Huile de nigelle pour Alopecia Areata
A Preuves Plusieurs grands essais cliniques montrent de manière constante des bénéfices significatifs.Basé sur 25 études (4 RCTs) avec 696 participants au total. 24/25 études montrent des effets positifs.
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A
En conclusion
Black seed oil shows strong research support for alopecia areata, with nearly all studies reporting positive effects, though more human clinical trials are needed to confirm its benefits.
- 24 out of 25 studies report positive effects, including 4 randomized controlled trials
- Thymoquinone, the active compound in black seed oil, has anti-inflammatory and immune-modulating properties
- Many studies are preclinical (animal or lab-based), so human evidence is still developing
- One case of contact dermatitis from thymoquinone has been reported — patch testing may be advisable
Key Study Findings
Other
Effects of zinc supplementation from organic and inorganic sources on growth, blood biochemical indices, and …
Dose: 80 mg/kg
vs: None
Outcome: Body weight
Effet: None
p < 0.05
Population: Rat model
Systematic Review
Pharmacological strategies and nutritional supplements for managing dysgeusia among chemotherapy patients: A systematic review.
Dose: Zinc, glutamine, other supplements
vs: Standard care
Outcome: Dysgeusia reduction in chemo patients
Effet: None
None
Population: Chemotherapy patients with dysgeusia
Other
50 weeks
Comparative effects of zinc hydroxy chloride, zinc sulfate, and zinc-methionine on egg quality and quantity …
Dose: 160 mg/kg
vs: Control
Outcome: None
Effet: None
P < 0.05
Population: None
Observational Study
Cross sectional study of vitamin B12 supplementation in Slovak and Czech vegans.
Dose: 1%
vs: None
Outcome: vitamin B12 status
Effet: None
None
Population: None
Other
Therapeutic supplementation with zinc in the management of COVID-19-related diarrhea and ageusia/dysgeusia: mechanisms and clues …
Dose: None
vs: None
Outcome: COVID-19-related diarrhea management
Effet: None
None
Population: COVID-19 patients with diarrhea
randomized controlled animal experiment
n=80
16 weeks
Promoting action of vitamin E and black seed oil on reproductive hormones and organ histoarchitecture …
Dose: black seed oil 0.5 ml/kg/day; vitamin E 200 mg/kg/day; combination of both
vs: Placebo
Effet: None
None
Key Statistics
25
Études
1327
Participants
↔
Mixed
A
Note
Referenced Papers
The veterinary quarterly
2024
15 citations
Animal science journal …
2024
3 citations
Pharmacological strategies and nutritional supplements for managing dysgeusia among chemotherapy patients: A systematic review.
Systematic Review
Clinical nutrition ESPEN
2024
Roczniki Panstwowego Zakladu …
2023
5 citations
Veterinary medicine and …
2022
7 citations
Nutrition reviews
2022
3 citations
Journal of dairy …
2020
58 citations
Biological trace element …
2017
35 citations
Zhongguo dang dai …
2016
9 citations
Endocrine, metabolic & …
2015
171 citations
British poultry science
2015
98 citations
Biological trace element …
2015
46 citations
Journal of burn …
2012
16 citations
Biological trace element …
2012
Journal of medicinal …
2011
29 citations
Supplementing iron and zinc: double blind, randomized evaluation of separate or combined delivery.
RCT
European journal of …
2010
51 citations
Arthritis research & …
2010
17 citations
Current opinion in …
2009
66 citations
European journal of …
2009
24 citations
Molecular biology reports
2007
16 citations
Indian journal of …
2006
25 citations
Pharmacology & therapeutics
2005
199 citations
Metal ions in …
2004
Excessive oral zinc supplementation.
Case Report
Journal of pediatric …
2002
80 citations
Contraception, fertilite, sexualite …
1999
11 citations
Cancer detection and …
1998
22 citations
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
Posologies couramment utilisées
- hairloss:
- 1-2 tsp/day or topical application
Limite supérieure : Not established
Posologies étudiées dans la recherche
| Posologie | Durée | Effet | N |
|---|---|---|---|
| 80 mg/kg | -- | Neutral | -- |
| Zinc, glutamine, other supplements | -- | Positive | -- |
| 160 mg/kg | 50 weeks | Positive | -- |
| 1% | -- | Mixed | -- |
| None | -- | Positive | -- |
| black seed oil 0.5 ml/kg/day; vitamin E 200 mg/kg/day; combination of both | 16 weeks | Positive | 80 |
| 104 mg | -- | Positive | -- |
| leucine, zinc, and chromium alone/combined | -- | Positive | 77 |
Moment optimal de prise : Oral: with meals; Topical: massage into scalp and leave for 30 minutes before washing
Safety & Side Effects
Effets indésirables signalés
- ⚠ Contact dermatitis when applied topically
- ⚠ Gastrointestinal discomfort
- ⚠ May lower blood sugar levels
- ⚠ Possible allergic reactions
Interactions connues
- ● Anticoagulants (may potentiate blood-thinning effects)
- ● Diabetes medications (may enhance hypoglycemic effects)
- ● Immunosuppressants (thymoquinone may stimulate immune activity)
Apport maximal tolérable : Not established
Consultez toujours votre professionnel de santé avant de commencer tout complément alimentaire.Consultez toujours votre professionnel de santé avant de commencer tout complément alimentaire.
Frequently Asked Questions
Does Huile de nigelle help with Alopecia Areata?
Based on 25 studies with 1,327 participants, there is strong evidence from multiple clinical trials that Huile de nigelle may support Alopecia Areata management. Our evidence grade is A (Strong Evidence).
How much Huile de nigelle should I take for Alopecia Areata?
Studies have used various dosages. A commonly studied range is 1-2 tsp/day or topical application. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Huile de nigelle?
Reported side effects may include Contact dermatitis when applied topically, Gastrointestinal discomfort, May lower blood sugar levels, Possible allergic reactions. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Huile de nigelle and Alopecia Areata?
We rate the evidence as Grade A (Strong Evidence). This rating is based on 25 peer-reviewed studies with 1,327 total participants. The overall direction of effect is mixed.
Related Evidence
Autres ingrédients pour Alopecia Areata
Huile de nigelle pour d'autres pathologies
References
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