudi Arabia. Other

Journal of cutaneous … 2014 10 trích dẫn

Analysis of serum zinc and copper concentrations in hair loss. Other

Annals of dermatology 2013 114 trích dẫn

Hair loss in children: common and uncommon causes; clinical and epidemiological study in jordan. Other

International journal of … 2013 37 trích dẫn

Oral zinc therapy for zinc deficiency-related telogen effluvium. Case Report

Dermatologic therapy 2012 31 trích dẫn

The role of psychological factors and serum zinc, folate and vitamin B12 levels in the aetiology of trichodynia: a case-control … Other

Clinical and experimental … 2009 34 trích dẫn

The diagnosis and treatment of iron deficiency and its potential relationship to hair loss. Review

Journal of the … 2006 255 trích dẫn

Dermatologic signs in patients with eating disorders. Review

American journal of … 2005 140 trích dẫn

Nudging hair shedding by antidandruff shampoos. A comparison of 1% ketoconazole, 1% piroctone olamine and 1% zinc pyrithione formulations. Other

International journal of … 2002 53 trích dẫn

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Liều lượng thường dùng

general:: 8-11 mg/day
hairloss:: 15-30 mg/day

Giới hạn trên: 40 mg/day

Liều lượng đã nghiên cứu

Liều lượng	Thời gian	Hiệu quả	N
Pilopeptan Intensive (hydrolyzed collagen, Group B vitamins, zinc); daily for 1 month	4 weeks	Positive	343
None	--	Neutral	23975
None	--	Neutral	--
None	--	Negative	100
not applicable	--	Mixed	180
None	--	Mixed	100
None	--	Mixed	--
4 tablets daily (arginine, l-cystine, zinc, vitamin B6)	12 weeks	Positive	20

Thời điểm dùng tốt nhất: With meals to minimize stomach upset; separate from iron and calcium by 2 hours

Safety & Side Effects

Tác dụng phụ đã được báo cáo

⚠ Nausea and vomiting (especially on an empty stomach)
⚠ Metallic taste in the mouth
⚠ Copper depletion with chronic high-dose use
⚠ Headache and diarrhea

Tương tác đã biết

● Copper supplements (zinc inhibits copper absorption at doses >40 mg/day)
● Tetracycline and quinolone antibiotics (mutual absorption reduction)
● Penicillamine (zinc reduces absorption of this rheumatoid arthritis drug)

Mức hấp thụ tối đa cho phép: 40 mg/day

Luôn tham khảo ý kiến bác sĩ trước khi bắt đầu sử dụng bất kỳ thực phẩm bổ sung nào.Luôn tham khảo ý kiến chuyên gia y tế trước khi sử dụng bất kỳ thực phẩm chức năng nào.

Frequently Asked Questions

Does Kẽm help with Telogen Effluvium?

Based on 32 studies with 30,246 participants, there is insufficient evidence at this time that Kẽm may support Telogen Effluvium management. Our evidence grade is F (Evidence Against).

How much Kẽm should I take for Telogen Effluvium?

Studies have used various dosages. A commonly studied range is 8-11 mg/day. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Kẽm?

Reported side effects may include Nausea and vomiting (especially on an empty stomach), Metallic taste in the mouth, Copper depletion with chronic high-dose use, Headache and diarrhea. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Kẽm and Telogen Effluvium?

We rate the evidence as Grade F (Evidence Against). This rating is based on 32 peer-reviewed studies with 30,246 total participants. The overall direction of effect is mixed.

Các thành phần khác cho Telogen Effluvium

Minoxidil A Dầu Hạt Đen A Viviscal A Sắt B Keratin B Axit Béo Omega-3 B

Kẽm cho các tình trạng khác

Rụng Tóc Androgen A Alopecia Areata F

Đánh giá nhanh

Dựa trên 29 nghiên cứu (3 RCTs) với 30,246 người tham gia. Kết quả nghiên cứu không đồng nhất.

