ビタミンD : 女性型脱毛症
A エビデンス 複数の大規模臨床試験が一貫して有意な効果を示しています。合計15,494名の参加者を対象とした18件の研究(メタアナリシス2件を含む)に基づく。研究間で結果にばらつきが見られる。
結論
Research shows that women with pattern hair loss often have lower vitamin D levels, but supplementing with vitamin D alone is unlikely to significantly improve this condition — it may be one supportive factor among many.
- Lower vitamin D levels are consistently found in women with pattern hair loss
- Supplementation alone is less effective than established options like minoxidil
- Vitamin D receptor gene variants may influence susceptibility
- Maintaining adequate vitamin D may support overall hair health but is not a standalone solution
Key Study Findings
対象集団: Women with non-scarring alopecia
Key Statistics
19
研究数
15494
参加者数
Mixed
グレード
Referenced Papers
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
一般的な使用量
- general:
- 600-800 IU/day
- deficiency:
- 1,000-5,000 IU/day
上限量: 4,000 IU/day
研究で検討された用量
| 用量 | 期間 | 効果 | N |
|---|---|---|---|
| None | -- | Positive | -- |
| None | -- | Negative | -- |
| None | -- | Neutral | 120 |
| not applicable (observational meta-analysis) | -- | Negative | 10670 |
| None | -- | Positive | 165 |
| None | -- | Mixed | -- |
| None | -- | Negative | -- |
| 1000 IU vitamin D3 daily | 16 weeks | Positive | 2 |
推奨摂取タイミング: With a fat-containing meal for optimal absorption
Safety & Side Effects
報告されている副作用
- ⚠ Hypercalcemia at very high doses (nausea, vomiting, weakness)
- ⚠ Kidney stones with excessive long-term use
- ⚠ Constipation
- ⚠ Metallic taste
既知の相互作用
- ● Thiazide diuretics (may increase risk of hypercalcemia)
- ● Corticosteroids (reduce vitamin D absorption and metabolism)
- ● Orlistat and cholestyramine (reduce fat-soluble vitamin absorption)
耐容上限摂取量: 4,000 IU/day
サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。
Frequently Asked Questions
Does ビタミンD help with 女性型脱毛症?
How much ビタミンD should I take for 女性型脱毛症?
Are there side effects of ビタミンD?
How strong is the evidence for ビタミンD and 女性型脱毛症?
Related Evidence
に関する他の成分: 女性型脱毛症
References
- [1] Adam Leavitt et al.. J Drugs Dermatol. 2025. Addressing the Root Causes of Female Hair Loss and Non-Pharmaceutical Interventions. doi:10.36849/JDD.8763 PubMed
- [2] Yuling Chen et al.. J Cosmet Dermatol. 2024. Serum 25 hydroxyvitamin D in non-scarring alopecia: A systematic review and meta-analysis. doi:10.1111/jocd.16093 PubMed
- [3] Tanat Yongpisarn et al.. Front Nutr. 2024. Vitamin D deficiency in non-scarring and scarring alopecias: a systematic review and meta-analysis. doi:10.3389/fnut.2024.1479337 PubMed
- [4] Palwasha Jalil et al.. Dermatol Pract Concept. 2024. Filling the Gaps: Vitamin D Status in Diffuse Hair Fall Among Pakistanis. doi:10.5826/dpc.1404a232 PubMed
- [5] Marissa S Ceresnie et al.. Arch Dermatol Res. 2023. The development of non-scarring alopecia in women who wear the hijab. doi:10.1007/s00403-023-02713-3 PubMed
- [6] Ghada F R Hassan et al.. J Cosmet Dermatol. 2022. Treatment with oral vitamin D alone, topical minoxidil, or combination of both in patients with female pattern hair loss: A … doi:10.1111/jocd.14743 PubMed
- [7] Marina de Queiroz et al.. J Cosmet Dermatol. 2022. Serum ferritin and vitamin D levels in women with non-scarring alopecia. doi:10.1111/jocd.14472 PubMed
- [8] Kriteeka Saini et al.. J Cosmet Dermatol. 2021. Role of vitamin D in hair loss: A short review. doi:10.1111/jocd.14421 PubMed
- [9] Sarita Sanke et al.. Int J Dermatol. 2020. Study of serum vitamin D levels in men with premature androgenetic alopecia. doi:10.1111/ijd.14982 PubMed
- [10] Jun Zhao et al.. J Cosmet Dermatol. 2020. Serum 25 hydroxyvitamin D levels in alopecia areata, female pattern hair loss, and male androgenetic alopecia in a Chinese population. doi:10.1111/jocd.13396 PubMed
- [11] Erika Titus-Lay et al.. Ment Health Clin. 2020. Trichotillomania associated with a 25-hydroxy vitamin D deficiency: A case report. doi:10.9740/mhc.2020.01.038 PubMed
- [12] Iman Seleit et al.. Indian J Dermatol. 2020. Vitamin D Receptor Gene Polymorphisms Taq-1 and Cdx-1 in Female Pattern Hair Loss. doi:10.4103/ijd.IJD_482_18 PubMed
- [13] Enrico Carmina et al.. J Clin Endocrinol Metab. 2019. Female Pattern Hair Loss and Androgen Excess: A Report From the Multidisciplinary Androgen Excess and PCOS Committee. doi:10.1210/jc.2018-02548 PubMed
- [14] Kavita Poonia et al.. J Cosmet Dermatol. 2019. NonScarring Diffuse Hair Loss in Women: a Clinico-Etiological Study from tertiary care center in North-West India. doi:10.1111/jocd.12559 PubMed
- [15] Silke Redler et al.. Exp Dermatol. 2017. Genetics and other factors in the aetiology of female pattern hair loss. doi:10.1111/exd.13373 PubMed
- [16] Agnieszka Gerkowicz et al.. Int J Mol Sci. 2017. The Role of Vitamin D in Non-Scarring Alopecia. doi:10.3390/ijms18122653 PubMed
- [17] Mahnaz Banihashemi et al.. Int J Trichology. 2016. Serum Vitamin D3 Level in Patients with Female Pattern Hair Loss. doi:10.4103/0974-7753.188965 PubMed
- [18] Tee Wei Siah et al.. Int J Trichology. 2016. Female Pattern Hair Loss: A Retrospective Study in a Tertiary Referral Center. doi:10.4103/0974-7753.188033 PubMed
- [19] H Rasheed et al.. Skin Pharmacol Physiol. 2013. Serum ferritin and vitamin d in female hair loss: do they play a role? doi:10.1159/000346698 PubMed
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