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아연 관련 원형 탈모증

F 효과 연구에 따르면 이 용도에 효과가 있을 가능성은 낮은 것으로 나타납니다.

총 23,495명의 참여자를 대상으로 한 46건의 연구(메타분석 3건, RCT 1건)에 근거합니다. 연구 결과는 혼재되어 있습니다.

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결론

While people with alopecia areata often have lower zinc levels, research is mixed on whether zinc supplementation helps — it may support overall immune health but is not a reliable solution for alopecia areata.

  • Lower zinc levels are consistently found in alopecia areata patients
  • Supplementation studies show inconsistent results for hair regrowth
  • Zinc plays a role in immune function, which is relevant to autoimmune hair loss
  • No large-scale RCT specifically tests zinc supplementation for alopecia areata

Key Study Findings

Review
Eyebrow Madarosis: An Updated Review of the Etiology and Management, Part I - Nonscarring Disorders.
Dose: None vs: None Outcome: None 효과: None None

대상 집단: review of nonscarring eyebrow alopecia etiologies and management (1960-2025)

Review
The role of trace elements for the function and health of the skin.
Dose: None vs: Placebo 효과: None None
Meta-Analysis n=4931
Association Between Serum Trace Elements Level and Alopecia Areata: A Systematic Review and Meta-Analysis.
Dose: None vs: Placebo 효과: SMD=-0.93 (vitamin D); SMD=-0.69 (zinc); OR=2.48 (vitamin D deficiency risk) p<0.05
Animal Study n=36
Associations between ionomic profile and metabolic abnormalities in a murine model of sodium sulfide induced …
Dose: Tofacitinib 1 mg/kg vs: Placebo 효과: Differential metabolites and ions identified via OPLS-DA; Mg2+ correlated with CD8+ T cell modulatio None
Systematic Review and Meta-Analysis n=7014
Trace Elements and Risk of Immune-Mediated Skin Disease: A Systematic Review and Meta-analysis.
Dose: None vs: Placebo 효과: Standardized mean differences reported for each element and disease combination (specific values not None

Key Statistics

60

연구

23876

참여자

Mixed

F

등급

Referenced Papers

Acta dermato-venereologica 2023 11 인용
Skin appendage disorders 2020 10 인용
The Australasian journal … 2019 51 인용
Indian journal of … 2019 10 인용
American journal of … 2017 104 인용
Archives of biochemistry … 2016 124 인용
Clinics in dermatology 2016 19 인용
Acta dermatovenerologica Croatica … 2016 6 인용
Annals of dermatology 2013 114 인용
Indian journal of … 2009 79 인용
Clinical and experimental … 2003 6 인용
Zeitschrift fur Hautkrankheiten 1987 3 인용
Giornale italiano di … 1986
Dermatologische Monatschrift 1984 3 인용
The British journal … 1981 58 인용
Zeitschrift fur Hautkrankheiten 1980
Przeglad dermatologiczny 1978 4 인용

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

일반적으로 사용되는 용량

general:
8-11 mg/day
hairloss:
15-30 mg/day

상한량: 40 mg/day

연구에서 사용된 용량

용량 기간 효과 N
None -- Neutral --
None -- Mixed --
None -- Negative 4931
None -- Positive --
Tofacitinib 1 mg/kg -- Positive 36
None -- Mixed 7014
None -- Neutral 30
Corticosteroid injections (dose not specified) in transgenic mice -- Positive --

권장 복용 시간: With meals to minimize stomach upset; separate from iron and calcium by 2 hours

Safety & Side Effects

보고된 부작용

  • Nausea and vomiting (especially on an empty stomach)
  • Metallic taste in the mouth
  • Copper depletion with chronic high-dose use
  • Headache and diarrhea

알려진 상호작용

  • Copper supplements (zinc inhibits copper absorption at doses >40 mg/day)
  • Tetracycline and quinolone antibiotics (mutual absorption reduction)
  • Penicillamine (zinc reduces absorption of this rheumatoid arthritis drug)

일일 최대 섭취 허용량: 40 mg/day

건강기능식품을 복용하기 전에 반드시 의료 전문가와 상담하십시오.

Frequently Asked Questions

Does 아연 help with 원형 탈모증?
Based on 60 studies with 23,876 participants, there is insufficient evidence at this time that 아연 may support 원형 탈모증 management. Our evidence grade is F (Evidence Against).
How much 아연 should I take for 원형 탈모증?
Studies have used various dosages. A commonly studied range is 8-11 mg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of 아연?
Reported side effects may include Nausea and vomiting (especially on an empty stomach), Metallic taste in the mouth, Copper depletion with chronic high-dose use, Headache and diarrhea. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for 아연 and 원형 탈모증?
We rate the evidence as Grade F (Evidence Against). This rating is based on 60 peer-reviewed studies with 23,876 total participants. The overall direction of effect is mixed.

References

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