الزنك لـ الثعلبة الأندروجينية
Aبناءً على 29 دراسة (1 meta-analysis, 3 RCTs) بمشاركة 49,138 مشاركًا إجمالاً. النتائج متباينة بين الدراسات.
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A
الخلاصة
Research on zinc for androgenetic alopecia is mixed — while zinc is important for hair follicle health, supplementation alone has not been clearly shown to improve pattern hair loss.
- Mixed results across 29 studies, including a meta-analysis showing inconsistent findings
- Some studies find lower zinc in people with pattern hair loss, others do not
- Zinc is usually studied as part of multi-ingredient formulas, making its individual contribution unclear
- Supplementation may only help if a zinc deficiency is confirmed
Key Study Findings
animal study
Protective mechanisms of zinc and/or selenium supplementation against BPA-induced male and offspring reproductive toxicity: Insights …
Dose: zinc and/or selenium supplementation; doses not specified in abstract
مقابل: Placebo
التأثير: None
None
Review
Minerals and Trace Elements: Key Protectors of Skin Health and Defenders against Skin Disorders.
Dose: None
مقابل: Placebo
التأثير: None
None
review
[Nutrition in improving sleep quality and fighting insomnia].
Dose: tryptophan, carbohydrates, omega-3, vitamins (B6, B12, folate, niacin, D, C, beta-carotene), mineral
مقابل: Placebo
التأثير: None
None
cross-sectional study
Zinc Status in Kurdish Adults With Hair Loss.
Dose: None
مقابل: Placebo
التأثير: None
None
systematic_review
Micronutrients and Androgenetic Alopecia: A Systematic Review.
Dose: variable across included studies
مقابل: Placebo
التأثير: vitamin B, D, iron, zinc deficiencies associated with increased AGA risk; supplementation showed pot
None
in vitro study
Regulatory Effects of Thai Rice By-Product Extracts from Oryza sativa L. cv. Bue Bang 3 …
Dose: not specified
مقابل: Placebo
التأثير: melanin production 130.18 ± 9.13% of control; NO secretion 1.43 ± 0.05 µM
p > 0.05 (vs theophylline, no
Key Statistics
33
الدراسات
49138
المشاركون
↔
Mixed
A
التقييم
Referenced Papers
Environment international
2026
Minerals and Trace Elements: Key Protectors of Skin Health and Defenders against Skin Disorders.
Review
Current medicinal chemistry
2025
5 اقتباسات
Nutricion hospitalaria
2025
Micronutrients and Androgenetic Alopecia: A Systematic Review.
Systematic Review
Molecular nutrition & …
2024
7 اقتباسات
Cureus
2024
1 اقتباسات
Plants (Basel, Switzerland)
2023
14 اقتباسات
Italian journal of …
2023
3 اقتباسات
European journal of …
2022
34 اقتباسات
Journal of cosmetic …
2022
11 اقتباسات
Human nutrition & …
2022
9 اقتباسات
JAAD international
2022
6 اقتباسات
Association between serum zinc levels and androgenetic alopecia: a systematic review and meta-analysis.
Meta-Analysis
Journal of cosmetic …
2022
5 اقتباسات
Dermatology reports
2022
4 اقتباسات
Italian journal of …
2022
2 اقتباسات
International journal of …
2021
23 اقتباسات
Diagnostics (Basel, Switzerland)
2020
13 اقتباسات
Pharmacological reports : …
2020
7 اقتباسات
Skinmed
2020
Female Pattern Hair Loss and Androgen Excess: A Report From the Multidisciplinary Androgen Excess and PCOS Committee.
Meta-Analysis
The Journal of …
2019
101 اقتباسات
Journal of cosmetic …
2019
15 اقتباسات
Indian journal of …
2018
26 اقتباسات
International journal of …
2017
43 اقتباسات
Indian journal of …
2017
10 اقتباسات
International journal of …
2016
28 اقتباسات
Acta dermatovenerologica Croatica …
2016
6 اقتباسات
Journal of trace …
2014
62 اقتباسات
Journal of drugs …
2014
26 اقتباسات
Annals of dermatology
2013
114 اقتباسات
Clinical and experimental …
2009
34 اقتباسات
Georgian medical news
2007
Journal of the …
2006
255 اقتباسات
International journal of …
2002
53 اقتباسات
Clinical and experimental …
1989
140 اقتباسات
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
الجرعات الشائعة
- general:
- 8-11 mg/day
- hairloss:
- 15-30 mg/day
الحد الأعلى: 40 mg/day
الجرعات المدروسة في الأبحاث
| الجرعة | المدة | التأثير | ن |
|---|---|---|---|
| zinc and/or selenium supplementation; doses not specified in abstract | -- | Positive | -- |
| None | -- | Positive | -- |
| tryptophan, carbohydrates, omega-3, vitamins (B6, B12, folate, niacin, D, C, beta-carotene), mineral | -- | Positive | -- |
| None | -- | Neutral | -- |
| variable across included studies | -- | Mixed | -- |
| not specified | -- | Positive | -- |
| Daily tablet (L-cystine, L-methionine, liposomal glutathione, zinc, copper, iron, selenium, ubidecar | 24 weeks | Positive | 20 |
| Topical lotion containing zinc and arginine (concentration not specified) | 23 weeks | Positive | 40 |
أفضل وقت للتناول: With meals to minimize stomach upset; separate from iron and calcium by 2 hours
Safety & Side Effects
الآثار الجانبية المُبلّغ عنها
- ⚠ Nausea and vomiting (especially on an empty stomach)
- ⚠ Metallic taste in the mouth
- ⚠ Copper depletion with chronic high-dose use
- ⚠ Headache and diarrhea
التفاعلات المعروفة
- ● Copper supplements (zinc inhibits copper absorption at doses >40 mg/day)
- ● Tetracycline and quinolone antibiotics (mutual absorption reduction)
- ● Penicillamine (zinc reduces absorption of this rheumatoid arthritis drug)
الحد الأقصى المسموح به: 40 mg/day
استشر مقدم الرعاية الصحية دائماً قبل البدء بأي مكمل غذائي.
Frequently Asked Questions
Does الزنك help with الثعلبة الأندروجينية?
Based on 33 studies with 49,138 participants, there is strong evidence from multiple clinical trials that الزنك may support الثعلبة الأندروجينية management. Our evidence grade is A (Strong Evidence).
How much الزنك should I take for الثعلبة الأندروجينية?
Studies have used various dosages. A commonly studied range is 8-11 mg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of الزنك?
Reported side effects may include Nausea and vomiting (especially on an empty stomach), Metallic taste in the mouth, Copper depletion with chronic high-dose use, Headache and diarrhea. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for الزنك and الثعلبة الأندروجينية?
We rate the evidence as Grade A (Strong Evidence). This rating is based on 33 peer-reviewed studies with 49,138 total participants. The overall direction of effect is mixed.
Related Evidence
مكونات أخرى لـ الثعلبة الأندروجينية
الزنك لحالات أخرى
إخلاء مسؤولية FDA: لم تُقيَّم هذه البيانات من قبل إدارة الغذاء والدواء (FDA). لا تهدف المنتجات والمعلومات الواردة في هذا الموقع إلى تشخيص أو علاج أو شفاء أو الوقاية من أي مرض. تستند تقييمات الأدلة المعروضة إلى تحليلنا للأبحاث المحكّمة المنشورة ولا تُشكّل نصيحة طبية. استشر مقدم الرعاية الصحية دائماً قبل البدء بأي نظام مكملات.