السيلينيوم لـ تساقط الشعر المرتبط بالغدة الدرقية
A الأدلة تُظهر تجارب سريرية كبيرة متعددة باستمرار فوائد ملحوظة.بناءً على 35 دراسة (6 meta-analyses, 5 RCTs) بمشاركة 10,466 مشاركًا إجمالاً. النتائج متباينة بين الدراسات.
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A
الخلاصة
Despite selenium's role in thyroid function, research does not support supplementing with selenium to improve thyroid-related hair loss, and excess selenium may actually worsen hair problems.
- Mixed results across 35 studies — no consistent benefit for hair loss
- Selenium is important for thyroid health, but supplementation has not shown hair benefits
- Selenium toxicity is a known cause of hair loss — excess intake is risky
- Consult a healthcare provider before supplementing, especially for thyroid concerns
Key Study Findings
Observational Study
n=2582
Relationship Between Serum Vitamins and Cognitive Impairment in the Elderly: A Study Based on the …
Dose: None
مقابل: None
Outcome: Cognitive impairment risk
التأثير: OR=0.695 (Vit D); OR=0.777 (FA)
p=0.003 (Vit D); p=0.034 (FA)
المجتمع المدروس: Elderly participants aged 60+ from NHANES 2011-2014
Systematic Review and Meta-Analysis
n=7014
Trace Elements and Risk of Immune-Mediated Skin Disease: A Systematic Review and Meta-analysis.
Dose: None
مقابل: Placebo
التأثير: Standardized mean differences reported for each element and disease combination (specific values not
None
prospective controlled study
n=30
Investigation of ischaemia-modified albumin and antioxidant vitamins and minerals levels in alopecia areata patients and …
Dose: None
مقابل: Placebo
التأثير: None
None
Review
The role of trace elements for the function and health of the skin.
Dose: None
مقابل: Placebo
التأثير: None
None
Review
Medical Marijuana and Treatment Personalization: The Role of Genetics and Epigenetics in Response to THC …
Dose: None
مقابل: None
Outcome: None
التأثير: None
None
المجتمع المدروس: Review of pharmacogenomics of THC and CBD
Review
Minerals and Trace Elements: Key Protectors of Skin Health and Defenders against Skin Disorders.
Dose: None
مقابل: Placebo
التأثير: None
None
Key Statistics
38
الدراسات
10748
المشاركون
↔
Mixed
A
التقييم
Referenced Papers
Brain and behavior
2026
Redox report : …
2025
8 اقتباسات
Minerals and Trace Elements: Key Protectors of Skin Health and Defenders against Skin Disorders.
Review
Current medicinal chemistry
2025
5 اقتباسات
Journal of trace …
2025
4 اقتباسات
Cutaneous and ocular …
2025
1 اقتباسات
Genes
2025
1 اقتباسات
Trace Elements and Risk of Immune-Mediated Skin Disease: A Systematic Review and Meta-analysis.
Meta-Analysis
Nutrition reviews
2025
Journal of cosmetic …
2024
7 اقتباسات
Micronutrients and Androgenetic Alopecia: A Systematic Review.
Systematic Review
Molecular nutrition & …
2024
7 اقتباسات
Journal of cosmetic …
2024
4 اقتباسات
The Cochrane database …
2023
47 اقتباسات
Arthritis care & …
2023
36 اقتباسات
Frontiers in pharmacology
2023
29 اقتباسات
Journal of the …
2023
20 اقتباسات
Bartter Syndrome: A Systematic Review of Case Reports and Case Series.
Systematic Review
Medicina (Kaunas, Lithuania)
2023
17 اقتباسات
Molecules (Basel, Switzerland)
2023
14 اقتباسات
Skin research and …
2023
11 اقتباسات
Medical cannabis and …
2023
9 اقتباسات
Safety and risks of CBD oils purchased online: unveiling uncertain quality and vague health claims.