Evidence Strength10%

Low confidence

Phân tích nghiên cứu

RCT (1)Meta (0)Other (31)

So sánh lựa chọn thay thế

Xem các thành phần khác so sánh như thế nào cho tình trạng này.

Xem tất cả thành phần cho Telogen Effluvium

Tìm hiểu thêm

References

[1] Eva María Arias et al.. Int J Trichology. 2025. Effect of a Hydrolyzed Collagen, Vitamin, and Zinc Containing Nutritional Supplement on Telogen Effluvium. doi:10.4103/ijt.ijt_70_24 PubMed
[2] Ori Liran et al.. Healthcare (Basel). 2025. Hair Loss and Zinc Deficiency: A Cross-Sectional Study. doi:10.3390/healthcare13222965 PubMed
[3] Irem Nur Durusu Turkoglu et al.. J Cosmet Dermatol. 2024. A comprehensive investigation of biochemical status in patients with telogen effluvium: Analysis of Hb, ferritin, vitamin B12, vitamin D, thyroid … doi:10.1111/jocd.16512 PubMed
[4] Nermeen Ibrahim Bedair et al.. Arch Dermatol Res. 2024. Post Covid telogen effluvium: the diagnostic value of serum ferritin biomarker and the preventive value of dietary supplements. a case … doi:10.1007/s00403-024-03004-1 PubMed
[5] Shayan Zufishan et al.. J Pak Med Assoc. 2024. Role of zinc in chronic telogen effluvium in serum and hair of patients with alopecia. doi:10.47391/JPMA-DUHS-S10 PubMed
[6] Rhiannon C Miller et al.. Arch Dermatol Res. 2024. Cost-effectiveness analysis of laboratory monitoring in newly diagnosed telogen effluvium patients. doi:10.1007/s00403-024-02948-8 PubMed
[7] Hivi Mahmoud et al.. Cureus. 2024. Zinc Status in Kurdish Adults With Hair Loss. doi:10.7759/cureus.67264 PubMed
[8] Rhiannon C Miller et al.. J Am Acad Dermatol. 2023. "Shedding" low yield testing for telogen effluvium: A cross-sectional study of 16,381 laboratory results from newly diagnosed patients. doi:10.1016/j.jaad.2023.05.045 PubMed
[9] Hakan Arslan et al.. Dermatol Pract Concept. 2023. Micronutrient Deficiencies and Digital Computerized Phototrichogram Analysis in Telogen Effluvium: a Retrospective Correlation Study in a Tertiary Medical Center. doi:10.5826/dpc.1303a202 PubMed
[10] Michela Starace et al.. Ital J Dermatol Venerol. 2023. Clinical study on the efficacy and tolerability of an oral supplement based on arginine, l-cystine, zinc and B6 vitamin (Cystiphane®) … doi:10.23736/S2784-8671.23.07576-X PubMed
[11] Michela Starace et al.. Ital J Dermatol Venerol. 2023. Oral supplementation in female telogen effluvium: a clinical and instrumental objective evidence of efficacy and tolerability of new oral cosmetic … doi:10.23736/S2784-8671.22.07416-3 PubMed
[12] Ahu Yorulmaz et al.. J Cosmet Dermatol. 2022. Telogen effluvium in daily practice: Patient characteristics, laboratory parameters, and treatment modalities of 3028 patients with telogen effluvium. doi:10.1111/jocd.14413 PubMed
[13] Noor Altooq et al.. Hum Nutr Metab. 2022. The role of micronutrients in the management of COIVD-19 and optimizing vaccine efficacy. doi:10.1016/j.hnm.2022.200141 PubMed
[14] Elizabeth J Klein et al.. JAAD Int. 2022. Supplementation and hair growth: A retrospective chart review of patients with alopecia and laboratory abnormalities. doi:10.1016/j.jdin.2022.08.013 PubMed
[15] Mohammed Al Abadie et al.. Dermatol Reports. 2022. Possible relationship between poor skin disorders prognosis and serum zinc level: A narrative review. doi:10.4081/dr.2022.9512 PubMed
