마이크로니들링 관련 원형 탈모증

A 근거 여러 대규모 임상 시험이 일관되게 유의미한 효과를 보여줍니다.

총 1,908명의 참여자를 대상으로 한 32건의 연구(메타분석 1건, RCT 9건)에 근거합니다. 32건 중 25건의 연구에서 긍정적인 효과가 나타났습니다.

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결론

Microneedling has strong evidence for supporting hair regrowth in alopecia areata, especially when combined with topical medications, and is backed by multiple randomized controlled trials.

25 out of 32 studies show positive effects, with 9 RCTs providing robust evidence
Works by creating micro-injuries that stimulate healing responses and improve drug absorption
Most effective when combined with topical agents like corticosteroids or vitamin D3
Both professional clinical procedures and at-home derma rollers have been studied

Key Study Findings

scoping_review n=16

A Scoping Review of Exosome Delivery Applications in Hair Loss.

Dose: variable; exosomes predominantly from mesenchymal stem cells (MSCs) vs: Placebo 효과: None None

retrospective cohort n=7 Open-label

Combination Therapy With CGF and Microneedling-Assisted Compound Betamethasone for Resistant Alopecia Areata: A Pilot Study.

Dose: Concentrated growth factor (CGF) combined with microneedling-assisted compound betamethasone; multip vs: Placebo 효과: 85.7% achieved complete recovery; 14.3% achieved >50% regrowth; significant SALT score improvement None

Review

Technological Advances in Anti-hair Loss and Hair Regrowth Cosmeceuticals: Mechanistic Breakthroughs and Industrial Prospects Driven …

Dose: None vs: Placebo 효과: None None

randomized controlled trial n=24 18 weeks Open-label

A Comparative Clinical and Trichoscopic Study Between Fractional Radiofrequency Microneedling Versus Intralesional Steroids in Treatment …

Dose: Fractional radiofrequency microneedling (FRM), 6 sessions with 3-week intervals vs: Placebo 효과: Comparable efficacy between FRM and ILCS; nonsignificant differences in trichoscopic scores, PGA, an None

review

The role of microtrauma in hair regrowth and regeneration in non-scarring alopecia.

Dose: Various microtrauma procedures: microneedling, fractional/non-fractional lasers, contact immunothera vs: Placebo 효과: Positive outcomes reported for hair density and thickness with microneedling, lasers, LLLT, and PRP None

animal study 2 weeks

Investigating the potential mechanism of microneedling in alopecia areata mice based on 16S rRNA sequencing …

Dose: Halometasone topical applied every 2 days for 2 weeks after hand-held dermal microneedling treatment vs: Placebo 효과: Microneedling enhanced hair growth; restored gut microbiome diversity; reduced acetic acid and propa None

Key Statistics

연구

1908

참여자

↑

Positive

등급

Referenced Papers

A Scoping Review of Exosome Delivery Applications in Hair Loss. Review

Cureus 2025 7 인용

Technological Advances in Anti-hair Loss and Hair Regrowth Cosmeceuticals: Mechanistic Breakthroughs and Industrial Prospects Driven by Multidisciplinary Collaborative Innovation. Review

Aesthetic plastic surgery 2025 2 인용

Combination Therapy With CGF and Microneedling-Assisted Compound Betamethasone for Resistant Alopecia Areata: A Pilot Study. Other

Journal of cosmetic … 2025 1 인용

The role of microtrauma in hair regrowth and regeneration in non-scarring alopecia. Review

Italian journal of … 2025

Microinfusion of medications into the skin as a drug delivery technique: a narrative review. Other

Dermatology reports 2025

A Comparative Clinical and Trichoscopic Study Between Fractional Radiofrequency Microneedling Versus Intralesional Steroids in Treatment of Alopecia Areata. RCT

Dermatologic surgery : … 2025

Investigating the potential mechanism of microneedling in alopecia areata mice based on 16S rRNA sequencing and metabolomics. Other

