维生素 D 用于女性型脱发

Q: Does 维生素 D help with 女性型脱发?

Based on 19 studies with 15,494 participants, there is strong evidence from multiple clinical trials that 维生素 D may support 女性型脱发 management. Our evidence grade is A (Strong Evidence).

Q: How much 维生素 D should I take for 女性型脱发?

Studies have used various dosages. A commonly studied range is 600-800 IU/day. Always consult your healthcare provider before starting any supplement regimen.

Q: Are there side effects of 维生素 D?

Reported side effects may include Hypercalcemia at very high doses (nausea, vomiting, weakness), Kidney stones with excessive long-term use, Constipation, Metallic taste. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

Q: How strong is the evidence for 维生素 D and 女性型脱发?

We rate the evidence as Grade A (Strong Evidence). This rating is based on 19 peer-reviewed studies with 15,494 total participants. The overall direction of effect is mixed.

A 证据多项大型临床试验一致显示出显著的益处。

基于18项研究（2项荟萃分析），共15,494名参与者。各研究结果不一。

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结论

Research shows that women with pattern hair loss often have lower vitamin D levels, but supplementing with vitamin D alone is unlikely to significantly improve this condition — it may be one supportive factor among many.

Lower vitamin D levels are consistently found in women with pattern hair loss
Supplementation alone is less effective than established options like minoxidil
Vitamin D receptor gene variants may influence susceptibility
Maintaining adequate vitamin D may support overall hair health but is not a standalone solution

Key Study Findings

narrative review

Addressing the Root Causes of Female Hair Loss and Non-Pharmaceutical Interventions.

Dose: None vs: Placebo 效果: None None

Meta-analysis

Vitamin D deficiency in non-scarring and scarring alopecias: a systematic review and meta-analysis.

Dose: None vs: Placebo 效果: OR=2.84 (AA vs controls), OR=5.24 (FPHL vs controls) p<0.01

cross-sectional observational n=120

Filling the Gaps: Vitamin D Status in Diffuse Hair Fall Among Pakistanis.

Dose: None vs: Placebo 效果: 79.17% of patients with diffuse hair fall were vitamin D3 deficient (mean 17.33 ± 5.43 ng/mL) None

meta_analysis n=10670

Serum 25 hydroxyvitamin D in non-scarring alopecia: A systematic review and meta-analysis.

Dose: not applicable (observational meta-analysis) vs: Placebo 效果: WMD -7.29 ng/mL (95% CI -9.21, -5.38); OR for vitamin D deficiency 3.11 (95% CI 2.29, 4.22) not explicitly stated; CI does

Case-control n=165

The development of non-scarring alopecia in women who wear the hijab.

Dose: None vs: Placebo 效果: OR=4.1 (95% CI 1.2-14.1) for vitamin D deficiency and telogen effluvium p=0.02

Other

Serum ferritin and vitamin D levels in women with non-scarring alopecia.

Dose: None vs: None Outcome: None 效果: None None

研究人群: Women with non-scarring alopecia

Key Statistics

研究数量

15494

受试者

↔

Mixed

等级

Referenced Papers

Addressing the Root Causes of Female Hair Loss and Non-Pharmaceutical Interventions. Review

Journal of drugs … 2025

Serum 25 hydroxyvitamin D in non-scarring alopecia: A systematic review and meta-analysis. Meta-Analysis

Journal of cosmetic … 2024 7 次引用

Vitamin D deficiency in non-scarring and scarring alopecias: a systematic review and meta-analysis. Systematic Review

Frontiers in nutrition 2024 4 次引用

Filling the Gaps: Vitamin D Status in Diffuse Hair Fall Among Pakistanis. Other

Dermatology practical & … 2024

The development of non-scarring alopecia in women who wear the hijab. Other

Archives of dermatological … 2023 3 次引用

Treatment with oral vitamin D alone, topical minoxidil, or combination of both in patients with female pattern hair loss: A … Other

Journal of cosmetic … 2022 10 次引用

Serum ferritin and vitamin D levels in women with non-scarring alopecia. Other

Journal of cosmetic … 2022 4 次引用

Role of vitamin D in hair loss: A short review. Review

Journal of cosmetic … 2021 44 次引用

Study of serum vitamin D levels in men with premature androgenetic alopecia. Other

