パンプキンシードオイル：男性型・女性型脱毛症（AGA）

Q: Does パンプキンシードオイル help with 男性型・女性型脱毛症（AGA）?

Based on 15 studies with 1,874 participants, there is strong evidence from multiple clinical trials that パンプキンシードオイル may support 男性型・女性型脱毛症（AGA） management. Our evidence grade is A (Strong Evidence).

Q: How much パンプキンシードオイル should I take for 男性型・女性型脱毛症（AGA）?

Studies have used various dosages. A commonly studied range is 400 mg/day. Always consult your healthcare provider before starting any supplement regimen.

Q: Are there side effects of パンプキンシードオイル?

Reported side effects may include Mild gastrointestinal upset, Possible stomach discomfort at high doses, Rare allergic reactions in individuals with cucurbit allergies. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

Q: How strong is the evidence for パンプキンシードオイル and 男性型・女性型脱毛症（AGA）?

We rate the evidence as Grade A (Strong Evidence). This rating is based on 15 peer-reviewed studies with 1,874 total participants. The overall direction of effect is positive.

A エビデンス複数の大規模臨床試験が一貫して有意な効果を示しています。

合計1,874名の参加者を対象とした14件の研究（メタアナリシス2件、RCT 3件を含む）に基づく。14件中13件の研究で肯定的な効果が示されている。

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結論

Pumpkin seed oil is well-supported by multiple clinical trials as a natural supplement that may help promote hair growth in androgenetic alopecia through its DHT-blocking properties.

13 out of 14 studies show positive effects, including 3 RCTs
Acts as a natural 5-alpha reductase inhibitor, potentially reducing DHT levels
Both oral supplementation and topical application have been studied
One RCT showed comparable results to minoxidil 5% in women

Key Study Findings

narrative review

Addressing the Root Causes of Female Hair Loss and Non-Pharmaceutical Interventions.

Dose: None vs: Placebo 効果: None None

RCT n=80 24 weeks Double-blind

Oral Supplementation with l-Cystine, Serenoa repens, Cucurbita pepo, and Pygeum africanum in Chronic Telogen Effluvium …

Dose: 1 capsule daily (l-Cystine, Serenoa repens, Cucurbita pepo, Pygeum africanum, vitamins, micronutrien vs: Placebo 効果: MD=+12.3 hairs/cm2 at 6 months p<0.05

narrative review

Herbal Remedies for Hair Loss: A Review of Efficacy and Safety.

Dose: varies by remedy and study vs: Placebo 効果: None None

systematic review n=1658 Double-blind

Effects of dietary supplements on androgenetic alopecia: a systematic review and network meta-analysis.

Dose: various dietary supplements (Nutrafol, apple extract, tocotrienols, pumpkin seed oil, Cistanche/Lami vs: Placebo 効果: None None

review Single-blind

Do Non-Prescription Products Help in Managing Androgenic Alopecia?

Dose: Various non-prescription agents: procyanidin, cetirizine, caffeine, Oryza sativa bran, pumpkin seed vs: Placebo 効果: Considerable improvements in one or more parameters across 13 included studies None

review

Emerging and traditional 5-α reductase inhibitors and androgen receptor antagonists for male androgenetic alopecia.

Dose: finasteride 1 mg/day; dutasteride 0.5 mg/day; various natural product doses vs: Placebo 効果: None None

Key Statistics

研究数

1874

参加者数

↑

Positive

グレード

Referenced Papers

Herbal Remedies for Hair Loss: A Review of Efficacy and Safety. Review

Skin appendage disorders 2025 7 件の引用

Oral Supplementation with l-Cystine, Serenoa repens, Cucurbita pepo, and Pygeum africanum in Chronic Telogen Effluvium and Androgenetic Alopecia: A Double-Blind, … Other

Skin appendage disorders 2025 3 件の引用

Impact of a Novel Dietary Supplement on Efficacy of Pharmacological Treatments for Androgenic Alopecia: A Real-Life, Multicenter, Randomized, Assessor-Blinded Trial … RCT

Journal of cosmetic … 2025 1 件の引用

Do Non-Prescription Products Help in Managing Androgenic Alopecia? Review

Skin appendage disorders 2025 1 件の引用

Effects of dietary supplements on androgenetic alopecia: a systematic review and network meta-analysis. Systematic Review

Frontiers in nutrition 2025

Addressing the Root Causes of Female Hair Loss and Non-Pharmaceutical Interventions. Review

Journal of drugs … 2025

Complementary and alternative supplements: a review of dermatologic effectiveness for androgenetic alopecia. Review

