南瓜籽油 用于 雄激素性脱发
A基于14项研究（2项荟萃分析、3项RCT），共1,874名参与者。13/14项研究显示积极效果。
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A
结论
Pumpkin seed oil is well-supported by multiple clinical trials as a natural supplement that may help promote hair growth in androgenetic alopecia through its DHT-blocking properties.
- 13 out of 14 studies show positive effects, including 3 RCTs
- Acts as a natural 5-alpha reductase inhibitor, potentially reducing DHT levels
- Both oral supplementation and topical application have been studied
- One RCT showed comparable results to minoxidil 5% in women
Key Study Findings
narrative review
Addressing the Root Causes of Female Hair Loss and Non-Pharmaceutical Interventions.
Dose: None
vs: Placebo
效果: None
None
RCT
n=80
24 weeks
Double-blind
Oral Supplementation with l-Cystine, Serenoa repens, Cucurbita pepo, and Pygeum africanum in Chronic Telogen Effluvium …
Dose: 1 capsule daily (l-Cystine, Serenoa repens, Cucurbita pepo, Pygeum africanum, vitamins, micronutrien
vs: Placebo
效果: MD=+12.3 hairs/cm2 at 6 months
p<0.05
narrative review
Herbal Remedies for Hair Loss: A Review of Efficacy and Safety.
Dose: varies by remedy and study
vs: Placebo
效果: None
None
systematic review
n=1658
Double-blind
Effects of dietary supplements on androgenetic alopecia: a systematic review and network meta-analysis.
Dose: various dietary supplements (Nutrafol, apple extract, tocotrienols, pumpkin seed oil, Cistanche/Lami
vs: Placebo
效果: None
None
review
Single-blind
Do Non-Prescription Products Help in Managing Androgenic Alopecia?
Dose: Various non-prescription agents: procyanidin, cetirizine, caffeine, Oryza sativa bran, pumpkin seed
vs: Placebo
效果: Considerable improvements in one or more parameters across 13 included studies
None
review
Emerging and traditional 5-α reductase inhibitors and androgen receptor antagonists for male androgenetic alopecia.
Dose: finasteride 1 mg/day; dutasteride 0.5 mg/day; various natural product doses
vs: Placebo
效果: None
None
Key Statistics
15
研究数量
1874
受试者
↑
Positive
A
等级
Referenced Papers
Skin appendage disorders
2025
7 次引用
Skin appendage disorders
2025
3 次引用
Journal of cosmetic …
2025
1 次引用
Skin appendage disorders
2025
1 次引用
Effects of dietary supplements on androgenetic alopecia: a systematic review and network meta-analysis.
Systematic Review
Frontiers in nutrition
2025
Journal of drugs …
2025
Proceedings (Baylor University. …
2024
14 次引用
Expert opinion on …
2024
8 次引用
Clinical, cosmetic and …
2024
7 次引用
Dermatologic therapy
2022
41 次引用
Journal of cosmetic …
2021
29 次引用
Archives of dermatological …
2020
51 次引用
The Journal of …
2020
24 次引用
Journal of cosmetic …
2019
100 次引用
Beneficial effects of pumpkin seed oil as a topical hair growth promoting agent in a mice model.
Other
Avicenna journal of …
2019
23 次引用
Evidence-based complementary and …
2015
4 次引用
Evidence-based complementary and …
2014
86 次引用
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
常用剂量
- hairloss:
- 400 mg/day
上限： Not established
研究中使用的剂量
| 剂量 | 持续时间 | 效果 | N |
|---|---|---|---|
| None | -- | Positive | -- |
| 1 capsule daily (l-Cystine, Serenoa repens, Cucurbita pepo, Pygeum africanum, vitamins, micronutrien | 24 weeks | Positive | 80 |
| varies by remedy and study | -- | Positive | -- |
| various dietary supplements (Nutrafol, apple extract, tocotrienols, pumpkin seed oil, Cistanche/Lami | -- | Positive | 1658 |
| Various non-prescription agents: procyanidin, cetirizine, caffeine, Oryza sativa bran, pumpkin seed | -- | Positive | -- |
| finasteride 1 mg/day; dutasteride 0.5 mg/day; various natural product doses | -- | Positive | -- |
| various CAMs: pumpkin seed oil, saw palmetto, melatonin extract, caffeine extract, rosemary oil | -- | Positive | -- |
| not specified | -- | Positive | -- |
最佳服用时间： With meals for better absorption
Safety & Side Effects
已报告的副作用
- ⚠ Mild gastrointestinal upset
- ⚠ Possible stomach discomfort at high doses
- ⚠ Rare allergic reactions in individuals with cucurbit allergies
已知相互作用
- ● Anticoagulants (theoretical increased bleeding risk)
- ● Lithium (pumpkin seed oil may have diuretic properties)
可耐受最高摄入量： Not established
在开始服用任何补充剂之前，请务必咨询您的医疗保健提供者。
Frequently Asked Questions
Does 南瓜籽油 help with 雄激素性脱发?
Based on 15 studies with 1,874 participants, there is strong evidence from multiple clinical trials that 南瓜籽油 may support 雄激素性脱发 management. Our evidence grade is A (Strong Evidence).
How much 南瓜籽油 should I take for 雄激素性脱发?
Studies have used various dosages. A commonly studied range is 400 mg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of 南瓜籽油?
Reported side effects may include Mild gastrointestinal upset, Possible stomach discomfort at high doses, Rare allergic reactions in individuals with cucurbit allergies. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for 南瓜籽油 and 雄激素性脱发?
We rate the evidence as Grade A (Strong Evidence). This rating is based on 15 peer-reviewed studies with 1,874 total participants. The overall direction of effect is positive.
Related Evidence
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