Keratin untuk Telogen Effluvium
B Bukti Setidaknya satu uji coba acak mendukung hal ini, dengan hasil yang sebagian besar konsisten.Berdasarkan 5 studi (1 RCT) dengan 60 peserta secara total. Mayoritas studi tidak menunjukkan efek yang signifikan.
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B
Kesimpulan
Research does not support keratin supplementation as helpful for telogen effluvium — the limited evidence available suggests it is unlikely to meaningfully reduce this type of hair shedding.
- Majority of studies show negative or no effects for keratin in telogen effluvium
- Very small participant pool (60 people) limits the reliability of findings
- Telogen effluvium has different underlying mechanisms than age-related thinning, where keratin shows more promise
- Other approaches may be more effective for addressing telogen effluvium specifically
Key Study Findings
Case Reports
n=1
Open-label
Plica Neuropathica (Polonica) Secondary to Diffuse Alopecia: A Case Report and Literature Review.
Dose: None
vs: None
Outcome: None
Efek: None
None
Populasi: 62-year-old female with diffuse alopecia and plica neuropathica
Systematic Review
Regenerative medicine in the treatment of specific dermatologic disorders: a systematic review of randomized controlled …
Dose: Various regenerative methods
vs: Standard treatment or placebo
Outcome: Dermatologic disease improvement
Efek: None
None
Populasi: Patients with specific dermatologic diseases
Review
The Role of One-Carbon Metabolism in Healthy Brain Aging.
Dose: None
vs: None
Outcome: folate status
Efek: None
None
Populasi: None
Review
Regenerative medicine strategies for hair growth and regeneration: A narrative review of literature.
Dose: None
vs: None
Outcome: Hair regrowth
Efek: None
None
Populasi: Alopecia patients
Other
Reply to "Vitamin D status in scarring and nonscarring alopecia".
Dose: None
vs: None
Outcome: None
Efek: None
None
Populasi: None
Key Statistics
11
Studi
61
Peserta
↑
Positive
B
Peringkat
Referenced Papers
Plica Neuropathica (Polonica) Secondary to Diffuse Alopecia: A Case Report and Literature Review.
Case Report
Cureus
2025
Scientific reports
2025
Regenerative medicine in the treatment of specific dermatologic disorders: a systematic review of randomized controlled clinical trials.
Systematic Review
Stem cell research …
2024
2 sitasi
Nutrients
2023
9 sitasi
Regenerative medicine strategies for hair growth and regeneration: A narrative review of literature.
Review
Regenerative therapy
2022
96 sitasi
Journal of the …
2022
6 sitasi
Journal of cosmetic …
2021
44 sitasi
Experimental dermatology
2020
10 sitasi
Clinical, cosmetic and …
2019
7 sitasi
Comparative evaluation between two nutritional supplements in the improvement of telogen effluvium.
Other
Clinical, cosmetic and …
2018
16 sitasi
Medical archives (Sarajevo, …
2018
16 sitasi
Journal of photochemistry …
2018
16 sitasi
Experimental dermatology
2003
35 sitasi
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
Dosis yang Umum Digunakan
- hairloss:
- 500 mg/day
Batas atas: Not established
Dosis yang Diteliti dalam Penelitian
| Dosis | Durasi | Efek | N |
|---|---|---|---|
| None | -- | Mixed | 1 |
| Various regenerative methods | -- | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Mixed | -- |
| None | -- | Negative | -- |
| not applicable (genetic association study) | -- | Negative | 60 |
| recommended daily intake amounts; taken orally for 180 days | 26 weeks | Positive | -- |
Waktu terbaik diminum: With meals for better absorption
Safety & Side Effects
Efek Samping yang Dilaporkan
- ⚠ Generally well tolerated
- ⚠ Mild gastrointestinal discomfort in some individuals
- ⚠ Rare allergic reactions
Interaksi yang Diketahui
- ● No significant drug interactions established
- ● May interact with protein absorption in individuals with digestive disorders
Asupan atas yang dapat ditoleransi: Not established
Selalu konsultasikan dengan tenaga kesehatan Anda sebelum memulai suplemen apa pun.Selalu konsultasikan dengan penyedia layanan kesehatan Anda sebelum memulai suplemen apa pun.