Other
Frontiers in pharmacology
2023
8 اقتباسات
Italian journal of …
2023
3 اقتباسات
Journal of equine …
2022
6 اقتباسات
Therapeutic advances in …
2022
4 اقتباسات
Cannabis and cannabinoid …
2021
171 اقتباسات
The Journal of …
2021
162 اقتباسات
Journal of clinical …
2020
42 اقتباسات
Skin appendage disorders
2020
10 اقتباسات
Medical cannabis and …
2018
158 اقتباسات
Journal of dance …
2018
15 اقتباسات
American journal of …
2017
104 اقتباسات
Changes of serum trace elements level in patients with alopecia areata: A meta-analysis.
Meta-Analysis
The Journal of …
2017
31 اقتباسات
Acta dermatovenerologica Croatica …
2016
6 اقتباسات
Prostaglandins, leukotrienes, and …
2015
40 اقتباسات
[Vitamins and nutritional supplements in older persons: How to diagnose and when to substitute?].
Review
Der Internist
2015
3 اقتباسات
Inflammatory bowel diseases
2012
224 اقتباسات
Medycyna wieku rozwojowego
2011
Food and nutrition …
2008
83 اقتباسات
The New England …
2006
47 اقتباسات
Cardiovascular research
2006
42 اقتباسات
Acta dermato-venereologica
1986
53 اقتباسات
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
الجرعات الشائعة
- general:
- 55 mcg/day
الحد الأعلى: 400 mcg/day
الجرعات المدروسة في الأبحاث
| الجرعة | المدة | التأثير | ن |
|---|---|---|---|
| None | -- | Positive | 2582 |
| None | -- | Mixed | 7014 |
| None | -- | Neutral | 30 |
| None | -- | Mixed | -- |
| None | -- | Mixed | -- |
| None | -- | Positive | -- |
| NaSe 5.6ppm, Met 4.7ppm, DPDS 14.2ppm, NanoSe 2.7ppm | 4 weeks | Positive | 40 |
| not applicable | -- | Mixed | 180 |
أفضل وقت للتناول: With meals for better absorption
Safety & Side Effects
الآثار الجانبية المُبلّغ عنها
- ⚠ Hair loss at excessive doses (selenosis)
- ⚠ Brittle nails
- ⚠ Garlic-like breath odor at high doses
- ⚠ Nausea and diarrhea
التفاعلات المعروفة
- ● Statins (selenium may reduce statin effectiveness)
- ● Chemotherapy drugs (antioxidant effects may theoretically interfere)
- ● Niacin (may decrease HDL-raising effect when combined)
الحد الأقصى المسموح به: 400 mcg/day
استشر مقدم الرعاية الصحية دائماً قبل البدء بأي مكمل غذائي.
Frequently Asked Questions
Does السيلينيوم help with تساقط الشعر المرتبط بالغدة الدرقية?
Based on 38 studies with 10,748 participants, there is strong evidence from multiple clinical trials that السيلينيوم may support تساقط الشعر المرتبط بالغدة الدرقية management. Our evidence grade is A (Strong Evidence).
How much السيلينيوم should I take for تساقط الشعر المرتبط بالغدة الدرقية?
Studies have used various dosages. A commonly studied range is 55 mcg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of السيلينيوم?
Reported side effects may include Hair loss at excessive doses (selenosis), Brittle nails, Garlic-like breath odor at high doses, Nausea and diarrhea. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for السيلينيوم and تساقط الشعر المرتبط بالغدة الدرقية?
We rate the evidence as Grade A (Strong Evidence). This rating is based on 38 peer-reviewed studies with 10,748 total participants. The overall direction of effect is mixed.
Related Evidence
السيلينيوم لحالات أخرى
References
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إخلاء مسؤولية FDA: لم تُقيَّم هذه البيانات من قبل إدارة الغذاء والدواء (FDA). لا تهدف المنتجات والمعلومات الواردة في هذا الموقع إلى تشخيص أو علاج أو شفاء أو الوقاية من أي مرض. تستند تقييمات الأدلة المعروضة إلى تحليلنا للأبحاث المحكّمة المنشورة ولا تُشكّل نصيحة طبية. استشر مقدم الرعاية الصحية دائماً قبل البدء بأي نظام مكملات.