Proceedings (Baylor University. … 2024 14 件の引用

Emerging and traditional 5-α reductase inhibitors and androgen receptor antagonists for male androgenetic alopecia. Review

Expert opinion on … 2024 8 件の引用

An Overview of Commonly Used Natural Alternatives for the Treatment of Androgenetic Alopecia, with Special Emphasis on Rosemary Oil. Review

Clinical, cosmetic and … 2024 7 件の引用

Natural products for male androgenetic alopecia. Review

Dermatologic therapy 2022 41 件の引用

Pumpkin seed oil vs. minoxidil 5% topical foam for the treatment of female pattern hair loss: A randomized comparative trial. RCT

Journal of cosmetic … 2021 29 件の引用

Herbal preparations for the treatment of hair loss. Review

Archives of dermatological … 2020 51 件の引用

The Use of Natural Ingredients in the Treatment of Alopecias with an Emphasis on Central Centrifugal Cicatricial Alopecia: A Systematic … Review

The Journal of … 2020 24 件の引用

An overview of herbal alternatives in androgenetic alopecia. Review

Journal of cosmetic … 2019 100 件の引用

Beneficial effects of pumpkin seed oil as a topical hair growth promoting agent in a mice model. Other

Avicenna journal of … 2019 23 件の引用

Comment on "effect of pumpkin seed oil on hair growth in men with androgenetic alopecia: a randomized, double-blind, placebo-controlled trial". Other

Evidence-based complementary and … 2015 4 件の引用

Effect of pumpkin seed oil on hair growth in men with androgenetic alopecia: a randomized, double-blind, placebo-controlled trial. Other

Evidence-based complementary and … 2014 86 件の引用

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

一般的な使用量

hairloss:: 400 mg/day

上限量： Not established

研究で検討された用量

用量	期間	効果	N
None	--	Positive	--
1 capsule daily (l-Cystine, Serenoa repens, Cucurbita pepo, Pygeum africanum, vitamins, micronutrien	24 weeks	Positive	80
varies by remedy and study	--	Positive	--
various dietary supplements (Nutrafol, apple extract, tocotrienols, pumpkin seed oil, Cistanche/Lami	--	Positive	1658
Various non-prescription agents: procyanidin, cetirizine, caffeine, Oryza sativa bran, pumpkin seed	--	Positive	--
finasteride 1 mg/day; dutasteride 0.5 mg/day; various natural product doses	--	Positive	--
various CAMs: pumpkin seed oil, saw palmetto, melatonin extract, caffeine extract, rosemary oil	--	Positive	--
not specified	--	Positive	--

推奨摂取タイミング： With meals for better absorption

Safety & Side Effects

報告されている副作用

⚠ Mild gastrointestinal upset
⚠ Possible stomach discomfort at high doses
⚠ Rare allergic reactions in individuals with cucurbit allergies

既知の相互作用

● Anticoagulants (theoretical increased bleeding risk)
● Lithium (pumpkin seed oil may have diuretic properties)

耐容上限摂取量： Not established

サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。

Frequently Asked Questions

Does パンプキンシードオイル help with 男性型・女性型脱毛症（AGA）?

Based on 15 studies with 1,874 participants, there is strong evidence from multiple clinical trials that パンプキンシードオイル may support 男性型・女性型脱毛症（AGA） management. Our evidence grade is A (Strong Evidence).

How much パンプキンシードオイル should I take for 男性型・女性型脱毛症（AGA）?

Studies have used various dosages. A commonly studied range is 400 mg/day. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of パンプキンシードオイル?

Reported side effects may include Mild gastrointestinal upset, Possible stomach discomfort at high doses, Rare allergic reactions in individuals with cucurbit allergies. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for パンプキンシードオイル and 男性型・女性型脱毛症（AGA）?

We rate the evidence as Grade A (Strong Evidence). This rating is based on 15 peer-reviewed studies with 1,874 total participants. The overall direction of effect is positive.