Frequently Asked Questions
Does Keratin help with Telogen Effluvium?
Based on 11 studies with 61 participants, there is moderate evidence from clinical studies that Keratin may support Telogen Effluvium management. Our evidence grade is B (Good Evidence).
How much Keratin should I take for Telogen Effluvium?
Studies have used various dosages. A commonly studied range is 500 mg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Keratin?
Reported side effects may include Generally well tolerated, Mild gastrointestinal discomfort in some individuals, Rare allergic reactions. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Keratin and Telogen Effluvium?
We rate the evidence as Grade B (Good Evidence). This rating is based on 11 peer-reviewed studies with 61 total participants. The overall direction of effect is positive.
Related Evidence
Bahan lain untuk Telogen Effluvium
Keratin untuk kondisi lain
References
- [1] Alondra Saray Polanco-Llanes et al.. Cureus. 2025. Plica Neuropathica (Polonica) Secondary to Diffuse Alopecia: A Case Report and Literature Review. doi:10.7759/cureus.93402 PubMed
- [2] Stefanie Klingenstein et al.. Sci Rep. 2025. Ex vivo detection of SARS CoV 2 spike protein in human hair follicles and potential link to telogen effluvium. doi:10.1038/s41598-025-28909-3 PubMed
- [3] Alireza Jafarzadeh et al.. Stem Cell Res Ther. 2024. Regenerative medicine in the treatment of specific dermatologic disorders: a systematic review of randomized controlled clinical trials. doi:10.1186/s13287-024-03800-6 PubMed
- [4] Sapna Virdi et al.. Nutrients. 2023. The Role of One-Carbon Metabolism in Healthy Brain Aging. doi:10.3390/nu15183891 PubMed
- [5] Yusuke Shimizu et al.. Regen Ther. 2022. Regenerative medicine strategies for hair growth and regeneration: A narrative review of literature. doi:10.1016/j.reth.2022.10.005 PubMed
- [6] Shawn Afvari et al.. J Am Acad Dermatol. 2022. Reply to "Vitamin D status in scarring and nonscarring alopecia". doi:10.1016/j.jaad.2022.04.055 PubMed
- [7] Kriteeka Saini et al.. J Cosmet Dermatol. 2021. Role of vitamin D in hair loss: A short review. doi:10.1111/jocd.14421 PubMed
- [8] Ralf Paus et al.. Exp Dermatol. 2020. Topical L-thyroxine: The Cinderella among hormones waiting to dance on the floor of dermatological therapy? doi:10.1111/exd.14156 PubMed
- [9] Iman Seleit et al.. Clin Cosmet Investig Dermatol. 2019. Vitamin D Receptor Gene Polymorphism In Chronic Telogen Effluvium; A Case-Control Study. doi:10.2147/CCID.S227232 PubMed
- [10] Flávia Alvim Sant'Anna Addor et al.. Clin Cosmet Investig Dermatol. 2018. Comparative evaluation between two nutritional supplements in the improvement of telogen effluvium. doi:10.2147/CCID.S173082 PubMed
- [11] Erkin Pekmezci et al.. Med Arch. 2018. Proprietary Herbal Extract Downregulates the Gene Expression of IL-1α in HaCaT Cells: Possible Implications Against Nonscarring Alopecia. doi:10.5455/medarh.2018.72.136-140 PubMed
- [12] Thomas Hengl et al.. J Photochem Photobiol B. 2018. Cystine-thiamin-containing hair-growth formulation modulates the response to UV radiation in an in vitro model for growth-limiting conditions of human keratinocytes. doi:10.1016/j.jphotobiol.2018.09.005 PubMed
- [13] Petra Clara Arck et al.. Exp Dermatol. 2003. Topical minoxidil counteracts stress-induced hair growth inhibition in mice. doi:10.1034/j.1600-0625.2003.00028.x PubMed
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