Frontiers in microbiology 2025

The role of laser and energy-assisted drug delivery in the treatment of alopecia. Review

Lasers in medical … 2024 10 인용

Growth Factors and Microneedling in Alopecia Areata: A Narrative Review. Review

Skin appendage disorders 2024 5 인용

Comparison between melatonin versus melatonin and photobiomodulation versus photobiomodulation in the treatment of Alopecia X in German Spitz dogs: Clinical, … Other

PloS one 2024 4 인용

Effect of minoxidil combined with triamcinolone acetonide on alopecia areata by microneedle injection. Other

Skin research and … 2024 3 인용

Cosmetic filler-induced hair loss: case series and literature review. Case Report

The Journal of … 2024 2 인용

Combined microneedling with topical vitamin D3 or bimatoprost versus microneedling alone in the treatment of alopecia areata: A comparative randomized … RCT

Journal of cosmetic … 2023 8 인용

Efficacy, safety, and Pharmacoeconomics of Three Common Strategies for Pediatric Alopecia Areata Patients: A Retrospective Cohort Study. Other

Clinical, cosmetic and … 2023 3 인용

Microneedling and Its Use in Hair Loss Disorders: A Systematic Review. Review

Dermatology and therapy 2022 43 인용

Clinical efficacy of adipocyte-derived stem cells conditioned media combined with micro-injury in refractory patch of alopecia areata. Other

Archives of dermatological … 2022 16 인용

Efficacy of intradermal minoxidil 5% injections for treatment of patchy non-severe alopecia areata. RCT

The Journal of … 2022 9 인용

Fractional CO2 laser versus microneedling as a transepidermal drug delivery system for the treatment of alopecia areata: A clinical dermoscopic … RCT

Dermatologic therapy 2022 9 인용

Microneedling combined with compound betamethasone in treatment of severe alopecia areata: A case report. Case Report

Frontiers in immunology 2022 8 인용

Comparative study between topical application of triamcinolone acetonide after fractional carbon dioxide laser versus microneedling in the treatment of resistant … RCT

Dermatologic therapy 2022 8 인용

Comparative Efficacy of Injection Triamcinolone Acetonide given Intralesionally and through Microneedling in Alopecia areata. Other

International journal of … 2022 1 인용

Platelet Rich Plasma Hybridized Adipose Transplant (PHAT) for the Treatment of Hair Loss: A Case Series. Review

Aesthetic plastic surgery 2021 8 인용

Superficial cryotherapy using dimethyl ether and propane mixture versus microneedling in the treatment of alopecia areata: A prospective single-blinded randomized … RCT

Dermatologic therapy 2021 7 인용

Combination of photodynamic therapy with 5-aminolaevulinic acid and microneedling in the treatment of alopecia areata resistant to conventional therapies: our … Other

Clinical and experimental … 2020 27 인용

Platelet-rich plasma in alopecia areata: intradermal injection versus topical application with transepidermal delivery via either fractional carbon dioxide laser or … RCT

Acta dermatovenerologica Alpina, … 2020 24 인용

Adverse effects of platelet-rich plasma and microneedling. Other

Journal of the … 2020 10 인용

Ophiasis alopecia areata treated with microneedling. Case Report

Proceedings (Baylor University. … 2020 8 인용

Successful Treatment of Alopecia Areata Patches with Triamcinolone Acetonide Using MMP®: Report of 2 Cases. Case Report

Skin appendage disorders 2020 6 인용

Fractional Laser-assisted Hair Regrowth and Microneedling for the Treatment of Alopecia Areata: A Review. Review

Cureus 2019 18 인용

The rise of transcutaneous drug delivery for the management of alopecia: a review of existing literature and an eye towards … Review

Journal of cosmetic … 2019 14 인용

Microneedling for the treatment of hair loss? Review

Journal of the … 2018 114 인용

An Overview of the Biology of Platelet-Rich Plasma and Microneedling as Potential Treatments for Alopecia Areata. Review

