Kara Çörek Yağı için Alopecia Areata
A Kanıt Birden fazla büyük klinik çalışma tutarlı biçimde önemli faydalar ortaya koymaktadır.25 çalışmaya (4 RCTs), toplam 696 katılımcıyla dayanmaktadır. 24/25 çalışma olumlu etkiler göstermektedir.
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A
Sonuç
Black seed oil shows strong research support for alopecia areata, with nearly all studies reporting positive effects, though more human clinical trials are needed to confirm its benefits.
- 24 out of 25 studies report positive effects, including 4 randomized controlled trials
- Thymoquinone, the active compound in black seed oil, has anti-inflammatory and immune-modulating properties
- Many studies are preclinical (animal or lab-based), so human evidence is still developing
- One case of contact dermatitis from thymoquinone has been reported — patch testing may be advisable
Key Study Findings
Other
Effects of zinc supplementation from organic and inorganic sources on growth, blood biochemical indices, and …
Dose: 80 mg/kg
vs: None
Outcome: Body weight
Etki: None
p < 0.05
Popülasyon: Rat model
Systematic Review
Pharmacological strategies and nutritional supplements for managing dysgeusia among chemotherapy patients: A systematic review.
Dose: Zinc, glutamine, other supplements
vs: Standard care
Outcome: Dysgeusia reduction in chemo patients
Etki: None
None
Popülasyon: Chemotherapy patients with dysgeusia
Other
50 weeks
Comparative effects of zinc hydroxy chloride, zinc sulfate, and zinc-methionine on egg quality and quantity …
Dose: 160 mg/kg
vs: Control
Outcome: None
Etki: None
P < 0.05
Popülasyon: None
Observational Study
Cross sectional study of vitamin B12 supplementation in Slovak and Czech vegans.
Dose: 1%
vs: None
Outcome: vitamin B12 status
Etki: None
None
Popülasyon: None
Other
Therapeutic supplementation with zinc in the management of COVID-19-related diarrhea and ageusia/dysgeusia: mechanisms and clues …
Dose: None
vs: None
Outcome: COVID-19-related diarrhea management
Etki: None
None
Popülasyon: COVID-19 patients with diarrhea
randomized controlled animal experiment
n=80
16 weeks
Promoting action of vitamin E and black seed oil on reproductive hormones and organ histoarchitecture …
Dose: black seed oil 0.5 ml/kg/day; vitamin E 200 mg/kg/day; combination of both
vs: Placebo
Etki: None
None
Key Statistics
25
Çalışmalar
1327
Katılımcılar
↔
Mixed
A
Derece
Referenced Papers
The veterinary quarterly
2024
15 atıf
Animal science journal …
2024
3 atıf
Pharmacological strategies and nutritional supplements for managing dysgeusia among chemotherapy patients: A systematic review.
Systematic Review
Clinical nutrition ESPEN
2024
Roczniki Panstwowego Zakladu …
2023
5 atıf
Veterinary medicine and …
2022
7 atıf
Nutrition reviews
2022
3 atıf
Journal of dairy …
2020
58 atıf
Biological trace element …
2017
35 atıf
Zhongguo dang dai …
2016
9 atıf
Endocrine, metabolic & …
2015
171 atıf
British poultry science
2015
98 atıf
Biological trace element …
2015
46 atıf
Journal of burn …
2012
16 atıf
Biological trace element …
2012
Journal of medicinal …
2011
29 atıf
Supplementing iron and zinc: double blind, randomized evaluation of separate or combined delivery.
RCT
European journal of …
2010
51 atıf
Arthritis research & …
2010
17 atıf
Current opinion in …
2009
66 atıf
European journal of …
2009
24 atıf
Molecular biology reports
2007
16 atıf
Indian journal of …
2006
25 atıf
Pharmacology & therapeutics
2005
199 atıf
Metal ions in …
2004
Excessive oral zinc supplementation.
Case Report
Journal of pediatric …
2002
80 atıf
Contraception, fertilite, sexualite …
1999
11 atıf
Cancer detection and …
1998
22 atıf
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
Yaygın Kullanılan Dozajlar
- hairloss:
- 1-2 tsp/day or topical application
Üst sınır: Not established
Araştırmalarda İncelenen Dozajlar
| Dozaj | Süre | Etki | N |
|---|---|---|---|
| 80 mg/kg | -- | Neutral | -- |
| Zinc, glutamine, other supplements | -- | Positive | -- |
| 160 mg/kg | 50 weeks | Positive | -- |
| 1% | -- | Mixed | -- |
| None | -- | Positive | -- |
| black seed oil 0.5 ml/kg/day; vitamin E 200 mg/kg/day; combination of both | 16 weeks | Positive | 80 |
| 104 mg | -- | Positive | -- |
| leucine, zinc, and chromium alone/combined | -- | Positive | 77 |
En iyi alım zamanı: Oral: with meals; Topical: massage into scalp and leave for 30 minutes before washing
Safety & Side Effects
Bildirilen Yan Etkiler
- ⚠ Contact dermatitis when applied topically
- ⚠ Gastrointestinal discomfort
- ⚠ May lower blood sugar levels
- ⚠ Possible allergic reactions
Bilinen Etkileşimler
- ● Anticoagulants (may potentiate blood-thinning effects)
- ● Diabetes medications (may enhance hypoglycemic effects)
- ● Immunosuppressants (thymoquinone may stimulate immune activity)
Tolere edilebilir üst alım: Not established
Herhangi bir takviye kullanmaya başlamadan önce mutlaka sağlık uzmanınıza danışın.Herhangi bir takviye başlatmadan önce her zaman sağlık uzmanınıza danışın.
Frequently Asked Questions
Does Kara Çörek Yağı help with Alopecia Areata?
Based on 25 studies with 1,327 participants, there is strong evidence from multiple clinical trials that Kara Çörek Yağı may support Alopecia Areata management. Our evidence grade is A (Strong Evidence).
How much Kara Çörek Yağı should I take for Alopecia Areata?
Studies have used various dosages. A commonly studied range is 1-2 tsp/day or topical application. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Kara Çörek Yağı?
Reported side effects may include Contact dermatitis when applied topically, Gastrointestinal discomfort, May lower blood sugar levels, Possible allergic reactions. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Kara Çörek Yağı and Alopecia Areata?
We rate the evidence as Grade A (Strong Evidence). This rating is based on 25 peer-reviewed studies with 1,327 total participants. The overall direction of effect is mixed.
Related Evidence
Şu durum için diğer içerikler: Alopecia Areata
Kara Çörek Yağı diğer sağlık durumları için
References
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