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Zinc para Telogen Effluvium

F

Basado en 29 estudios (3 RCTs) con 30,246 participantes en total. Los resultados son variados entre los estudios.

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F

Conclusión

Moderate evidence suggests that zinc deficiency may contribute to telogen effluvium, and supplementation may help if levels are low — but routine zinc supplementation for hair shedding is not clearly supported.

  • Lower zinc levels are frequently found in telogen effluvium patients
  • Some RCTs show benefits from zinc-containing supplement combinations
  • Difficult to isolate zinc's specific effect from multi-ingredient formulas
  • Testing zinc levels and supplementing only if deficient is a reasonable approach

Key Study Findings

Prospective Open-Label Interventional Study n=343 4 weeks Open-label
Effect of a Hydrolyzed Collagen, Vitamin, and Zinc Containing Nutritional Supplement on Telogen Effluvium.
Dose: Pilopeptan Intensive (hydrolyzed collagen, Group B vitamins, zinc); daily for 1 month vs: Placebo Efecto: Significant improvements in all hair parameters at T1 and T2 (P < 0.001) p<0.001
Retrospective Cross-Sectional Study n=23975
Hair Loss and Zinc Deficiency: A Cross-Sectional Study.
Dose: None vs: Placebo Efecto: Median zinc 96 µg/dL (hair loss) vs 99 µg/dL (control); statistically significant but clinically min p<0.001
cross-sectional study
Zinc Status in Kurdish Adults With Hair Loss.
Dose: None vs: Placebo Efecto: None None
Case-Control Study n=100
Role of zinc in chronic telogen effluvium in serum and hair of patients with alopecia.
Dose: None vs: Placebo Efecto: None 0.05

Key Statistics

32

Estudios

30246

Participantes

Mixed

F

Calificación

Referenced Papers

Healthcare (Basel, Switzerland) 2025
Journal of drugs … 2021 3 citas
Acta dermatovenerologica Croatica … 2016 6 citas
Annals of dermatology 2013 114 citas
Dermatologic therapy 2012 31 citas
American journal of … 2005 140 citas

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Dosificaciones de uso común

general:
8-11 mg/day
hairloss:
15-30 mg/day

Límite superior: 40 mg/day

Dosificaciones estudiadas en la investigación

Dosificación Duración Efecto N
Pilopeptan Intensive (hydrolyzed collagen, Group B vitamins, zinc); daily for 1 month 4 weeks Positive 343
None -- Neutral 23975
None -- Neutral --
None -- Negative 100
not applicable -- Mixed 180
None -- Mixed 100
None -- Mixed --
4 tablets daily (arginine, l-cystine, zinc, vitamin B6) 12 weeks Positive 20

Mejor momento para tomar: With meals to minimize stomach upset; separate from iron and calcium by 2 hours

Safety & Side Effects

Efectos secundarios reportados

  • Nausea and vomiting (especially on an empty stomach)
  • Metallic taste in the mouth
  • Copper depletion with chronic high-dose use
  • Headache and diarrhea

Interacciones conocidas

  • Copper supplements (zinc inhibits copper absorption at doses >40 mg/day)
  • Tetracycline and quinolone antibiotics (mutual absorption reduction)
  • Penicillamine (zinc reduces absorption of this rheumatoid arthritis drug)

Ingesta máxima tolerable: 40 mg/day

Consulte siempre a su profesional de salud antes de comenzar cualquier suplemento.Siempre consulte a su profesional de salud antes de comenzar cualquier suplemento.

Frequently Asked Questions

Does Zinc help with Telogen Effluvium?
Based on 32 studies with 30,246 participants, there is insufficient evidence at this time that Zinc may support Telogen Effluvium management. Our evidence grade is F (Evidence Against).
How much Zinc should I take for Telogen Effluvium?
Studies have used various dosages. A commonly studied range is 8-11 mg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Zinc?
Reported side effects may include Nausea and vomiting (especially on an empty stomach), Metallic taste in the mouth, Copper depletion with chronic high-dose use, Headache and diarrhea. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Zinc and Telogen Effluvium?
We rate the evidence as Grade F (Evidence Against). This rating is based on 32 peer-reviewed studies with 30,246 total participants. The overall direction of effect is mixed.

Related Evidence

Aviso legal FDA: Estas declaraciones no han sido evaluadas por la Food and Drug Administration. Los productos y la información en este sitio web no están destinados a diagnosticar, tratar, curar ni prevenir ninguna enfermedad. Las calificaciones de evidencia presentadas se basan en nuestro análisis de investigación publicada revisada por pares y no constituyen consejo médico. Siempre consulte a su profesional de salud antes de comenzar cualquier régimen de suplementos.