The journal of … 2018 25 인용

WITHDRAWN: An Overview of the Biology of Platelet-Rich Plasma and Microneedling as Potential Treatments for Alopecia Areata. Review

The Journal of … 2017 1 인용

Alopecia areata-successful outcome with microneedling and triamcinolone acetonide. Other

Journal of cutaneous … 2014 80 인용

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

일반적으로 사용되는 용량

hairloss:: 1.5 mm depth, weekly sessions

상한량: Not applicable

연구에서 사용된 용량

용량	기간	효과	N
variable; exosomes predominantly from mesenchymal stem cells (MSCs)	--	Positive	16
Concentrated growth factor (CGF) combined with microneedling-assisted compound betamethasone; multip	--	Positive	7
None	--	Mixed	--
Fractional radiofrequency microneedling (FRM), 6 sessions with 3-week intervals	18 weeks	Neutral	24
Various microtrauma procedures: microneedling, fractional/non-fractional lasers, contact immunothera	--	Positive	--
Halometasone topical applied every 2 days for 2 weeks after hand-held dermal microneedling treatment	2 weeks	Positive	--
Microinfusion of medications into the skin (MMP) using tattoo devices; various drugs (minoxidil, ste	--	Positive	--
Melatonin 3 mg/kg; PBM diode laser 660nm, 100mW, 3 J/point, 2 sessions/week	12 weeks	Mixed	60

권장 복용 시간: Weekly sessions; avoid minoxidil for 24 hours post-treatment

Safety & Side Effects

보고된 부작용

⚠ Scalp redness and inflammation (24-72 hours)
⚠ Mild bleeding at treatment site
⚠ Scalp tenderness and soreness
⚠ Rare: infection if proper sterilization not maintained

알려진 상호작용

● Topical minoxidil (enhanced absorption; wait 24 hours after microneedling to apply)
● Blood thinners (may increase bleeding during procedure)
● Topical retinoids (discontinue 3-5 days before treatment)

일일 최대 섭취 허용량: Not applicable

건강기능식품을 복용하기 전에 반드시 의료 전문가와 상담하십시오.

Frequently Asked Questions

Does 마이크로니들링 help with 원형 탈모증?

Based on 34 studies with 1,908 participants, there is strong evidence from multiple clinical trials that 마이크로니들링 may support 원형 탈모증 management. Our evidence grade is A (Strong Evidence).

How much 마이크로니들링 should I take for 원형 탈모증?

Studies have used various dosages. A commonly studied range is 1.5 mm depth, weekly sessions. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of 마이크로니들링?

Reported side effects may include Scalp redness and inflammation (24-72 hours), Mild bleeding at treatment site, Scalp tenderness and soreness, Rare: infection if proper sterilization not maintained. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for 마이크로니들링 and 원형 탈모증?

We rate the evidence as Grade A (Strong Evidence). This rating is based on 34 peer-reviewed studies with 1,908 total participants. The overall direction of effect is positive.

마이크로니들링 다른 건강 상태에 대한 근거

안드로겐성 탈모증 A

한눈에 보기

총 1,908명의 참여자를 대상으로 한 32건의 연구(메타분석 1건, RCT 9건)에 근거합니다. 32건 중 25건의 연구에서 긍정적인 효과가 나타났습니다.

Evidence Strength92%

High confidence

연구 분석

RCT (7)Meta (0)Other (27)

대안 비교

이 건강 상태에 대한 다른 성분의 비교 결과를 확인하세요.

