فيتامين D لـ تساقط الشعر النمطي الأنثوي
A الأدلة تُظهر تجارب سريرية كبيرة متعددة باستمرار فوائد ملحوظة.بناءً على 18 دراسة (2 meta-analyses) بمشاركة 15,494 مشاركًا إجمالاً. النتائج متباينة بين الدراسات.
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A
الخلاصة
Research shows that women with pattern hair loss often have lower vitamin D levels, but supplementing with vitamin D alone is unlikely to significantly improve this condition — it may be one supportive factor among many.
- Lower vitamin D levels are consistently found in women with pattern hair loss
- Supplementation alone is less effective than established options like minoxidil
- Vitamin D receptor gene variants may influence susceptibility
- Maintaining adequate vitamin D may support overall hair health but is not a standalone solution
Key Study Findings
narrative review
Addressing the Root Causes of Female Hair Loss and Non-Pharmaceutical Interventions.
Dose: None
مقابل: Placebo
التأثير: None
None
Meta-analysis
Vitamin D deficiency in non-scarring and scarring alopecias: a systematic review and meta-analysis.
Dose: None
مقابل: Placebo
التأثير: OR=2.84 (AA vs controls), OR=5.24 (FPHL vs controls)
p<0.01
cross-sectional observational
n=120
Filling the Gaps: Vitamin D Status in Diffuse Hair Fall Among Pakistanis.
Dose: None
مقابل: Placebo
التأثير: 79.17% of patients with diffuse hair fall were vitamin D3 deficient (mean 17.33 ± 5.43 ng/mL)
None
meta_analysis
n=10670
Serum 25 hydroxyvitamin D in non-scarring alopecia: A systematic review and meta-analysis.
Dose: not applicable (observational meta-analysis)
مقابل: Placebo
التأثير: WMD -7.29 ng/mL (95% CI -9.21, -5.38); OR for vitamin D deficiency 3.11 (95% CI 2.29, 4.22)
not explicitly stated; CI does
Case-control
n=165
The development of non-scarring alopecia in women who wear the hijab.
Dose: None
مقابل: Placebo
التأثير: OR=4.1 (95% CI 1.2-14.1) for vitamin D deficiency and telogen effluvium
p=0.02
Other
Serum ferritin and vitamin D levels in women with non-scarring alopecia.
Dose: None
مقابل: None
Outcome: None
التأثير: None
None
المجتمع المدروس: Women with non-scarring alopecia
Key Statistics
19
الدراسات
15494
المشاركون
↔
Mixed
A
التقييم
Referenced Papers
Journal of drugs …
2025
Serum 25 hydroxyvitamin D in non-scarring alopecia: A systematic review and meta-analysis.
Meta-Analysis
Journal of cosmetic …
2024
7 اقتباسات
Vitamin D deficiency in non-scarring and scarring alopecias: a systematic review and meta-analysis.
Systematic Review
Frontiers in nutrition
2024
4 اقتباسات
Dermatology practical & …
2024
Archives of dermatological …
2023
3 اقتباسات
Journal of cosmetic …
2022
10 اقتباسات
Journal of cosmetic …
2022
4 اقتباسات
Journal of cosmetic …
2021
44 اقتباسات
International journal of …
2020
18 اقتباسات
Journal of cosmetic …
2020
17 اقتباسات
The mental health …
2020
7 اقتباسات
Indian journal of …
2020
5 اقتباسات
Female Pattern Hair Loss and Androgen Excess: A Report From the Multidisciplinary Androgen Excess and PCOS Committee.
Meta-Analysis
The Journal of …
2019
101 اقتباسات
NonScarring Diffuse Hair Loss in Women: a Clinico-Etiological Study from tertiary care center in North-West India.
Observational
Journal of cosmetic …
2019
25 اقتباسات
Experimental dermatology
2017
82 اقتباسات
International journal of …
2017
61 اقتباسات
International journal of …
2016
42 اقتباسات
International journal of …
2016
28 اقتباسات
Skin pharmacology and …
2013
127 اقتباسات
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
الجرعات الشائعة
- general:
- 600-800 IU/day
- deficiency:
- 1,000-5,000 IU/day
الحد الأعلى: 4,000 IU/day
الجرعات المدروسة في الأبحاث
| الجرعة | المدة | التأثير | ن |
|---|---|---|---|
| None | -- | Positive | -- |
| None | -- | Negative | -- |
| None | -- | Neutral | 120 |
| not applicable (observational meta-analysis) | -- | Negative | 10670 |
| None | -- | Positive | 165 |
| None | -- | Mixed | -- |
| None | -- | Negative | -- |
| 1000 IU vitamin D3 daily | 16 weeks | Positive | 2 |
أفضل وقت للتناول: With a fat-containing meal for optimal absorption
Safety & Side Effects
الآثار الجانبية المُبلّغ عنها
- ⚠ Hypercalcemia at very high doses (nausea, vomiting, weakness)
- ⚠ Kidney stones with excessive long-term use
- ⚠ Constipation
- ⚠ Metallic taste
التفاعلات المعروفة
- ● Thiazide diuretics (may increase risk of hypercalcemia)
- ● Corticosteroids (reduce vitamin D absorption and metabolism)
- ● Orlistat and cholestyramine (reduce fat-soluble vitamin absorption)
الحد الأقصى المسموح به: 4,000 IU/day
استشر مقدم الرعاية الصحية دائماً قبل البدء بأي مكمل غذائي.