に関する他の成分：男性型・女性型脱毛症（AGA）

ミノキシジル A フィナステリド A PRP療法 A デュタステリド A オメガ3脂肪酸 A マイクロニードリング A

総合評価

合計1,874名の参加者を対象とした14件の研究（メタアナリシス2件、RCT 3件を含む）に基づく。14件中13件の研究で肯定的な効果が示されている。

Evidence Strength92%

High confidence

研究の内訳

RCT (2)Meta (0)Other (13)

代替成分との比較

この症状に対する他の成分との比較をご覧ください。

に関するすべての成分を見る：男性型・女性型脱毛症（AGA）

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References

[1] Azhar Ahmed et al.. Skin Appendage Disord. 2025. Herbal Remedies for Hair Loss: A Review of Efficacy and Safety. doi:10.1159/000542876 PubMed
[2] Jaime Piquero-Casals et al.. Skin Appendage Disord. 2025. Oral Supplementation with l-Cystine, Serenoa repens, Cucurbita pepo, and Pygeum africanum in Chronic Telogen Effluvium and Androgenetic Alopecia: A Double-Blind, … doi:10.1159/000540081 PubMed
[3] Massimo Milani et al.. J Cosmet Dermatol. 2025. Impact of a Novel Dietary Supplement on Efficacy of Pharmacological Treatments for Androgenic Alopecia: A Real-Life, Multicenter, Randomized, Assessor-Blinded Trial … doi:10.1111/jocd.70388 PubMed
[4] Aditya K Gupta et al.. Skin Appendage Disord. 2025. Do Non-Prescription Products Help in Managing Androgenic Alopecia? doi:10.1159/000542880 PubMed
[5] Lei Zhou et al.. Front Nutr. 2025. Effects of dietary supplements on androgenetic alopecia: a systematic review and network meta-analysis. doi:10.3389/fnut.2025.1719711 PubMed
[6] Adam Leavitt et al.. J Drugs Dermatol. 2025. Addressing the Root Causes of Female Hair Loss and Non-Pharmaceutical Interventions. doi:10.36849/JDD.8763 PubMed
[7] Promise Ufomadu. Proc (Bayl Univ Med Cent). 2024. Complementary and alternative supplements: a review of dermatologic effectiveness for androgenetic alopecia. doi:10.1080/08998280.2023.2263829 PubMed
[8] Aditya K Gupta et al.. Expert Opin Emerg Drugs. 2024. Emerging and traditional 5-α reductase inhibitors and androgen receptor antagonists for male androgenetic alopecia. doi:10.1080/14728214.2024.2346590 PubMed
[9] Nouf F Bin Rubaian et al.. Clin Cosmet Investig Dermatol. 2024. An Overview of Commonly Used Natural Alternatives for the Treatment of Androgenetic Alopecia, with Special Emphasis on Rosemary Oil. doi:10.2147/CCID.S470989 PubMed
[10] Aditya K Gupta et al.. Dermatol Ther. 2022. Natural products for male androgenetic alopecia. doi:10.1111/dth.15323 PubMed
[11] Ibrahim M Ibrahim et al.. J Cosmet Dermatol. 2021. Pumpkin seed oil vs. minoxidil 5% topical foam for the treatment of female pattern hair loss: A randomized comparative trial. doi:10.1111/jocd.13976 PubMed
[12] Ana Zgonc Škulj et al.. Arch Dermatol Res. 2020. Herbal preparations for the treatment of hair loss. doi:10.1007/s00403-019-02003-x PubMed
[13] Nneamaka Ezekwe et al.. J Clin Aesthet Dermatol. 2020. The Use of Natural Ingredients in the Treatment of Alopecias with an Emphasis on Central Centrifugal Cicatricial Alopecia: A Systematic … PubMed
[14] Maria Yusuf Dhariwala et al.. J Cosmet Dermatol. 2019. An overview of herbal alternatives in androgenetic alopecia. doi:10.1111/jocd.12930 PubMed
[15] Valiollah Hajhashemi et al.. Avicenna J Phytomed. 2019. Beneficial effects of pumpkin seed oil as a topical hair growth promoting agent in a mice model. doi:10.22038/AJP.2019.13463 PubMed
[16] Hitesh Verma. Evid Based Complement Alternat Med. 2015. Comment on "effect of pumpkin seed oil on hair growth in men with androgenetic alopecia: a randomized, double-blind, placebo-controlled trial". doi:10.1155/2015/271474 PubMed
[17] Young Hye Cho et al.. Evid Based Complement Alternat Med. 2014. Effect of pumpkin seed oil on hair growth in men with androgenetic alopecia: a randomized, double-blind, placebo-controlled trial. doi:10.1155/2014/549721 PubMed

FDAに関する免責事項: これらの記述は米国食品医薬品局（FDA）による評価を受けていません。本ウェブサイトの製品および情報は、疾病の診断、治療、治癒、または予防を目的としたものではありません。表示されているエビデンスグレードは、公開された査読済み研究の分析に基づいており、医療上の助言を構成するものではありません。サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。

パンプキンシードオイル ： 男性型・女性型脱毛症（AGA）