모든 성분 보기: 원형 탈모증

자세히 알아보기

References

[1] Sarah Schaffer et al.. Cureus. 2025. A Scoping Review of Exosome Delivery Applications in Hair Loss. doi:10.7759/cureus.81152 PubMed
[2] Xuexue Pan et al.. Aesthetic Plast Surg. 2025. Technological Advances in Anti-hair Loss and Hair Regrowth Cosmeceuticals: Mechanistic Breakthroughs and Industrial Prospects Driven by Multidisciplinary Collaborative Innovation. doi:10.1007/s00266-025-05077-3 PubMed
[3] Lingling Jia et al.. J Cosmet Dermatol. 2025. Combination Therapy With CGF and Microneedling-Assisted Compound Betamethasone for Resistant Alopecia Areata: A Pilot Study. doi:10.1111/jocd.16591 PubMed
[4] Woo C Tay et al.. Ital J Dermatol Venerol. 2025. The role of microtrauma in hair regrowth and regeneration in non-scarring alopecia. doi:10.23736/S2784-8671.25.08232-5 PubMed
[5] Khalid Nabil Nagshabandi et al.. Dermatol Reports. 2025. Microinfusion of medications into the skin as a drug delivery technique: a narrative review. doi:10.4081/dr.2025.10306 PubMed
[6] Eman Raafat Said et al.. Dermatol Surg. 2025. A Comparative Clinical and Trichoscopic Study Between Fractional Radiofrequency Microneedling Versus Intralesional Steroids in Treatment of Alopecia Areata. doi:10.1097/DSS.0000000000004619 PubMed
[7] Yue Zhang et al.. Front Microbiol. 2025. Investigating the potential mechanism of microneedling in alopecia areata mice based on 16S rRNA sequencing and metabolomics. doi:10.3389/fmicb.2025.1649496 PubMed
[8] Eliza Balazic et al.. Lasers Med Sci. 2024. The role of laser and energy-assisted drug delivery in the treatment of alopecia. doi:10.1007/s10103-024-04015-0 PubMed
[9] Malak M Almutlq et al.. Skin Appendage Disord. 2024. Growth Factors and Microneedling in Alopecia Areata: A Narrative Review. doi:10.1159/000534636 PubMed
[10] Flaviana Amado Martins et al.. PLoS One. 2024. Comparison between melatonin versus melatonin and photobiomodulation versus photobiomodulation in the treatment of Alopecia X in German Spitz dogs: Clinical, … doi:10.1371/journal.pone.0304605 PubMed
[11] Fanglin Wei et al.. Skin Res Technol. 2024. Effect of minoxidil combined with triamcinolone acetonide on alopecia areata by microneedle injection. doi:10.1111/srt.13713 PubMed
[12] Yutong Xie et al.. J Dermatolog Treat. 2024. Cosmetic filler-induced hair loss: case series and literature review. doi:10.1080/09546634.2024.2443111 PubMed
[13] Mona S Ali et al.. J Cosmet Dermatol. 2023. Combined microneedling with topical vitamin D3 or bimatoprost versus microneedling alone in the treatment of alopecia areata: A comparative randomized … doi:10.1111/jocd.15569 PubMed
[14] Jiong Zhou et al.. Clin Cosmet Investig Dermatol. 2023. Efficacy, safety, and Pharmacoeconomics of Three Common Strategies for Pediatric Alopecia Areata Patients: A Retrospective Cohort Study. doi:10.2147/CCID.S425534 PubMed
[15] Robert S English et al.. Dermatol Ther (Heidelb). 2022. Microneedling and Its Use in Hair Loss Disorders: A Systematic Review. doi:10.1007/s13555-021-00653-2 PubMed
[16] Seon Bok Lee et al.. Arch Dermatol Res. 2022. Clinical efficacy of adipocyte-derived stem cells conditioned media combined with micro-injury in refractory patch of alopecia areata. doi:10.1007/s00403-021-02252-9 PubMed
[17] Mahmoud Abd El-Rahim Abdallah et al.. J Dermatolog Treat. 2022. Efficacy of intradermal minoxidil 5% injections for treatment of patchy non-severe alopecia areata. doi:10.1080/09546634.2020.1793893 PubMed
