Selênio para Perda Capilar Relacionada à Tireoide
A Evidências Vários grandes ensaios clínicos mostram de forma consistente benefícios significativos.Baseado em 35 estudos (6 meta-analyses, 5 RCTs) com 10,466 participantes no total. Os resultados são variados entre os estudos.
Conclusão
Despite selenium's role in thyroid function, research does not support supplementing with selenium to improve thyroid-related hair loss, and excess selenium may actually worsen hair problems.
- Mixed results across 35 studies — no consistent benefit for hair loss
- Selenium is important for thyroid health, but supplementation has not shown hair benefits
- Selenium toxicity is a known cause of hair loss — excess intake is risky
- Consult a healthcare provider before supplementing, especially for thyroid concerns
Key Study Findings
População: Elderly participants aged 60+ from NHANES 2011-2014
População: Review of pharmacogenomics of THC and CBD
Key Statistics
38
Estudos
10748
Participantes
Mixed
Nota
Referenced Papers
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
Dosagens Comumente Utilizadas
- general:
- 55 mcg/day
Limite superior: 400 mcg/day
Dosagens Estudadas em Pesquisas
| Dosagem | Duração | Efeito | N |
|---|---|---|---|
| None | -- | Positive | 2582 |
| None | -- | Mixed | 7014 |
| None | -- | Neutral | 30 |
| None | -- | Mixed | -- |
| None | -- | Mixed | -- |
| None | -- | Positive | -- |
| NaSe 5.6ppm, Met 4.7ppm, DPDS 14.2ppm, NanoSe 2.7ppm | 4 weeks | Positive | 40 |
| not applicable | -- | Mixed | 180 |
Melhor horário: With meals for better absorption
Safety & Side Effects
Efeitos Colaterais Relatados
- ⚠ Hair loss at excessive doses (selenosis)
- ⚠ Brittle nails
- ⚠ Garlic-like breath odor at high doses
- ⚠ Nausea and diarrhea
Interações Conhecidas
- ● Statins (selenium may reduce statin effectiveness)
- ● Chemotherapy drugs (antioxidant effects may theoretically interfere)
- ● Niacin (may decrease HDL-raising effect when combined)
Ingestão máxima tolerável: 400 mcg/day
Consulte sempre o seu profissional de saúde antes de iniciar qualquer suplemento.Sempre consulte seu profissional de saúde antes de iniciar qualquer suplemento.
Frequently Asked Questions
Does Selênio help with Perda Capilar Relacionada à Tireoide?
How much Selênio should I take for Perda Capilar Relacionada à Tireoide?
Are there side effects of Selênio?
How strong is the evidence for Selênio and Perda Capilar Relacionada à Tireoide?
Related Evidence
Selênio para outras condições
References
- [1] Jiarui Miao et al.. Brain Behav. 2026. Relationship Between Serum Vitamins and Cognitive Impairment in the Elderly: A Study Based on the NHANES Database. doi:10.1002/brb3.71181 PubMed
- [2] A Mojadadi et al.. Redox Rep. 2025. Dietary supplementation of male mice with inorganic, organic or nanoparticle selenium preparations: evidence supporting a putative gut-thyroid-male fertility axis. doi:10.1080/13510002.2025.2495367 PubMed
- [3] Geir Bjørklund et al.. Curr Med Chem. 2025. Minerals and Trace Elements: Key Protectors of Skin Health and Defenders against Skin Disorders. doi:10.2174/0109298673348175250214054101 PubMed
- [4] Geir Bjørklund et al.. J Trace Elem Med Biol. 2025. The role of trace elements for the function and health of the skin. doi:10.1016/j.jtemb.2025.127674 PubMed
- [5] Deniz Duman Günsay et al.. Cutan Ocul Toxicol. 2025. Investigation of ischaemia-modified albumin and antioxidant vitamins and minerals levels in alopecia areata patients and evaluation of their relationship with … doi:10.1080/15569527.2025.2511723 PubMed
- [6] Małgorzata Kalak et al.. Genes (Basel). 2025. Medical Marijuana and Treatment Personalization: The Role of Genetics and Epigenetics in Response to THC and CBD. doi:10.3390/genes16121487 PubMed
- [7] Xinyi Shao et al.. Nutr Rev. 2025. Trace Elements and Risk of Immune-Mediated Skin Disease: A Systematic Review and Meta-analysis. doi:10.1093/nutrit/nuaf015 PubMed
- [8] Irem Nur Durusu Turkoglu et al.. J Cosmet Dermatol. 2024. A comprehensive investigation of biochemical status in patients with telogen effluvium: Analysis of Hb, ferritin, vitamin B12, vitamin D, thyroid … doi:10.1111/jocd.16512 PubMed
- [9] Ruilong Wang et al.. Mol Nutr Food Res. 2024. Micronutrients and Androgenetic Alopecia: A Systematic Review. doi:10.1002/mnfr.202400652 PubMed
- [10] Ekrem Civas et al.. J Cosmet Dermatol. 2024. Selenium in the supplement as the probable cause of hair loss and nail dystrophy. doi:10.1111/jocd.15902 PubMed
- [11] Winfried Häuser et al.. Cochrane Database Syst Rev. 2023. Cannabis-based medicines and medical cannabis for adults with cancer pain. doi:10.1002/14651858.CD014915.pub2 PubMed
- [12] Mary-Ann Fitzcharles et al.. Arthritis Care Res (Hoboken). 2023. Cautious Hope for Cannabidiol (CBD) in Rheumatology Care. doi:10.1002/acr.24176 PubMed