International journal of … 2020 18 次引用

Serum 25 hydroxyvitamin D levels in alopecia areata, female pattern hair loss, and male androgenetic alopecia in a Chinese population. Other

Journal of cosmetic … 2020 17 次引用

Trichotillomania associated with a 25-hydroxy vitamin D deficiency: A case report. Case Report

The mental health … 2020 7 次引用

Vitamin D Receptor Gene Polymorphisms Taq-1 and Cdx-1 in Female Pattern Hair Loss. Other

Indian journal of … 2020 5 次引用

Female Pattern Hair Loss and Androgen Excess: A Report From the Multidisciplinary Androgen Excess and PCOS Committee. Meta-Analysis

The Journal of … 2019 101 次引用

NonScarring Diffuse Hair Loss in Women: a Clinico-Etiological Study from tertiary care center in North-West India. Observational

Journal of cosmetic … 2019 25 次引用

Genetics and other factors in the aetiology of female pattern hair loss. Review

Experimental dermatology 2017 82 次引用

The Role of Vitamin D in Non-Scarring Alopecia. Review

International journal of … 2017 61 次引用

Serum Vitamin D3 Level in Patients with Female Pattern Hair Loss. Other

International journal of … 2016 42 次引用

Female Pattern Hair Loss: A Retrospective Study in a Tertiary Referral Center. Other

International journal of … 2016 28 次引用

Serum ferritin and vitamin d in female hair loss: do they play a role? Other

Skin pharmacology and … 2013 127 次引用

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

常用剂量

general:: 600-800 IU/day
deficiency:: 1,000-5,000 IU/day

上限： 4,000 IU/day

研究中使用的剂量

剂量	持续时间	效果	N
None	--	Positive	--
None	--	Negative	--
None	--	Neutral	120
not applicable (observational meta-analysis)	--	Negative	10670
None	--	Positive	165
None	--	Mixed	--
None	--	Negative	--
1000 IU vitamin D3 daily	16 weeks	Positive	2

最佳服用时间： With a fat-containing meal for optimal absorption

Safety & Side Effects

已报告的副作用

⚠ Hypercalcemia at very high doses (nausea, vomiting, weakness)
⚠ Kidney stones with excessive long-term use
⚠ Constipation
⚠ Metallic taste

已知相互作用

● Thiazide diuretics (may increase risk of hypercalcemia)
● Corticosteroids (reduce vitamin D absorption and metabolism)
● Orlistat and cholestyramine (reduce fat-soluble vitamin absorption)

可耐受最高摄入量： 4,000 IU/day

在开始服用任何补充剂之前，请务必咨询您的医疗保健提供者。

Frequently Asked Questions

Does 维生素 D help with 女性型脱发?

Based on 19 studies with 15,494 participants, there is strong evidence from multiple clinical trials that 维生素 D may support 女性型脱发 management. Our evidence grade is A (Strong Evidence).

How much 维生素 D should I take for 女性型脱发?

Studies have used various dosages. A commonly studied range is 600-800 IU/day. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of 维生素 D?

Reported side effects may include Hypercalcemia at very high doses (nausea, vomiting, weakness), Kidney stones with excessive long-term use, Constipation, Metallic taste. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for 维生素 D and 女性型脱发?

We rate the evidence as Grade A (Strong Evidence). This rating is based on 19 peer-reviewed studies with 15,494 total participants. The overall direction of effect is mixed.

