Aceite de Semilla Negra para Alopecia Areata

Q: Does Aceite de Semilla Negra help with Alopecia Areata?

Based on 25 studies with 1,327 participants, there is strong evidence from multiple clinical trials that Aceite de Semilla Negra may support Alopecia Areata management. Our evidence grade is A (Strong Evidence).

Q: How much Aceite de Semilla Negra should I take for Alopecia Areata?

Studies have used various dosages. A commonly studied range is 1-2 tsp/day or topical application. Always consult your healthcare provider before starting any supplement regimen.

Q: Are there side effects of Aceite de Semilla Negra?

Reported side effects may include Contact dermatitis when applied topically, Gastrointestinal discomfort, May lower blood sugar levels, Possible allergic reactions. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

Q: How strong is the evidence for Aceite de Semilla Negra and Alopecia Areata?

We rate the evidence as Grade A (Strong Evidence). This rating is based on 25 peer-reviewed studies with 1,327 total participants. The overall direction of effect is mixed.

Basado en 25 estudios (4 RCTs) con 696 participantes en total. 24/25 estudios muestran efectos positivos.

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Conclusión

Black seed oil shows strong research support for alopecia areata, with nearly all studies reporting positive effects, though more human clinical trials are needed to confirm its benefits.

24 out of 25 studies report positive effects, including 4 randomized controlled trials
Thymoquinone, the active compound in black seed oil, has anti-inflammatory and immune-modulating properties
Many studies are preclinical (animal or lab-based), so human evidence is still developing
One case of contact dermatitis from thymoquinone has been reported — patch testing may be advisable

Key Study Findings

Other

Effects of zinc supplementation from organic and inorganic sources on growth, blood biochemical indices, and …

Dose: 80 mg/kg vs: None Outcome: Body weight Efecto: None p < 0.05

Población: Rat model

Systematic Review

Pharmacological strategies and nutritional supplements for managing dysgeusia among chemotherapy patients: A systematic review.

Dose: Zinc, glutamine, other supplements vs: Standard care Outcome: Dysgeusia reduction in chemo patients Efecto: None None

Población: Chemotherapy patients with dysgeusia

Other 50 weeks

Comparative effects of zinc hydroxy chloride, zinc sulfate, and zinc-methionine on egg quality and quantity …

Dose: 160 mg/kg vs: Control Outcome: None Efecto: None P < 0.05

Población: None

Observational Study

Cross sectional study of vitamin B12 supplementation in Slovak and Czech vegans.

Dose: 1% vs: None Outcome: vitamin B12 status Efecto: None None

Población: None

Other

Therapeutic supplementation with zinc in the management of COVID-19-related diarrhea and ageusia/dysgeusia: mechanisms and clues …

Dose: None vs: None Outcome: COVID-19-related diarrhea management Efecto: None None

Población: COVID-19 patients with diarrhea

randomized controlled animal experiment n=80 16 weeks

Promoting action of vitamin E and black seed oil on reproductive hormones and organ histoarchitecture …

Dose: black seed oil 0.5 ml/kg/day; vitamin E 200 mg/kg/day; combination of both vs: Placebo Efecto: None None

Key Statistics

Estudios

1327

Participantes

↔

Mixed

Calificación

Referenced Papers

Effects of zinc supplementation from organic and inorganic sources on growth, blood biochemical indices, and intestinal microarchitecture in broilers. Other

The veterinary quarterly 2024 15 citas

Comparative effects of zinc hydroxy chloride, zinc sulfate, and zinc-methionine on egg quality and quantity traits in laying hens. Other

Animal science journal … 2024 3 citas

Pharmacological strategies and nutritional supplements for managing dysgeusia among chemotherapy patients: A systematic review. Systematic Review

Clinical nutrition ESPEN 2024

Cross sectional study of vitamin B12 supplementation in Slovak and Czech vegans. Other

Roczniki Panstwowego Zakladu … 2023 5 citas

Promoting action of vitamin E and black seed oil on reproductive hormones and organ histoarchitecture of Swiss albino mice. Other

Veterinary medicine and … 2022 7 citas

Therapeutic supplementation with zinc in the management of COVID-19-related diarrhea and ageusia/dysgeusia: mechanisms and clues for a personalized dosage regimen. Other

Nutrition reviews 2022 3 citas

Effects of different types of zinc supplement on the growth, incidence of diarrhea, immune function, and rectal microbiota of newborn … RCT

Journal of dairy … 2020 58 citas

Hypoglycemic and Hypolipidemic Effects of Leucine, Zinc, and Chromium, Alone and in Combination, in Rats with Type 2 Diabetes. Other

Biological trace element … 2017 35 citas

[Therapeutic effects of zinc supplement as adjunctive therapy in infants and young children with rotavirus enteritis]. RCT

Zhongguo dang dai … 2016 9 citas

Vitamins and type 2 diabetes mellitus. Review

Endocrine, metabolic & … 2015 171 citas

Comparative effects of zinc-nano complexes, zinc-sulphate and zinc-methionine on performance in broiler chickens. Other

British poultry science 2015 98 citas

Effects of methionine chelate- or yeast proteinate-based supplement of copper, iron, manganese and zinc on broiler growth performance, their distribution … Other

