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Folat untuk Telogen Effluvium

B

Berdasarkan 6 studi dengan 4,166 peserta secara total. Hasil bervariasi di antara studi-studi tersebut.

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B

Kesimpulan

There is limited evidence connecting folate to telogen effluvium — while low folate levels have been observed in some patients, research does not yet support folate supplementation as a reliable approach for this condition.

  • Mixed results across 6 studies — no consistent pattern linking folate levels to telogen effluvium
  • All studies are observational; no randomized controlled trials exist for this specific use
  • Folate is one of many micronutrients that may play a supporting role in hair health
  • A comprehensive nutritional assessment may be more useful than supplementing folate alone

Key Study Findings

Retrospective cohort n=2851
Retrospective Review of 2851 Female Patients With Telogen Effluvium: A Single-Center Experience.
Dose: None vs: Placebo Efek: Ferritin low in 46.5% of patients; iron deficiency in 29.5% p<0.05
retrospective cohort study n=3028
Telogen effluvium in daily practice: Patient characteristics, laboratory parameters, and treatment modalities of 3028 patients …
Dose: standard replacement doses vs: Placebo Efek: vitamin D deficient: 72.2%; B12 deficient: 30.7%; iron deficiency anemia: 6.2% None
randomized controlled trial 26 weeks
Comparative evaluation between two nutritional supplements in the improvement of telogen effluvium.
Dose: recommended daily intake amounts; taken orally for 180 days vs: Placebo Efek: Group 1 trichoscopy improvement 11.09% vs Group 2 7.76% after 180 days (significant for Group 1 only P<0.05 for clinical parameters

Key Statistics

10

Studi

7126

Peserta

Mixed

B

Peringkat

Referenced Papers

Acta dermatovenerologica Croatica … 2016 6 sitasi
Dermatologic clinics 1993 38 sitasi

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Dosis yang Umum Digunakan

general:
400 mcg DFE/day

Batas atas: 1,000 mcg/day (synthetic folic acid)

Dosis yang Diteliti dalam Penelitian

Dosis Durasi Efek N
None -- Neutral 2851
None -- Mixed --
None -- Mixed 108
None -- Positive 973
standard replacement doses -- Neutral 3028
recommended daily intake amounts; taken orally for 180 days 26 weeks Positive --
psychiatric and dermatological management -- Neutral 1
None -- Negative --

Waktu terbaik diminum: With meals for better absorption

Safety & Side Effects

Efek Samping yang Dilaporkan

  • Generally well tolerated
  • May mask vitamin B12 deficiency symptoms at high doses
  • Rare: abdominal cramps, insomnia

Interaksi yang Diketahui

  • Methotrexate (folate antagonist; consult physician)
  • Anticonvulsants (phenytoin, carbamazepine) may reduce folate levels
  • Sulfasalazine (reduces folate absorption)

Asupan atas yang dapat ditoleransi: 1,000 mcg/day (synthetic folic acid)

Selalu konsultasikan dengan tenaga kesehatan Anda sebelum memulai suplemen apa pun.Selalu konsultasikan dengan penyedia layanan kesehatan Anda sebelum memulai suplemen apa pun.

Frequently Asked Questions

Does Folat help with Telogen Effluvium?
Based on 10 studies with 7,126 participants, there is moderate evidence from clinical studies that Folat may support Telogen Effluvium management. Our evidence grade is B (Good Evidence).
How much Folat should I take for Telogen Effluvium?
Studies have used various dosages. A commonly studied range is 400 mcg DFE/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Folat?
Reported side effects may include Generally well tolerated, May mask vitamin B12 deficiency symptoms at high doses, Rare: abdominal cramps, insomnia. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Folat and Telogen Effluvium?
We rate the evidence as Grade B (Good Evidence). This rating is based on 10 peer-reviewed studies with 7,126 total participants. The overall direction of effect is mixed.

Related Evidence

Penafian FDA: Pernyataan-pernyataan ini belum dievaluasi oleh Food and Drug Administration. Produk dan informasi di situs web ini tidak dimaksudkan untuk mendiagnosis, mengobati, menyembuhkan, atau mencegah penyakit apa pun. Peringkat bukti yang disajikan didasarkan pada analisis kami terhadap penelitian yang ditinjau sejawat dan tidak merupakan saran medis. Selalu konsultasikan dengan penyedia layanan kesehatan Anda sebelum memulai regimen suplemen apa pun.