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Schwarzkümmelöl für Alopecia Areata

A

Basierend auf 25 Studien (4 RCTs) mit 696 Teilnehmern insgesamt. 24/25 Studien zeigen positive Effekte.

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A

Fazit

Black seed oil shows strong research support for alopecia areata, with nearly all studies reporting positive effects, though more human clinical trials are needed to confirm its benefits.

  • 24 out of 25 studies report positive effects, including 4 randomized controlled trials
  • Thymoquinone, the active compound in black seed oil, has anti-inflammatory and immune-modulating properties
  • Many studies are preclinical (animal or lab-based), so human evidence is still developing
  • One case of contact dermatitis from thymoquinone has been reported — patch testing may be advisable

Key Study Findings

Other
Effects of zinc supplementation from organic and inorganic sources on growth, blood biochemical indices, and …
Dose: 80 mg/kg vs.: None Outcome: Body weight Wirkung: None p < 0.05

Population: Rat model

Systematic Review
Pharmacological strategies and nutritional supplements for managing dysgeusia among chemotherapy patients: A systematic review.
Dose: Zinc, glutamine, other supplements vs.: Standard care Outcome: Dysgeusia reduction in chemo patients Wirkung: None None

Population: Chemotherapy patients with dysgeusia

Other 50 weeks
Comparative effects of zinc hydroxy chloride, zinc sulfate, and zinc-methionine on egg quality and quantity …
Dose: 160 mg/kg vs.: Control Outcome: None Wirkung: None P < 0.05

Population: None

Observational Study
Cross sectional study of vitamin B12 supplementation in Slovak and Czech vegans.
Dose: 1% vs.: None Outcome: vitamin B12 status Wirkung: None None

Population: None

Other
Therapeutic supplementation with zinc in the management of COVID-19-related diarrhea and ageusia/dysgeusia: mechanisms and clues …
Dose: None vs.: None Outcome: COVID-19-related diarrhea management Wirkung: None None

Population: COVID-19 patients with diarrhea

randomized controlled animal experiment n=80 16 weeks
Promoting action of vitamin E and black seed oil on reproductive hormones and organ histoarchitecture …
Dose: black seed oil 0.5 ml/kg/day; vitamin E 200 mg/kg/day; combination of both vs.: Placebo Wirkung: None None

Key Statistics

25

Studien

1327

Teilnehmer

Mixed

A

Bewertung

Referenced Papers

Roczniki Panstwowego Zakladu … 2023 5 Zitierungen
Endocrine, metabolic & … 2015 171 Zitierungen
Journal of burn … 2012 16 Zitierungen
Journal of medicinal … 2011 29 Zitierungen
Molecular biology reports 2007 16 Zitierungen
Indian journal of … 2006 25 Zitierungen
Journal of pediatric … 2002 80 Zitierungen
Contraception, fertilite, sexualite … 1999 11 Zitierungen

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Übliche Dosierungen

hairloss:
1-2 tsp/day or topical application

Obergrenze: Not established

In der Forschung untersuchte Dosierungen

Dosierung Dauer Wirkung N
80 mg/kg -- Neutral --
Zinc, glutamine, other supplements -- Positive --
160 mg/kg 50 weeks Positive --
1% -- Mixed --
None -- Positive --
black seed oil 0.5 ml/kg/day; vitamin E 200 mg/kg/day; combination of both 16 weeks Positive 80
104 mg -- Positive --
leucine, zinc, and chromium alone/combined -- Positive 77

Beste Einnahmezeit: Oral: with meals; Topical: massage into scalp and leave for 30 minutes before washing

Safety & Side Effects

Gemeldete Nebenwirkungen

  • Contact dermatitis when applied topically
  • Gastrointestinal discomfort
  • May lower blood sugar levels
  • Possible allergic reactions

Bekannte Wechselwirkungen

  • Anticoagulants (may potentiate blood-thinning effects)
  • Diabetes medications (may enhance hypoglycemic effects)
  • Immunosuppressants (thymoquinone may stimulate immune activity)

Tolerierbare Höchstaufnahmemenge: Not established

Konsultieren Sie immer Ihren Arzt, bevor Sie ein Nahrungsergänzungsmittel einnehmen.Konsultieren Sie immer Ihren Arzt, bevor Sie ein Nahrungsergänzungsmittel einnehmen.

Frequently Asked Questions

Does Schwarzkümmelöl help with Alopecia Areata?
Based on 25 studies with 1,327 participants, there is strong evidence from multiple clinical trials that Schwarzkümmelöl may support Alopecia Areata management. Our evidence grade is A (Strong Evidence).
How much Schwarzkümmelöl should I take for Alopecia Areata?
Studies have used various dosages. A commonly studied range is 1-2 tsp/day or topical application. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Schwarzkümmelöl?
Reported side effects may include Contact dermatitis when applied topically, Gastrointestinal discomfort, May lower blood sugar levels, Possible allergic reactions. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Schwarzkümmelöl and Alopecia Areata?
We rate the evidence as Grade A (Strong Evidence). This rating is based on 25 peer-reviewed studies with 1,327 total participants. The overall direction of effect is mixed.

Related Evidence

Schwarzkümmelöl für andere Beschwerden

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