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Zink für Alopecia Areata

F Wirkung Die Forschung zeigt, dass dies für diese Anwendung wahrscheinlich nicht wirksam ist.

Basierend auf 46 Studien (3 meta-analyses, 1 RCT) mit 23,495 Teilnehmern insgesamt. Die Ergebnisse sind uneinheitlich zwischen den Studien.

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F

Fazit

While people with alopecia areata often have lower zinc levels, research is mixed on whether zinc supplementation helps — it may support overall immune health but is not a reliable solution for alopecia areata.

  • Lower zinc levels are consistently found in alopecia areata patients
  • Supplementation studies show inconsistent results for hair regrowth
  • Zinc plays a role in immune function, which is relevant to autoimmune hair loss
  • No large-scale RCT specifically tests zinc supplementation for alopecia areata

Key Study Findings

Review
Eyebrow Madarosis: An Updated Review of the Etiology and Management, Part I - Nonscarring Disorders.
Dose: None vs.: None Outcome: None Wirkung: None None

Population: review of nonscarring eyebrow alopecia etiologies and management (1960-2025)

Review
The role of trace elements for the function and health of the skin.
Dose: None vs.: Placebo Wirkung: None None
Meta-Analysis n=4931
Association Between Serum Trace Elements Level and Alopecia Areata: A Systematic Review and Meta-Analysis.
Dose: None vs.: Placebo Wirkung: SMD=-0.93 (vitamin D); SMD=-0.69 (zinc); OR=2.48 (vitamin D deficiency risk) p<0.05
Animal Study n=36
Associations between ionomic profile and metabolic abnormalities in a murine model of sodium sulfide induced …
Dose: Tofacitinib 1 mg/kg vs.: Placebo Wirkung: Differential metabolites and ions identified via OPLS-DA; Mg2+ correlated with CD8+ T cell modulatio None
Systematic Review and Meta-Analysis n=7014
Trace Elements and Risk of Immune-Mediated Skin Disease: A Systematic Review and Meta-analysis.
Dose: None vs.: Placebo Wirkung: Standardized mean differences reported for each element and disease combination (specific values not None

Key Statistics

60

Studien

23876

Teilnehmer

Mixed

F

Bewertung

Referenced Papers

Journal of trace … 2025 4 Zitierungen
Cureus 2024 1 Zitierungen
Acta dermato-venereologica 2023 11 Zitierungen
Skin appendage disorders 2020 10 Zitierungen
The Australasian journal … 2019 51 Zitierungen
Indian journal of … 2019 10 Zitierungen
American journal of … 2017 104 Zitierungen
Archives of biochemistry … 2016 124 Zitierungen
Clinics in dermatology 2016 19 Zitierungen
Acta dermatovenerologica Croatica … 2016 6 Zitierungen
Journal of the … 2016 4 Zitierungen
Annals of dermatology 2013 114 Zitierungen
Indian journal of … 2009 79 Zitierungen
Clinical and experimental … 2003 6 Zitierungen
Zeitschrift fur Hautkrankheiten 1987 3 Zitierungen
Giornale italiano di … 1986
Dermatologische Monatschrift 1984 3 Zitierungen
The British journal … 1981 58 Zitierungen
Zeitschrift fur Hautkrankheiten 1980
Przeglad dermatologiczny 1978 4 Zitierungen

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Übliche Dosierungen

general:
8-11 mg/day
hairloss:
15-30 mg/day

Obergrenze: 40 mg/day

In der Forschung untersuchte Dosierungen

Dosierung Dauer Wirkung N
None -- Neutral --
None -- Mixed --
None -- Negative 4931
None -- Positive --
Tofacitinib 1 mg/kg -- Positive 36
None -- Mixed 7014
None -- Neutral 30
Corticosteroid injections (dose not specified) in transgenic mice -- Positive --

Beste Einnahmezeit: With meals to minimize stomach upset; separate from iron and calcium by 2 hours

Safety & Side Effects

Gemeldete Nebenwirkungen

  • Nausea and vomiting (especially on an empty stomach)
  • Metallic taste in the mouth
  • Copper depletion with chronic high-dose use
  • Headache and diarrhea

Bekannte Wechselwirkungen

  • Copper supplements (zinc inhibits copper absorption at doses >40 mg/day)
  • Tetracycline and quinolone antibiotics (mutual absorption reduction)
  • Penicillamine (zinc reduces absorption of this rheumatoid arthritis drug)

Tolerierbare Höchstaufnahmemenge: 40 mg/day

Konsultieren Sie immer Ihren Arzt, bevor Sie ein Nahrungsergänzungsmittel einnehmen.Konsultieren Sie immer Ihren Arzt, bevor Sie ein Nahrungsergänzungsmittel einnehmen.

Frequently Asked Questions

Does Zink help with Alopecia Areata?
Based on 60 studies with 23,876 participants, there is insufficient evidence at this time that Zink may support Alopecia Areata management. Our evidence grade is F (Evidence Against).
How much Zink should I take for Alopecia Areata?
Studies have used various dosages. A commonly studied range is 8-11 mg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Zink?
Reported side effects may include Nausea and vomiting (especially on an empty stomach), Metallic taste in the mouth, Copper depletion with chronic high-dose use, Headache and diarrhea. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Zink and Alopecia Areata?
We rate the evidence as Grade F (Evidence Against). This rating is based on 60 peer-reviewed studies with 23,876 total participants. The overall direction of effect is mixed.

References

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