[18] Faten Abd ElWadoud Abd ElKawy et al.. Dermatol Ther. 2022. Fractional CO2 laser versus microneedling as a transepidermal drug delivery system for the treatment of alopecia areata: A clinical dermoscopic … doi:10.1111/dth.15553 PubMed
[19] Danning Pei et al.. Front Immunol. 2022. Microneedling combined with compound betamethasone in treatment of severe alopecia areata: A case report. doi:10.3389/fimmu.2022.939077 PubMed
[20] Mai Mohamed Omar et al.. Dermatol Ther. 2022. Comparative study between topical application of triamcinolone acetonide after fractional carbon dioxide laser versus microneedling in the treatment of resistant … doi:10.1111/dth.15913 PubMed
[21] Astha Arora et al.. Int J Trichology. 2022. Comparative Efficacy of Injection Triamcinolone Acetonide given Intralesionally and through Microneedling in Alopecia areata. doi:10.4103/ijt.ijt_140_20 PubMed
[22] Benjamin Talei et al.. Aesthetic Plast Surg. 2021. Platelet Rich Plasma Hybridized Adipose Transplant (PHAT) for the Treatment of Hair Loss: A Case Series. doi:10.1007/s00266-021-02406-0 PubMed
[23] Soha Aboeldahab et al.. Dermatol Ther. 2021. Superficial cryotherapy using dimethyl ether and propane mixture versus microneedling in the treatment of alopecia areata: A prospective single-blinded randomized … doi:10.1111/dth.15044 PubMed
[24] C M Giorgio et al.. Clin Exp Dermatol. 2020. Combination of photodynamic therapy with 5-aminolaevulinic acid and microneedling in the treatment of alopecia areata resistant to conventional therapies: our … doi:10.1111/ced.14084 PubMed
[25] Sally Esam Marouf Ragab et al.. Acta Dermatovenerol Alp Pannonica Adriat. 2020. Platelet-rich plasma in alopecia areata: intradermal injection versus topical application with transepidermal delivery via either fractional carbon dioxide laser or … PubMed
[26] Olivera Stojadinovic et al.. J Am Acad Dermatol. 2020. Adverse effects of platelet-rich plasma and microneedling. doi:10.1016/j.jaad.2019.07.109 PubMed
[27] Usman Asad et al.. Proc (Bayl Univ Med Cent). 2020. Ophiasis alopecia areata treated with microneedling. doi:10.1080/08998280.2020.1753456 PubMed
[28] Marina Barletta et al.. Skin Appendage Disord. 2020. Successful Treatment of Alopecia Areata Patches with Triamcinolone Acetonide Using MMP®: Report of 2 Cases. doi:10.1159/000506314 PubMed
[29] Robert J Dabek et al.. Cureus. 2019. Fractional Laser-assisted Hair Regrowth and Microneedling for the Treatment of Alopecia Areata: A Review. doi:10.7759/cureus.4943 PubMed
[30] Angela Wipf et al.. J Cosmet Laser Ther. 2019. The rise of transcutaneous drug delivery for the management of alopecia: a review of existing literature and an eye towards … doi:10.1080/14764172.2018.1525743 PubMed
[31] R M Fertig et al.. J Eur Acad Dermatol Venereol. 2018. Microneedling for the treatment of hair loss? doi:10.1111/jdv.14722 PubMed
[32] Lauren C Strazzulla et al.. J Investig Dermatol Symp Proc. 2018. An Overview of the Biology of Platelet-Rich Plasma and Microneedling as Potential Treatments for Alopecia Areata. doi:10.1016/j.jisp.2017.10.002 PubMed
[33] Lauren C Strazzulla et al.. J Invest Dermatol. 2017. WITHDRAWN: An Overview of the Biology of Platelet-Rich Plasma and Microneedling as Potential Treatments for Alopecia Areata. doi:10.1016/j.jid.2017.07.827 PubMed
[34] Bs Chandrashekar et al.. J Cutan Aesthet Surg. 2014. Alopecia areata-successful outcome with microneedling and triamcinolone acetonide. doi:10.4103/0974-2077.129989 PubMed

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