- [13] Moniek Schouten et al.. Front Pharmacol. 2023. Cannabidiol and brain function: current knowledge and future perspectives. doi:10.3389/fphar.2023.1328885 PubMed
- [14] Nathalie Y Ly et al.. J Am Acad Dermatol. 2023. Medical and procedural treatment of androgenetic alopecia - Where are we? doi:10.1016/j.jaad.2023.05.004 PubMed
- [15] Rakhtan K Qasba et al.. Medicina (Kaunas). 2023. Bartter Syndrome: A Systematic Review of Case Reports and Case Series. doi:10.3390/medicina59091638 PubMed
- [16] Michaela Bartončíková et al.. Molecules. 2023. Hemp-Derived CBD Used in Food and Food Supplements. doi:10.3390/molecules28248047 PubMed
- [17] Massimo Milani et al.. Skin Res Technol. 2023. Efficacy and tolerability of an oral supplement containing amino acids, iron, selenium, and marine hydrolyzed collagen in subjects with hair … doi:10.1111/srt.13381 PubMed
- [18] Paul T Kocis et al.. Med Cannabis Cannabinoids. 2023. CANNabinoid Drug Interaction Review (CANN-DIR™). doi:10.1159/000528528 PubMed
- [19] Róbert György Vida et al.. Front Pharmacol. 2023. Safety and risks of CBD oils purchased online: unveiling uncertain quality and vague health claims. doi:10.3389/fphar.2023.1273540 PubMed
- [20] Michela Starace et al.. Ital J Dermatol Venerol. 2023. Oral supplementation in female telogen effluvium: a clinical and instrumental objective evidence of efficacy and tolerability of new oral cosmetic … doi:10.23736/S2784-8671.22.07416-3 PubMed
- [21] Michael P St Blanc et al.. J Equine Vet Sci. 2022. Effects of a Supplement Containing Cannabidiol (CBD) on Sedation and Ataxia Scores and Health. doi:10.1016/j.jevs.2022.104085 PubMed
- [22] Edward Chesney et al.. Ther Adv Psychopharmacol. 2022. Acceptability of cannabidiol in patients with psychosis. doi:10.1177/20451253221128445 PubMed
- [23] Pellegrino Cerino et al.. Cannabis Cannabinoid Res. 2021. A Review of Hemp as Food and Nutritional Supplement. doi:10.1089/can.2020.0001 PubMed
- [24] Rahul Nachnani et al.. J Pharmacol Exp Ther. 2021. The Pharmacological Case for Cannabigerol. doi:10.1124/jpet.120.000340 PubMed
- [25] Thersilla Oberbarnscheidt et al.. J Clin Med Res. 2020. The Impact of Cannabidiol on Psychiatric and Medical Conditions. doi:10.14740/jocmr4159 PubMed
- [26] Paolo Daniele Pigatto et al.. Skin Appendage Disord. 2020. Alopecia Areata and Toxic Metals. doi:10.1159/000507296 PubMed
- [27] Arno Hazekamp. Med Cannabis Cannabinoids. 2018. The Trouble with CBD Oil. doi:10.1159/000489287 PubMed
- [28] Derrick D Brown. J Dance Med Sci. 2018. Nutritional Considerations for the Vegetarian and Vegan Dancer. doi:10.12678/1089-313X.22.1.44 PubMed
- [29] Jordan M Thompson et al.. Am J Clin Dermatol. 2017. The Role of Micronutrients in Alopecia Areata: A Review. doi:10.1007/s40257-017-0285-x PubMed
- [30] Waishu Jin et al.. J Dermatol. 2017. Changes of serum trace elements level in patients with alopecia areata: A meta-analysis. doi:10.1111/1346-8138.13705 PubMed
- [31] Jana Zímová et al.. Acta Dermatovenerol Croat. 2016. Trichotillomania: Bizzare Patern of Hair Loss at 11-Year-old Girl. PubMed
- [32] Amrita Khaire et al.. Prostaglandins Leukot Essent Fatty Acids. 2015. Vitamin B12 and omega-3 fatty acids together regulate lipid metabolism in Wistar rats. doi:10.1016/j.plefa.2015.04.006 PubMed
- [33] D Polivka et al.. Internist (Berl). 2015. [Vitamins and nutritional supplements in older persons: How to diagnose and when to substitute?]. doi:10.1007/s00108-015-3778-9 PubMed
- [34] Caroline Hwang et al.. Inflamm Bowel Dis. 2012. Micronutrient deficiencies in inflammatory bowel disease: from A to zinc. doi:10.1002/ibd.22906 PubMed
- [35] Dorota Szostak-Węgierek. Med Wieku Rozwoj. 2011. [Nutrition and fertility]. PubMed
- [36] Jack Metz. Food Nutr Bull. 2008. A high prevalence of biochemical evidence of vitamin B12 or folate deficiency does not translate into a comparable prevalence of … doi:10.1177/15648265080292S111 PubMed
- [37] Robert Clarke. N Engl J Med. 2006. Vitamin B12, folic acid, and the prevention of dementia. doi:10.1056/NEJMe068086 PubMed
- [38] Yao Sun et al.. Cardiovasc Res. 2006. Oxidative stress in aldosteronism. doi:10.1016/j.cardiores.2006.03.007 PubMed
- [39] H Mussalo-Rauhamaa et al.. Acta Derm Venereol. 1986. Element concentrations in serum, erythrocytes, hair and urine of alopecia patients. PubMed
Aviso Legal da FDA: Estas declarações não foram avaliadas pela Food and Drug Administration. Os produtos e informações neste site não se destinam a diagnosticar, tratar, curar ou prevenir qualquer doença. As notas de evidência apresentadas são baseadas em nossa análise de pesquisas revisadas por pares publicadas e não constituem aconselhamento médico. Sempre consulte seu profissional de saúde antes de iniciar qualquer regime de suplementação.