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Kératine pour Telogen Effluvium

B Preuves Au moins un essai randomisé le soutient, avec des résultats globalement concordants.

Basé sur 5 études (1 RCT) avec 60 participants au total. La majorité des études ne montrent pas d’effets significatifs.

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B

En conclusion

Research does not support keratin supplementation as helpful for telogen effluvium — the limited evidence available suggests it is unlikely to meaningfully reduce this type of hair shedding.

  • Majority of studies show negative or no effects for keratin in telogen effluvium
  • Very small participant pool (60 people) limits the reliability of findings
  • Telogen effluvium has different underlying mechanisms than age-related thinning, where keratin shows more promise
  • Other approaches may be more effective for addressing telogen effluvium specifically

Key Study Findings

Case Reports n=1 Open-label
Plica Neuropathica (Polonica) Secondary to Diffuse Alopecia: A Case Report and Literature Review.
Dose: None vs: None Outcome: None Effet: None None

Population: 62-year-old female with diffuse alopecia and plica neuropathica

Systematic Review
Regenerative medicine in the treatment of specific dermatologic disorders: a systematic review of randomized controlled …
Dose: Various regenerative methods vs: Standard treatment or placebo Outcome: Dermatologic disease improvement Effet: None None

Population: Patients with specific dermatologic diseases

Review
The Role of One-Carbon Metabolism in Healthy Brain Aging.
Dose: None vs: None Outcome: folate status Effet: None None

Population: None

Review
Regenerative medicine strategies for hair growth and regeneration: A narrative review of literature.
Dose: None vs: None Outcome: Hair regrowth Effet: None None

Population: Alopecia patients

Other
Reply to "Vitamin D status in scarring and nonscarring alopecia".
Dose: None vs: None Outcome: None Effet: None None

Population: None

Review
Role of vitamin D in hair loss: A short review.
Dose: None vs: Placebo Effet: None None

Key Statistics

11

Études

61

Participants

Positive

B

Note

Referenced Papers

Journal of cosmetic … 2021 44 citations

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Posologies couramment utilisées

hairloss:
500 mg/day

Limite supérieure : Not established

Posologies étudiées dans la recherche

Posologie Durée Effet N
None -- Mixed 1
Various regenerative methods -- Positive --
None -- Positive --
None -- Positive --
None -- Mixed --
None -- Negative --
not applicable (genetic association study) -- Negative 60
recommended daily intake amounts; taken orally for 180 days 26 weeks Positive --

Moment optimal de prise : With meals for better absorption

Safety & Side Effects

Effets indésirables signalés

  • Generally well tolerated
  • Mild gastrointestinal discomfort in some individuals
  • Rare allergic reactions

Interactions connues

  • No significant drug interactions established
  • May interact with protein absorption in individuals with digestive disorders

Apport maximal tolérable : Not established

Consultez toujours votre professionnel de santé avant de commencer tout complément alimentaire.Consultez toujours votre professionnel de santé avant de commencer tout complément alimentaire.

Frequently Asked Questions

Does Kératine help with Telogen Effluvium?
Based on 11 studies with 61 participants, there is moderate evidence from clinical studies that Kératine may support Telogen Effluvium management. Our evidence grade is B (Good Evidence).
How much Kératine should I take for Telogen Effluvium?
Studies have used various dosages. A commonly studied range is 500 mg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Kératine?
Reported side effects may include Generally well tolerated, Mild gastrointestinal discomfort in some individuals, Rare allergic reactions. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Kératine and Telogen Effluvium?
We rate the evidence as Grade B (Good Evidence). This rating is based on 11 peer-reviewed studies with 61 total participants. The overall direction of effect is positive.

References

  1. [1] Alondra Saray Polanco-Llanes et al.. Cureus. 2025. Plica Neuropathica (Polonica) Secondary to Diffuse Alopecia: A Case Report and Literature Review. doi:10.7759/cureus.93402 PubMed
  2. [2] Stefanie Klingenstein et al.. Sci Rep. 2025. Ex vivo detection of SARS CoV 2 spike protein in human hair follicles and potential link to telogen effluvium. doi:10.1038/s41598-025-28909-3 PubMed
  3. [3] Alireza Jafarzadeh et al.. Stem Cell Res Ther. 2024. Regenerative medicine in the treatment of specific dermatologic disorders: a systematic review of randomized controlled clinical trials. doi:10.1186/s13287-024-03800-6 PubMed
  4. [4] Sapna Virdi et al.. Nutrients. 2023. The Role of One-Carbon Metabolism in Healthy Brain Aging. doi:10.3390/nu15183891 PubMed
  5. [5] Yusuke Shimizu et al.. Regen Ther. 2022. Regenerative medicine strategies for hair growth and regeneration: A narrative review of literature. doi:10.1016/j.reth.2022.10.005 PubMed
  6. [6] Shawn Afvari et al.. J Am Acad Dermatol. 2022. Reply to "Vitamin D status in scarring and nonscarring alopecia". doi:10.1016/j.jaad.2022.04.055 PubMed
  7. [7] Kriteeka Saini et al.. J Cosmet Dermatol. 2021. Role of vitamin D in hair loss: A short review. doi:10.1111/jocd.14421 PubMed
  8. [8] Ralf Paus et al.. Exp Dermatol. 2020. Topical L-thyroxine: The Cinderella among hormones waiting to dance on the floor of dermatological therapy? doi:10.1111/exd.14156 PubMed
  9. [9] Iman Seleit et al.. Clin Cosmet Investig Dermatol. 2019. Vitamin D Receptor Gene Polymorphism In Chronic Telogen Effluvium; A Case-Control Study. doi:10.2147/CCID.S227232 PubMed
  10. [10] Flávia Alvim Sant'Anna Addor et al.. Clin Cosmet Investig Dermatol. 2018. Comparative evaluation between two nutritional supplements in the improvement of telogen effluvium. doi:10.2147/CCID.S173082 PubMed
  11. [11] Erkin Pekmezci et al.. Med Arch. 2018. Proprietary Herbal Extract Downregulates the Gene Expression of IL-1α in HaCaT Cells: Possible Implications Against Nonscarring Alopecia. doi:10.5455/medarh.2018.72.136-140 PubMed
  12. [12] Thomas Hengl et al.. J Photochem Photobiol B. 2018. Cystine-thiamin-containing hair-growth formulation modulates the response to UV radiation in an in vitro model for growth-limiting conditions of human keratinocytes. doi:10.1016/j.jphotobiol.2018.09.005 PubMed
  13. [13] Petra Clara Arck et al.. Exp Dermatol. 2003. Topical minoxidil counteracts stress-induced hair growth inhibition in mice. doi:10.1034/j.1600-0625.2003.00028.x PubMed

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