아연 관련 안드로겐성 탈모증
A 근거 여러 대규모 임상 시험이 일관되게 유의미한 효과를 보여줍니다.총 49,138명의 참여자를 대상으로 한 29건의 연구(메타분석 1건, RCT 3건)에 근거합니다. 연구 결과는 혼재되어 있습니다.
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A
결론
Research on zinc for androgenetic alopecia is mixed — while zinc is important for hair follicle health, supplementation alone has not been clearly shown to improve pattern hair loss.
- Mixed results across 29 studies, including a meta-analysis showing inconsistent findings
- Some studies find lower zinc in people with pattern hair loss, others do not
- Zinc is usually studied as part of multi-ingredient formulas, making its individual contribution unclear
- Supplementation may only help if a zinc deficiency is confirmed
Key Study Findings
animal study
Protective mechanisms of zinc and/or selenium supplementation against BPA-induced male and offspring reproductive toxicity: Insights …
Dose: zinc and/or selenium supplementation; doses not specified in abstract
vs: Placebo
효과: None
None
Review
Minerals and Trace Elements: Key Protectors of Skin Health and Defenders against Skin Disorders.
Dose: None
vs: Placebo
효과: None
None
review
[Nutrition in improving sleep quality and fighting insomnia].
Dose: tryptophan, carbohydrates, omega-3, vitamins (B6, B12, folate, niacin, D, C, beta-carotene), mineral
vs: Placebo
효과: None
None
cross-sectional study
Zinc Status in Kurdish Adults With Hair Loss.
Dose: None
vs: Placebo
효과: None
None
systematic_review
Micronutrients and Androgenetic Alopecia: A Systematic Review.
Dose: variable across included studies
vs: Placebo
효과: vitamin B, D, iron, zinc deficiencies associated with increased AGA risk; supplementation showed pot
None
in vitro study
Regulatory Effects of Thai Rice By-Product Extracts from Oryza sativa L. cv. Bue Bang 3 …
Dose: not specified
vs: Placebo
효과: melanin production 130.18 ± 9.13% of control; NO secretion 1.43 ± 0.05 µM
p > 0.05 (vs theophylline, no
Key Statistics
33
연구
49138
참여자
↔
Mixed
A
등급
Referenced Papers
Environment international
2026
Minerals and Trace Elements: Key Protectors of Skin Health and Defenders against Skin Disorders.
Review
Current medicinal chemistry
2025
5 인용
Biomedicine & pharmacotherapy …
2025
4 인용
Nutricion hospitalaria
2025
Micronutrients and Androgenetic Alopecia: A Systematic Review.
Systematic Review
Molecular nutrition & …
2024
7 인용
Cureus
2024
1 인용
Bioactive materials
2023
108 인용
Theranostics
2023
65 인용
Plants (Basel, Switzerland)
2023
14 인용
Italian journal of …
2023
3 인용
European journal of …
2022
34 인용
Journal of cosmetic …
2022
11 인용
Human nutrition & …
2022
9 인용
JAAD international
2022
6 인용
Association between serum zinc levels and androgenetic alopecia: a systematic review and meta-analysis.
Meta-Analysis
Journal of cosmetic …
2022
5 인용
Dermatology reports
2022
4 인용
Italian journal of …
2022
2 인용
International journal of …
2021
23 인용
Annales de dermatologie …
2021
4 인용
Diagnostics (Basel, Switzerland)
2020
13 인용
Pharmacological reports : …
2020
7 인용
Skinmed
2020
Female Pattern Hair Loss and Androgen Excess: A Report From the Multidisciplinary Androgen Excess and PCOS Committee.
Meta-Analysis
The Journal of …
2019
101 인용
Journal of cosmetic …
2019
15 인용
Indian journal of …
2018
26 인용
International journal of …
2017
43 인용
Journal of research …
2017
12 인용
Indian journal of …
2017
10 인용
International journal of …
2016
28 인용
Acta dermatovenerologica Croatica …
2016
6 인용
Journal of ethnopharmacology
2015
37 인용
Journal of trace …
2014
62 인용
Journal of drugs …
2014
26 인용
Annals of dermatology
2013
114 인용
Clinical and experimental …
2009
34 인용
Georgian medical news
2007
Journal of the …
2006
255 인용
International journal of …
2002
53 인용
Clinical and experimental …
1989
140 인용
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
일반적으로 사용되는 용량
- general:
- 8-11 mg/day
- hairloss:
- 15-30 mg/day
상한량: 40 mg/day
연구에서 사용된 용량
| 용량 | 기간 | 효과 | N |
|---|---|---|---|
| zinc and/or selenium supplementation; doses not specified in abstract | -- | Positive | -- |
| None | -- | Positive | -- |
| tryptophan, carbohydrates, omega-3, vitamins (B6, B12, folate, niacin, D, C, beta-carotene), mineral | -- | Positive | -- |
| None | -- | Neutral | -- |
| variable across included studies | -- | Mixed | -- |
| not specified | -- | Positive | -- |
| Daily tablet (L-cystine, L-methionine, liposomal glutathione, zinc, copper, iron, selenium, ubidecar | 24 weeks | Positive | 20 |
| Topical lotion containing zinc and arginine (concentration not specified) | 23 weeks | Positive | 40 |
권장 복용 시간: With meals to minimize stomach upset; separate from iron and calcium by 2 hours
Safety & Side Effects
보고된 부작용
- ⚠ Nausea and vomiting (especially on an empty stomach)
- ⚠ Metallic taste in the mouth
- ⚠ Copper depletion with chronic high-dose use
- ⚠ Headache and diarrhea
알려진 상호작용
- ● Copper supplements (zinc inhibits copper absorption at doses >40 mg/day)
- ● Tetracycline and quinolone antibiotics (mutual absorption reduction)
- ● Penicillamine (zinc reduces absorption of this rheumatoid arthritis drug)
일일 최대 섭취 허용량: 40 mg/day
건강기능식품을 복용하기 전에 반드시 의료 전문가와 상담하십시오.
Frequently Asked Questions
Does 아연 help with 안드로겐성 탈모증?
Based on 33 studies with 49,138 participants, there is strong evidence from multiple clinical trials that 아연 may support 안드로겐성 탈모증 management. Our evidence grade is A (Strong Evidence).
How much 아연 should I take for 안드로겐성 탈모증?
Studies have used various dosages. A commonly studied range is 8-11 mg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of 아연?
Reported side effects may include Nausea and vomiting (especially on an empty stomach), Metallic taste in the mouth, Copper depletion with chronic high-dose use, Headache and diarrhea. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for 아연 and 안드로겐성 탈모증?
We rate the evidence as Grade A (Strong Evidence). This rating is based on 33 peer-reviewed studies with 49,138 total participants. The overall direction of effect is mixed.
Related Evidence
References
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