Zinc para Alopecia Androgenética
A Evidencia Múltiples ensayos clínicos de gran tamaño muestran de forma consistente beneficios significativos.Basado en 29 estudios (1 meta-analysis, 3 RCTs) con 49,138 participantes en total. Los resultados son variados entre los estudios.
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A
Conclusión
Research on zinc for androgenetic alopecia is mixed — while zinc is important for hair follicle health, supplementation alone has not been clearly shown to improve pattern hair loss.
- Mixed results across 29 studies, including a meta-analysis showing inconsistent findings
- Some studies find lower zinc in people with pattern hair loss, others do not
- Zinc is usually studied as part of multi-ingredient formulas, making its individual contribution unclear
- Supplementation may only help if a zinc deficiency is confirmed
Key Study Findings
animal study
Protective mechanisms of zinc and/or selenium supplementation against BPA-induced male and offspring reproductive toxicity: Insights …
Dose: zinc and/or selenium supplementation; doses not specified in abstract
vs: Placebo
Efecto: None
None
Review
Minerals and Trace Elements: Key Protectors of Skin Health and Defenders against Skin Disorders.
Dose: None
vs: Placebo
Efecto: None
None
review
[Nutrition in improving sleep quality and fighting insomnia].
Dose: tryptophan, carbohydrates, omega-3, vitamins (B6, B12, folate, niacin, D, C, beta-carotene), mineral
vs: Placebo
Efecto: None
None
cross-sectional study
Zinc Status in Kurdish Adults With Hair Loss.
Dose: None
vs: Placebo
Efecto: None
None
systematic_review
Micronutrients and Androgenetic Alopecia: A Systematic Review.
Dose: variable across included studies
vs: Placebo
Efecto: vitamin B, D, iron, zinc deficiencies associated with increased AGA risk; supplementation showed pot
None
in vitro study
Regulatory Effects of Thai Rice By-Product Extracts from Oryza sativa L. cv. Bue Bang 3 …
Dose: not specified
vs: Placebo
Efecto: melanin production 130.18 ± 9.13% of control; NO secretion 1.43 ± 0.05 µM
p > 0.05 (vs theophylline, no
Key Statistics
33
Estudios
49138
Participantes
↔
Mixed
A
Calificación
Referenced Papers
Environment international
2026
Minerals and Trace Elements: Key Protectors of Skin Health and Defenders against Skin Disorders.
Review
Current medicinal chemistry
2025
5 citas
Biomedicine & pharmacotherapy …
2025
4 citas
Nutricion hospitalaria
2025
Micronutrients and Androgenetic Alopecia: A Systematic Review.
Systematic Review
Molecular nutrition & …
2024
7 citas
Cureus
2024
1 citas
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2023
108 citas
Theranostics
2023
65 citas
Plants (Basel, Switzerland)
2023
14 citas
Italian journal of …
2023
3 citas
European journal of …
2022
34 citas
Journal of cosmetic …
2022
11 citas
Human nutrition & …
2022
9 citas
JAAD international
2022
6 citas
Association between serum zinc levels and androgenetic alopecia: a systematic review and meta-analysis.
Meta-Analysis
Journal of cosmetic …
2022
5 citas
Dermatology reports
2022
4 citas
Italian journal of …
2022
2 citas
International journal of …
2021
23 citas
Annales de dermatologie …
2021
4 citas
Diagnostics (Basel, Switzerland)
2020
13 citas
Pharmacological reports : …
2020
7 citas
Skinmed
2020
Female Pattern Hair Loss and Androgen Excess: A Report From the Multidisciplinary Androgen Excess and PCOS Committee.
Meta-Analysis
The Journal of …
2019
101 citas
Journal of cosmetic …
2019
15 citas
Indian journal of …
2018
26 citas
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2017
43 citas
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2017
12 citas
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2017
10 citas
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2016
28 citas
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2016
6 citas
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2015
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International journal of …
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Clinical and experimental …
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140 citas
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
Dosificaciones de uso común
- general:
- 8-11 mg/day
- hairloss:
- 15-30 mg/day
Límite superior: 40 mg/day
Dosificaciones estudiadas en la investigación
| Dosificación | Duración | Efecto | N |
|---|---|---|---|
| zinc and/or selenium supplementation; doses not specified in abstract | -- | Positive | -- |
| None | -- | Positive | -- |
| tryptophan, carbohydrates, omega-3, vitamins (B6, B12, folate, niacin, D, C, beta-carotene), mineral | -- | Positive | -- |
| None | -- | Neutral | -- |
| variable across included studies | -- | Mixed | -- |
| not specified | -- | Positive | -- |
| Daily tablet (L-cystine, L-methionine, liposomal glutathione, zinc, copper, iron, selenium, ubidecar | 24 weeks | Positive | 20 |
| Topical lotion containing zinc and arginine (concentration not specified) | 23 weeks | Positive | 40 |
Mejor momento para tomar: With meals to minimize stomach upset; separate from iron and calcium by 2 hours
Safety & Side Effects
Efectos secundarios reportados
- ⚠ Nausea and vomiting (especially on an empty stomach)
- ⚠ Metallic taste in the mouth
- ⚠ Copper depletion with chronic high-dose use
- ⚠ Headache and diarrhea
Interacciones conocidas
- ● Copper supplements (zinc inhibits copper absorption at doses >40 mg/day)
- ● Tetracycline and quinolone antibiotics (mutual absorption reduction)
- ● Penicillamine (zinc reduces absorption of this rheumatoid arthritis drug)
Ingesta máxima tolerable: 40 mg/day
Consulte siempre a su profesional de salud antes de comenzar cualquier suplemento.Siempre consulte a su profesional de salud antes de comenzar cualquier suplemento.
Frequently Asked Questions
Does Zinc help with Alopecia Androgenética?
Based on 33 studies with 49,138 participants, there is strong evidence from multiple clinical trials that Zinc may support Alopecia Androgenética management. Our evidence grade is A (Strong Evidence).
How much Zinc should I take for Alopecia Androgenética?
Studies have used various dosages. A commonly studied range is 8-11 mg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Zinc?
Reported side effects may include Nausea and vomiting (especially on an empty stomach), Metallic taste in the mouth, Copper depletion with chronic high-dose use, Headache and diarrhea. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Zinc and Alopecia Androgenética?
We rate the evidence as Grade A (Strong Evidence). This rating is based on 33 peer-reviewed studies with 49,138 total participants. The overall direction of effect is mixed.
Related Evidence
Otros ingredientes para Alopecia Androgenética
Zinc para otras condiciones
References
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