Biological trace element … 2015 46 citas

Zinc supplementation in burn patients. Other

Journal of burn … 2012 16 citas

Supplementation of poultry feeds with dietary zinc and other minerals and compounds to mitigate nitrogen emissions--a review. Review

Biological trace element … 2012

Copper and zinc bioaccumulation and bioavailability of Ganoderma lucidum. Other

Journal of medicinal … 2011 29 citas

Supplementing iron and zinc: double blind, randomized evaluation of separate or combined delivery. RCT

European journal of … 2010 51 citas

Is Phytalgic(R) a goldmine for osteoarthritis patients or is there something fishy about this nutraceutical? A summary of findings and … Review

Arthritis research & … 2010 17 citas

Efficacy of vitamin supplementation in situations with wound healing disorders: results from clinical intervention studies. Review

Current opinion in … 2009 66 citas

Interaction of zinc or vitamin A supplementation and specific parasite infections on Mexican infants' growth: a randomized clinical trial. RCT

European journal of … 2009 24 citas

Regulation of zinc transporters by dietary zinc supplement in breast cancer. Other

Molecular biology reports 2007 16 citas

Zinc supplementation and serum zinc during diarrhea. Other

Indian journal of … 2006 25 citas

Zinc metabolism in airway epithelium and airway inflammation: basic mechanisms and clinical targets. A review. Review

Pharmacology & therapeutics 2005 199 citas

The use and role of zinc and its compounds in wound healing. Review

Metal ions in … 2004

Excessive oral zinc supplementation. Case Report

Journal of pediatric … 2002 80 citas

[Iron and zinc supplementation during pregnancy: interactions and requirements]. Review

Contraception, fertilite, sexualite … 1999 11 citas

DNA repair enhancement by a combined supplement of carotenoids, nicotinamide, and zinc. Other

Cancer detection and … 1998 22 citas

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Dosificaciones de uso común

hairloss:: 1-2 tsp/day or topical application

Límite superior: Not established

Dosificaciones estudiadas en la investigación

Dosificación	Duración	Efecto	N
80 mg/kg	--	Neutral	--
Zinc, glutamine, other supplements	--	Positive	--
160 mg/kg	50 weeks	Positive	--
1%	--	Mixed	--
None	--	Positive	--
black seed oil 0.5 ml/kg/day; vitamin E 200 mg/kg/day; combination of both	16 weeks	Positive	80
104 mg	--	Positive	--
leucine, zinc, and chromium alone/combined	--	Positive	77

Mejor momento para tomar: Oral: with meals; Topical: massage into scalp and leave for 30 minutes before washing

Safety & Side Effects

Efectos secundarios reportados

⚠ Contact dermatitis when applied topically
⚠ Gastrointestinal discomfort
⚠ May lower blood sugar levels
⚠ Possible allergic reactions

Interacciones conocidas

● Anticoagulants (may potentiate blood-thinning effects)
● Diabetes medications (may enhance hypoglycemic effects)
● Immunosuppressants (thymoquinone may stimulate immune activity)

Ingesta máxima tolerable: Not established

Consulte siempre a su profesional de salud antes de comenzar cualquier suplemento.Siempre consulte a su profesional de salud antes de comenzar cualquier suplemento.

Frequently Asked Questions

Does Aceite de Semilla Negra help with Alopecia Areata?

Based on 25 studies with 1,327 participants, there is strong evidence from multiple clinical trials that Aceite de Semilla Negra may support Alopecia Areata management. Our evidence grade is A (Strong Evidence).

How much Aceite de Semilla Negra should I take for Alopecia Areata?

Studies have used various dosages. A commonly studied range is 1-2 tsp/day or topical application. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Aceite de Semilla Negra?

Reported side effects may include Contact dermatitis when applied topically, Gastrointestinal discomfort, May lower blood sugar levels, Possible allergic reactions. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Aceite de Semilla Negra and Alopecia Areata?

We rate the evidence as Grade A (Strong Evidence). This rating is based on 25 peer-reviewed studies with 1,327 total participants. The overall direction of effect is mixed.

Related Evidence

Otros ingredientes para Alopecia Areata

Minoxidil A Vitamina D A Terapia PRP A Microagujación A Ginseng C Zinc F

Aceite de Semilla Negra para otras condiciones

Telogen Effluvium A

Veredicto rápido

Basado en 25 estudios (4 RCTs) con 696 participantes en total. 24/25 estudios muestran efectos positivos.

Evidence Strength92%

High confidence

Desglose de estudios

RCT (4)Meta (0)Other (21)

Comparar alternativas

Vea cómo se comparan otros ingredientes para esta condición.

Ver todos los ingredientes para Alopecia Areata

Más información

Aviso legal FDA: Estas declaraciones no han sido evaluadas por la Food and Drug Administration. Los productos y la información en este sitio web no están destinados a diagnosticar, tratar, curar ni prevenir ninguna enfermedad. Las calificaciones de evidencia presentadas se basan en nuestro análisis de investigación publicada revisada por pares y no constituyen consejo médico. Siempre consulte a su profesional de salud antes de comenzar cualquier régimen de suplementos.