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Фолат для Телогеновый эффлувиум

B

На основе 6 исследований с участием 4,166 участников. Результаты исследований неоднозначны.

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B

Итог

There is limited evidence connecting folate to telogen effluvium — while low folate levels have been observed in some patients, research does not yet support folate supplementation as a reliable approach for this condition.

  • Mixed results across 6 studies — no consistent pattern linking folate levels to telogen effluvium
  • All studies are observational; no randomized controlled trials exist for this specific use
  • Folate is one of many micronutrients that may play a supporting role in hair health
  • A comprehensive nutritional assessment may be more useful than supplementing folate alone

Key Study Findings

Retrospective cohort n=2851
Retrospective Review of 2851 Female Patients With Telogen Effluvium: A Single-Center Experience.
Dose: None или: Placebo Эффект: Ferritin low in 46.5% of patients; iron deficiency in 29.5% p<0.05
Cross-Sectional Study n=108
Evaluation of the relationship of digital phototrichogram findings of patients with diffuse hair loss with …
Dose: None или: Placebo Эффект: None 0.05
Case-control n=973
Micronutrient Deficiencies and Digital Computerized Phototrichogram Analysis in Telogen Effluvium: a Retrospective Correlation Study in …
Dose: None или: Placebo Эффект: r=0.417 (HGB and AHR in females) p=0.008
retrospective cohort study n=3028
Telogen effluvium in daily practice: Patient characteristics, laboratory parameters, and treatment modalities of 3028 patients …
Dose: standard replacement doses или: Placebo Эффект: vitamin D deficient: 72.2%; B12 deficient: 30.7%; iron deficiency anemia: 6.2% None
randomized controlled trial 26 weeks
Comparative evaluation between two nutritional supplements in the improvement of telogen effluvium.
Dose: recommended daily intake amounts; taken orally for 180 days или: Placebo Эффект: Group 1 trichoscopy improvement 11.09% vs Group 2 7.76% after 180 days (significant for Group 1 only P<0.05 for clinical parameters

Key Statistics

10

Исследования

7126

Участники

Mixed

B

Оценка

Referenced Papers

Acta dermatovenerologica Croatica … 2016 6 цитирований
Dermatologic clinics 1993 38 цитирований

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Часто используемые дозировки

general:
400 mcg DFE/day

Верхний предел: 1,000 mcg/day (synthetic folic acid)

Дозировки, изученные в исследованиях

Дозировка Длительность Эффект N
None -- Neutral 2851
None -- Mixed --
None -- Mixed 108
None -- Positive 973
standard replacement doses -- Neutral 3028
recommended daily intake amounts; taken orally for 180 days 26 weeks Positive --
psychiatric and dermatological management -- Neutral 1
None -- Negative --

Лучшее время приёма: With meals for better absorption

Safety & Side Effects

Зарегистрированные побочные эффекты

  • Generally well tolerated
  • May mask vitamin B12 deficiency symptoms at high doses
  • Rare: abdominal cramps, insomnia

Известные взаимодействия

  • Methotrexate (folate antagonist; consult physician)
  • Anticonvulsants (phenytoin, carbamazepine) may reduce folate levels
  • Sulfasalazine (reduces folate absorption)

Допустимый верхний уровень потребления: 1,000 mcg/day (synthetic folic acid)

Всегда консультируйтесь с врачом перед началом приёма любых добавок.Всегда консультируйтесь с лечащим врачом перед началом приёма любой добавки.

Frequently Asked Questions

Does Фолат help with Телогеновый эффлувиум?
Based on 10 studies with 7,126 participants, there is moderate evidence from clinical studies that Фолат may support Телогеновый эффлувиум management. Our evidence grade is B (Good Evidence).
How much Фолат should I take for Телогеновый эффлувиум?
Studies have used various dosages. A commonly studied range is 400 mcg DFE/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Фолат?
Reported side effects may include Generally well tolerated, May mask vitamin B12 deficiency symptoms at high doses, Rare: abdominal cramps, insomnia. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Фолат and Телогеновый эффлувиум?
We rate the evidence as Grade B (Good Evidence). This rating is based on 10 peer-reviewed studies with 7,126 total participants. The overall direction of effect is mixed.

Related Evidence

Отказ от ответственности FDA: Данные утверждения не были оценены Управлением по санитарному надзору за качеством пищевых продуктов и медикаментов (FDA). Продукты и информация на этом сайте не предназначены для диагностики, лечения, излечения или профилактики каких-либо заболеваний. Представленные оценки доказательности основаны на нашем анализе опубликованных рецензируемых исследований и не являются медицинской консультацией. Всегда консультируйтесь с лечащим врачом перед началом приёма любых добавок.