Frequently Asked Questions
Does فيتامين D help with تساقط الشعر النمطي الأنثوي?
Based on 19 studies with 15,494 participants, there is strong evidence from multiple clinical trials that فيتامين D may support تساقط الشعر النمطي الأنثوي management. Our evidence grade is A (Strong Evidence).
How much فيتامين D should I take for تساقط الشعر النمطي الأنثوي?
Studies have used various dosages. A commonly studied range is 600-800 IU/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of فيتامين D?
Reported side effects may include Hypercalcemia at very high doses (nausea, vomiting, weakness), Kidney stones with excessive long-term use, Constipation, Metallic taste. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for فيتامين D and تساقط الشعر النمطي الأنثوي?
We rate the evidence as Grade A (Strong Evidence). This rating is based on 19 peer-reviewed studies with 15,494 total participants. The overall direction of effect is mixed.
Related Evidence
مكونات أخرى لـ تساقط الشعر النمطي الأنثوي
فيتامين D لحالات أخرى
References
- [1] Adam Leavitt et al.. J Drugs Dermatol. 2025. Addressing the Root Causes of Female Hair Loss and Non-Pharmaceutical Interventions. doi:10.36849/JDD.8763 PubMed
- [2] Yuling Chen et al.. J Cosmet Dermatol. 2024. Serum 25 hydroxyvitamin D in non-scarring alopecia: A systematic review and meta-analysis. doi:10.1111/jocd.16093 PubMed
- [3] Tanat Yongpisarn et al.. Front Nutr. 2024. Vitamin D deficiency in non-scarring and scarring alopecias: a systematic review and meta-analysis. doi:10.3389/fnut.2024.1479337 PubMed
- [4] Palwasha Jalil et al.. Dermatol Pract Concept. 2024. Filling the Gaps: Vitamin D Status in Diffuse Hair Fall Among Pakistanis. doi:10.5826/dpc.1404a232 PubMed
- [5] Marissa S Ceresnie et al.. Arch Dermatol Res. 2023. The development of non-scarring alopecia in women who wear the hijab. doi:10.1007/s00403-023-02713-3 PubMed
- [6] Ghada F R Hassan et al.. J Cosmet Dermatol. 2022. Treatment with oral vitamin D alone, topical minoxidil, or combination of both in patients with female pattern hair loss: A … doi:10.1111/jocd.14743 PubMed
- [7] Marina de Queiroz et al.. J Cosmet Dermatol. 2022. Serum ferritin and vitamin D levels in women with non-scarring alopecia. doi:10.1111/jocd.14472 PubMed
- [8] Kriteeka Saini et al.. J Cosmet Dermatol. 2021. Role of vitamin D in hair loss: A short review. doi:10.1111/jocd.14421 PubMed
- [9] Sarita Sanke et al.. Int J Dermatol. 2020. Study of serum vitamin D levels in men with premature androgenetic alopecia. doi:10.1111/ijd.14982 PubMed
- [10] Jun Zhao et al.. J Cosmet Dermatol. 2020. Serum 25 hydroxyvitamin D levels in alopecia areata, female pattern hair loss, and male androgenetic alopecia in a Chinese population. doi:10.1111/jocd.13396 PubMed
- [11] Erika Titus-Lay et al.. Ment Health Clin. 2020. Trichotillomania associated with a 25-hydroxy vitamin D deficiency: A case report. doi:10.9740/mhc.2020.01.038 PubMed
- [12] Iman Seleit et al.. Indian J Dermatol. 2020. Vitamin D Receptor Gene Polymorphisms Taq-1 and Cdx-1 in Female Pattern Hair Loss. doi:10.4103/ijd.IJD_482_18 PubMed
- [13] Enrico Carmina et al.. J Clin Endocrinol Metab. 2019. Female Pattern Hair Loss and Androgen Excess: A Report From the Multidisciplinary Androgen Excess and PCOS Committee. doi:10.1210/jc.2018-02548 PubMed
- [14] Kavita Poonia et al.. J Cosmet Dermatol. 2019. NonScarring Diffuse Hair Loss in Women: a Clinico-Etiological Study from tertiary care center in North-West India. doi:10.1111/jocd.12559 PubMed
- [15] Silke Redler et al.. Exp Dermatol. 2017. Genetics and other factors in the aetiology of female pattern hair loss. doi:10.1111/exd.13373 PubMed
- [16] Agnieszka Gerkowicz et al.. Int J Mol Sci. 2017. The Role of Vitamin D in Non-Scarring Alopecia. doi:10.3390/ijms18122653 PubMed
- [17] Mahnaz Banihashemi et al.. Int J Trichology. 2016. Serum Vitamin D3 Level in Patients with Female Pattern Hair Loss. doi:10.4103/0974-7753.188965 PubMed
- [18] Tee Wei Siah et al.. Int J Trichology. 2016. Female Pattern Hair Loss: A Retrospective Study in a Tertiary Referral Center. doi:10.4103/0974-7753.188033 PubMed
- [19] H Rasheed et al.. Skin Pharmacol Physiol. 2013. Serum ferritin and vitamin d in female hair loss: do they play a role? doi:10.1159/000346698 PubMed
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