其他成分用于女性型脱发

米诺地尔（Minoxidil） A 螺内酯（Spironolactone） A 低能量激光疗法（LLLT） A Nutrafol A 锯棕榈 B

维生素 D 用于其他健康状况

斑秃 A 休止期脱发 F

快速结论

基于18项研究（2项荟萃分析），共15,494名参与者。各研究结果不一。

Evidence Strength92%

High confidence

研究分析

RCT (0)Meta (2)Other (17)

对比替代方案

查看其他成分针对该健康状况的对比结果。

查看所有成分用于女性型脱发

了解更多

References

[1] Adam Leavitt et al.. J Drugs Dermatol. 2025. Addressing the Root Causes of Female Hair Loss and Non-Pharmaceutical Interventions. doi:10.36849/JDD.8763 PubMed
[2] Yuling Chen et al.. J Cosmet Dermatol. 2024. Serum 25 hydroxyvitamin D in non-scarring alopecia: A systematic review and meta-analysis. doi:10.1111/jocd.16093 PubMed
[3] Tanat Yongpisarn et al.. Front Nutr. 2024. Vitamin D deficiency in non-scarring and scarring alopecias: a systematic review and meta-analysis. doi:10.3389/fnut.2024.1479337 PubMed
[4] Palwasha Jalil et al.. Dermatol Pract Concept. 2024. Filling the Gaps: Vitamin D Status in Diffuse Hair Fall Among Pakistanis. doi:10.5826/dpc.1404a232 PubMed
[5] Marissa S Ceresnie et al.. Arch Dermatol Res. 2023. The development of non-scarring alopecia in women who wear the hijab. doi:10.1007/s00403-023-02713-3 PubMed
[6] Ghada F R Hassan et al.. J Cosmet Dermatol. 2022. Treatment with oral vitamin D alone, topical minoxidil, or combination of both in patients with female pattern hair loss: A … doi:10.1111/jocd.14743 PubMed
[7] Marina de Queiroz et al.. J Cosmet Dermatol. 2022. Serum ferritin and vitamin D levels in women with non-scarring alopecia. doi:10.1111/jocd.14472 PubMed
[8] Kriteeka Saini et al.. J Cosmet Dermatol. 2021. Role of vitamin D in hair loss: A short review. doi:10.1111/jocd.14421 PubMed
[9] Sarita Sanke et al.. Int J Dermatol. 2020. Study of serum vitamin D levels in men with premature androgenetic alopecia. doi:10.1111/ijd.14982 PubMed
[10] Jun Zhao et al.. J Cosmet Dermatol. 2020. Serum 25 hydroxyvitamin D levels in alopecia areata, female pattern hair loss, and male androgenetic alopecia in a Chinese population. doi:10.1111/jocd.13396 PubMed
[11] Erika Titus-Lay et al.. Ment Health Clin. 2020. Trichotillomania associated with a 25-hydroxy vitamin D deficiency: A case report. doi:10.9740/mhc.2020.01.038 PubMed
[12] Iman Seleit et al.. Indian J Dermatol. 2020. Vitamin D Receptor Gene Polymorphisms Taq-1 and Cdx-1 in Female Pattern Hair Loss. doi:10.4103/ijd.IJD_482_18 PubMed
[13] Enrico Carmina et al.. J Clin Endocrinol Metab. 2019. Female Pattern Hair Loss and Androgen Excess: A Report From the Multidisciplinary Androgen Excess and PCOS Committee. doi:10.1210/jc.2018-02548 PubMed
[14] Kavita Poonia et al.. J Cosmet Dermatol. 2019. NonScarring Diffuse Hair Loss in Women: a Clinico-Etiological Study from tertiary care center in North-West India. doi:10.1111/jocd.12559 PubMed
[15] Silke Redler et al.. Exp Dermatol. 2017. Genetics and other factors in the aetiology of female pattern hair loss. doi:10.1111/exd.13373 PubMed
[16] Agnieszka Gerkowicz et al.. Int J Mol Sci. 2017. The Role of Vitamin D in Non-Scarring Alopecia. doi:10.3390/ijms18122653 PubMed
[17] Mahnaz Banihashemi et al.. Int J Trichology. 2016. Serum Vitamin D3 Level in Patients with Female Pattern Hair Loss. doi:10.4103/0974-7753.188965 PubMed
[18] Tee Wei Siah et al.. Int J Trichology. 2016. Female Pattern Hair Loss: A Retrospective Study in a Tertiary Referral Center. doi:10.4103/0974-7753.188033 PubMed
[19] H Rasheed et al.. Skin Pharmacol Physiol. 2013. Serum ferritin and vitamin d in female hair loss: do they play a role? doi:10.1159/000346698 PubMed

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维生素 D 用于 女性型脱发