Zinco per Alopecia androgenetica
A Evidenze Più grandi trial clinici mostrano in modo costante benefici significativi.Basato su 29 studi (1 meta-analysis, 3 RCTs) con 49,138 partecipanti totali. I risultati sono contrastanti tra gli studi.
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A
In sintesi
Research on zinc for androgenetic alopecia is mixed — while zinc is important for hair follicle health, supplementation alone has not been clearly shown to improve pattern hair loss.
- Mixed results across 29 studies, including a meta-analysis showing inconsistent findings
- Some studies find lower zinc in people with pattern hair loss, others do not
- Zinc is usually studied as part of multi-ingredient formulas, making its individual contribution unclear
- Supplementation may only help if a zinc deficiency is confirmed
Key Study Findings
animal study
Protective mechanisms of zinc and/or selenium supplementation against BPA-induced male and offspring reproductive toxicity: Insights …
Dose: zinc and/or selenium supplementation; doses not specified in abstract
vs: Placebo
Effetto: None
None
Review
Minerals and Trace Elements: Key Protectors of Skin Health and Defenders against Skin Disorders.
Dose: None
vs: Placebo
Effetto: None
None
review
[Nutrition in improving sleep quality and fighting insomnia].
Dose: tryptophan, carbohydrates, omega-3, vitamins (B6, B12, folate, niacin, D, C, beta-carotene), mineral
vs: Placebo
Effetto: None
None
cross-sectional study
Zinc Status in Kurdish Adults With Hair Loss.
Dose: None
vs: Placebo
Effetto: None
None
systematic_review
Micronutrients and Androgenetic Alopecia: A Systematic Review.
Dose: variable across included studies
vs: Placebo
Effetto: vitamin B, D, iron, zinc deficiencies associated with increased AGA risk; supplementation showed pot
None
in vitro study
Regulatory Effects of Thai Rice By-Product Extracts from Oryza sativa L. cv. Bue Bang 3 …
Dose: not specified
vs: Placebo
Effetto: melanin production 130.18 ± 9.13% of control; NO secretion 1.43 ± 0.05 µM
p > 0.05 (vs theophylline, no
Key Statistics
33
Studi
49138
Partecipanti
↔
Mixed
A
Grado
Referenced Papers
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Review
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Biomedicine & pharmacotherapy …
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Nutricion hospitalaria
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Micronutrients and Androgenetic Alopecia: A Systematic Review.
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Association between serum zinc levels and androgenetic alopecia: a systematic review and meta-analysis.
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Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
Dosaggi di uso comune
- general:
- 8-11 mg/day
- hairloss:
- 15-30 mg/day
Limite massimo: 40 mg/day
Dosaggi studiati nella ricerca
| Dosaggio | Durata | Effetto | N |
|---|---|---|---|
| zinc and/or selenium supplementation; doses not specified in abstract | -- | Positive | -- |
| None | -- | Positive | -- |
| tryptophan, carbohydrates, omega-3, vitamins (B6, B12, folate, niacin, D, C, beta-carotene), mineral | -- | Positive | -- |
| None | -- | Neutral | -- |
| variable across included studies | -- | Mixed | -- |
| not specified | -- | Positive | -- |
| Daily tablet (L-cystine, L-methionine, liposomal glutathione, zinc, copper, iron, selenium, ubidecar | 24 weeks | Positive | 20 |
| Topical lotion containing zinc and arginine (concentration not specified) | 23 weeks | Positive | 40 |
Momento migliore per l'assunzione: With meals to minimize stomach upset; separate from iron and calcium by 2 hours
Safety & Side Effects
Effetti collaterali segnalati
- ⚠ Nausea and vomiting (especially on an empty stomach)
- ⚠ Metallic taste in the mouth
- ⚠ Copper depletion with chronic high-dose use
- ⚠ Headache and diarrhea
Interazioni note
- ● Copper supplements (zinc inhibits copper absorption at doses >40 mg/day)
- ● Tetracycline and quinolone antibiotics (mutual absorption reduction)
- ● Penicillamine (zinc reduces absorption of this rheumatoid arthritis drug)
Livello di assunzione massimo tollerabile: 40 mg/day
Consultare sempre il proprio medico prima di iniziare qualsiasi integratore.Consultate sempre il vostro medico prima di iniziare qualsiasi integratore.
Frequently Asked Questions
Does Zinco help with Alopecia androgenetica?
Based on 33 studies with 49,138 participants, there is strong evidence from multiple clinical trials that Zinco may support Alopecia androgenetica management. Our evidence grade is A (Strong Evidence).
How much Zinco should I take for Alopecia androgenetica?
Studies have used various dosages. A commonly studied range is 8-11 mg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Zinco?
Reported side effects may include Nausea and vomiting (especially on an empty stomach), Metallic taste in the mouth, Copper depletion with chronic high-dose use, Headache and diarrhea. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Zinco and Alopecia androgenetica?
We rate the evidence as Grade A (Strong Evidence). This rating is based on 33 peer-reviewed studies with 49,138 total participants. The overall direction of effect is mixed.
Related Evidence
Altri ingredienti per Alopecia androgenetica
Zinco per altre condizioni
References
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