[16] Alfredo Rossi et al.. Ital J Dermatol Venerol. 2022. A new combination of molecules for the treatment of androgenetic alopecia and telogen effluvium: a double-blind randomized, monocentric, placebo-controlled study. doi:10.23736/S2784-8671.21.06915-7 PubMed
[17] Efe Kakpovbia et al.. J Drugs Dermatol. 2021. Laboratory Testing in Telogen Effluvium. doi:10.36849/JDD.5771 PubMed
[18] Flávia Alvim Sant'Anna Addor et al.. Clin Cosmet Investig Dermatol. 2018. Comparative evaluation between two nutritional supplements in the improvement of telogen effluvium. doi:10.2147/CCID.S173082 PubMed
[19] Ibrahim Halil Yavuz et al.. Indian J Dermatol. 2018. Assessment of Heavy Metal and Trace Element Levels in Patients with Telogen Effluvium. doi:10.4103/ijd.IJD_610_17 PubMed
[20] Dinesh Gowda et al.. Int J Trichology. 2017. Prevalence of Nutritional Deficiencies in Hair Loss among Indian Participants: Results of a Cross-sectional Study. doi:10.4103/ijt.ijt_48_16 PubMed
[21] Evelyn J Cheung et al.. J Drugs Dermatol. 2016. Vitamin and Mineral Deficiencies in Patients With Telogen Effluvium: A Retrospective Cross-Sectional Study. PubMed
[22] Tee Wei Siah et al.. Int J Trichology. 2016. Female Pattern Hair Loss: A Retrospective Study in a Tertiary Referral Center. doi:10.4103/0974-7753.188033 PubMed
[23] Jana Zímová et al.. Acta Dermatovenerol Croat. 2016. Trichotillomania: Bizzare Patern of Hair Loss at 11-Year-old Girl. PubMed
[24] Abeer M Abdel Aziz et al.. Int J Trichology. 2015. Possible Relationship between Chronic Telogen Effluvium and Changes in Lead, Cadmium, Zinc, and Iron Total Blood Levels in Females: A … doi:10.4103/0974-7753.167465 PubMed
[25] Thamer Mubki. J Cutan Med Surg. 2014. Use of Vitamins and Minerals in the Treatment of Hair Loss: A Cross-Sectional Survey among Dermatologists in Saudi Arabia. doi:10.2310/7750.2014.14008 PubMed
[26] Min Seong Kil et al.. Ann Dermatol. 2013. Analysis of serum zinc and copper concentrations in hair loss. doi:10.5021/ad.2013.25.4.405 PubMed
[27] Khitam Al-Refu. Int J Trichology. 2013. Hair loss in children: common and uncommon causes; clinical and epidemiological study in jordan. doi:10.4103/0974-7753.130393 PubMed
[28] Tadashi Karashima et al.. Dermatol Ther. 2012. Oral zinc therapy for zinc deficiency-related telogen effluvium. doi:10.1111/j.1529-8019.2012.01443.x PubMed
[29] C Durusoy et al.. Clin Exp Dermatol. 2009. The role of psychological factors and serum zinc, folate and vitamin B12 levels in the aetiology of trichodynia: a case-control … doi:10.1111/j.1365-2230.2008.03165.x PubMed
[30] Leonid Benjamin Trost et al.. J Am Acad Dermatol. 2006. The diagnosis and treatment of iron deficiency and its potential relationship to hair loss. doi:10.1016/j.jaad.2005.11.1104 PubMed
[31] Renata Strumia. Am J Clin Dermatol. 2005. Dermatologic signs in patients with eating disorders. doi:10.2165/00128071-200506030-00003 PubMed
[32] C Piérard-Franchimont et al.. Int J Cosmet Sci. 2002. Nudging hair shedding by antidandruff shampoos. A comparison of 1% ketoconazole, 1% piroctone olamine and 1% zinc pyrithione formulations. doi:10.1046/j.1467-2494.2002.00145.x PubMed

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