Folat untuk Kerontokan Rambut Akibat Defisiensi Nutrisi

Berdasarkan 11 studi dengan 4,429 peserta secara total. Hasil bervariasi di antara studi-studi tersebut.

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Kesimpulan

The evidence linking folate supplementation to hair regrowth is limited and mixed — folate deficiency may contribute to hair loss in some cases, but supplementation is not well-supported as a general hair loss remedy.

Results are mixed across 11 studies, with no clear consensus on folate's role in hair loss
No randomized controlled trials have specifically tested folate supplementation for hair regrowth
Folate deficiency may be more relevant when caused by medications (e.g., methotrexate) rather than diet
Blood testing for folate levels may help determine if supplementation is appropriate

Key Study Findings

In Vitro

7-Hydroxycannabidiol and 7-carboxycannabidiol induced cytotoxicity via apoptosis and endoplasmic reticulum stress in human hepatic cells.

Dose: None vs: Untreated hepatic cells Outcome: Cytotoxicity via apoptosis and ER stress Efek: None None

Populasi: Primary human hepatocytes and HepG2 cells

Review

Safety First: A Comprehensive Review of Nutritional Supplements for Hair Loss in Breast Cancer Patients.

Dose: None vs: Placebo Efek: None None

Review

Medical Marijuana and Treatment Personalization: The Role of Genetics and Epigenetics in Response to THC …

Dose: None vs: None Outcome: None Efek: None None

Populasi: Review of pharmacogenomics of THC and CBD

In Vitro 2 weeks

Quality and safety of hemp meal as a protein supplement for nonlactating dairy cows.

Dose: 10.2% d vs: None Outcome: glycemic control Efek: None None

Populasi: Cows

Case-control n=973

Micronutrient Deficiencies and Digital Computerized Phototrichogram Analysis in Telogen Effluvium: a Retrospective Correlation Study in …

Dose: None vs: Placebo Efek: r=0.417 (HGB and AHR in females) p=0.008

retrospective cohort study n=3028

Telogen effluvium in daily practice: Patient characteristics, laboratory parameters, and treatment modalities of 3028 patients …

Dose: standard replacement doses vs: Placebo Efek: vitamin D deficient: 72.2%; B12 deficient: 30.7%; iron deficiency anemia: 6.2% None

Key Statistics

Studi

4166

Peserta

↔

Mixed

Peringkat

Referenced Papers

Safety First: A Comprehensive Review of Nutritional Supplements for Hair Loss in Breast Cancer Patients. Review

Nutrients 2025 2 sitasi

7-Hydroxycannabidiol and 7-carboxycannabidiol induced cytotoxicity via apoptosis and endoplasmic reticulum stress in human hepatic cells. Other

Archives of toxicology 2025 1 sitasi

Medical Marijuana and Treatment Personalization: The Role of Genetics and Epigenetics in Response to THC and CBD. Review

Genes 2025 1 sitasi

Quality and safety of hemp meal as a protein supplement for nonlactating dairy cows. Other

Journal of dairy … 2023 8 sitasi

Micronutrient Deficiencies and Digital Computerized Phototrichogram Analysis in Telogen Effluvium: a Retrospective Correlation Study in a Tertiary Medical Center. Other

Dermatology practical & … 2023 4 sitasi

Telogen effluvium in daily practice: Patient characteristics, laboratory parameters, and treatment modalities of 3028 patients with telogen effluvium. Other

Journal of cosmetic … 2022 22 sitasi

The Trouble with CBD Oil. Other

Medical cannabis and … 2018 158 sitasi

The Role of Micronutrients in Alopecia Areata: A Review. Review

American journal of … 2017 104 sitasi

Vitamin and Mineral Deficiencies in Patients With Telogen Effluvium: A Retrospective Cross-Sectional Study. Other

Journal of drugs … 2016 56 sitasi

The role of psychological factors and serum zinc, folate and vitamin B12 levels in the aetiology of trichodynia: a case-control … Other

Clinical and experimental … 2009 34 sitasi

Management of hair loss in women. Review

Dermatologic clinics 1993 38 sitasi

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Dosis yang Umum Digunakan

general:: 400 mcg DFE/day

Batas atas: 1,000 mcg/day (synthetic folic acid)

Dosis yang Diteliti dalam Penelitian

Dosis	Durasi	Efek	N
None	--	Negative	--
None	--	Mixed	--
None	--	Mixed	--
10.2% d	2 weeks	Mixed	--
None	--	Positive	973
standard replacement doses	--	Neutral	3028
None	--	Positive	--
None	--	Negative	--

Waktu terbaik diminum: With meals for better absorption

Safety & Side Effects

Efek Samping yang Dilaporkan

⚠ Generally well tolerated
⚠ May mask vitamin B12 deficiency symptoms at high doses
⚠ Rare: abdominal cramps, insomnia

Interaksi yang Diketahui

● Methotrexate (folate antagonist; consult physician)
● Anticonvulsants (phenytoin, carbamazepine) may reduce folate levels
● Sulfasalazine (reduces folate absorption)

Asupan atas yang dapat ditoleransi: 1,000 mcg/day (synthetic folic acid)

Selalu konsultasikan dengan tenaga kesehatan Anda sebelum memulai suplemen apa pun.Selalu konsultasikan dengan penyedia layanan kesehatan Anda sebelum memulai suplemen apa pun.

Frequently Asked Questions

Does Folat help with Kerontokan Rambut Akibat Defisiensi Nutrisi?

Based on 11 studies with 4,166 participants, there is insufficient evidence at this time that Folat may support Kerontokan Rambut Akibat Defisiensi Nutrisi management. Our evidence grade is F (Evidence Against).

How much Folat should I take for Kerontokan Rambut Akibat Defisiensi Nutrisi?

Studies have used various dosages. A commonly studied range is 400 mcg DFE/day. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Folat?

Reported side effects may include Generally well tolerated, May mask vitamin B12 deficiency symptoms at high doses, Rare: abdominal cramps, insomnia. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Folat and Kerontokan Rambut Akibat Defisiensi Nutrisi?

We rate the evidence as Grade F (Evidence Against). This rating is based on 11 peer-reviewed studies with 4,166 total participants. The overall direction of effect is mixed.

Related Evidence

Bahan lain untuk Kerontokan Rambut Akibat Defisiensi Nutrisi

Selenium A Biotin B Vitamin A D L-Cysteine D Vitamin B12 F

Folat untuk kondisi lain

Telogen Effluvium B

Kesimpulan Singkat

Berdasarkan 11 studi dengan 4,429 peserta secara total. Hasil bervariasi di antara studi-studi tersebut.

Evidence Strength10%

Low confidence

Rincian Studi

RCT (0)Meta (0)Other (11)

Bandingkan Alternatif

Lihat bagaimana bahan lain dibandingkan untuk kondisi ini.

Lihat semua bahan untuk Kerontokan Rambut Akibat Defisiensi Nutrisi

Pelajari Lebih Lanjut

Penafian FDA: Pernyataan-pernyataan ini belum dievaluasi oleh Food and Drug Administration. Produk dan informasi di situs web ini tidak dimaksudkan untuk mendiagnosis, mengobati, menyembuhkan, atau mencegah penyakit apa pun. Peringkat bukti yang disajikan didasarkan pada analisis kami terhadap penelitian yang ditinjau sejawat dan tidak merupakan saran medis. Selalu konsultasikan dengan penyedia layanan kesehatan Anda sebelum memulai regimen suplemen apa pun.