Селен для Выпадение волос, связанное с щитовидной железой
A Доказательства Несколько крупных клинических испытаний стабильно демонстрируют значительные преимущества.На основе 35 исследований (6 meta-analyses, 5 RCTs) с участием 10,466 участников. Результаты исследований неоднозначны.
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A
Итог
Despite selenium's role in thyroid function, research does not support supplementing with selenium to improve thyroid-related hair loss, and excess selenium may actually worsen hair problems.
- Mixed results across 35 studies — no consistent benefit for hair loss
- Selenium is important for thyroid health, but supplementation has not shown hair benefits
- Selenium toxicity is a known cause of hair loss — excess intake is risky
- Consult a healthcare provider before supplementing, especially for thyroid concerns
Key Study Findings
Observational Study
n=2582
Relationship Between Serum Vitamins and Cognitive Impairment in the Elderly: A Study Based on the …
Dose: None
или: None
Outcome: Cognitive impairment risk
Эффект: OR=0.695 (Vit D); OR=0.777 (FA)
p=0.003 (Vit D); p=0.034 (FA)
Популяция: Elderly participants aged 60+ from NHANES 2011-2014
Systematic Review and Meta-Analysis
n=7014
Trace Elements and Risk of Immune-Mediated Skin Disease: A Systematic Review and Meta-analysis.
Dose: None
или: Placebo
Эффект: Standardized mean differences reported for each element and disease combination (specific values not
None
prospective controlled study
n=30
Investigation of ischaemia-modified albumin and antioxidant vitamins and minerals levels in alopecia areata patients and …
Dose: None
или: Placebo
Эффект: None
None
Review
The role of trace elements for the function and health of the skin.
Dose: None
или: Placebo
Эффект: None
None
Review
Medical Marijuana and Treatment Personalization: The Role of Genetics and Epigenetics in Response to THC …
Dose: None
или: None
Outcome: None
Эффект: None
None
Популяция: Review of pharmacogenomics of THC and CBD
Review
Minerals and Trace Elements: Key Protectors of Skin Health and Defenders against Skin Disorders.
Dose: None
или: Placebo
Эффект: None
None
Key Statistics
38
Исследования
10748
Участники
↔
Mixed
A
Оценка
Referenced Papers
Brain and behavior
2026
Redox report : …
2025
8 цитирований
Minerals and Trace Elements: Key Protectors of Skin Health and Defenders against Skin Disorders.
Review
Current medicinal chemistry
2025
5 цитирований
Journal of trace …
2025
4 цитирований
Cutaneous and ocular …
2025
1 цитирований
Genes
2025
1 цитирований
Trace Elements and Risk of Immune-Mediated Skin Disease: A Systematic Review and Meta-analysis.
Meta-Analysis
Nutrition reviews
2025
Journal of cosmetic …
2024
7 цитирований
Micronutrients and Androgenetic Alopecia: A Systematic Review.
Systematic Review
Molecular nutrition & …
2024
7 цитирований
Journal of cosmetic …
2024
4 цитирований
The Cochrane database …
2023
47 цитирований
Arthritis care & …
2023
36 цитирований
Frontiers in pharmacology
2023
29 цитирований
Journal of the …
2023
20 цитирований
Bartter Syndrome: A Systematic Review of Case Reports and Case Series.
Systematic Review
Medicina (Kaunas, Lithuania)
2023
17 цитирований
Molecules (Basel, Switzerland)
2023
14 цитирований
Skin research and …
2023
11 цитирований
Medical cannabis and …
2023
9 цитирований
Safety and risks of CBD oils purchased online: unveiling uncertain quality and vague health claims.
Other
Frontiers in pharmacology
2023
8 цитирований
Italian journal of …
2023
3 цитирований
Journal of equine …
2022
6 цитирований
Therapeutic advances in …
2022
4 цитирований
Cannabis and cannabinoid …
2021
171 цитирований
The Journal of …
2021
162 цитирований
Journal of clinical …
2020
42 цитирований
Skin appendage disorders
2020
10 цитирований
Medical cannabis and …
2018
158 цитирований
Journal of dance …
2018
15 цитирований
American journal of …
2017
104 цитирований
Changes of serum trace elements level in patients with alopecia areata: A meta-analysis.
Meta-Analysis
The Journal of …
2017
31 цитирований
Acta dermatovenerologica Croatica …
2016
6 цитирований
Prostaglandins, leukotrienes, and …
2015
40 цитирований
[Vitamins and nutritional supplements in older persons: How to diagnose and when to substitute?].
Review
Der Internist
2015
3 цитирований
Inflammatory bowel diseases
2012
224 цитирований
Medycyna wieku rozwojowego
2011
Food and nutrition …
2008
83 цитирований
The New England …
2006
47 цитирований
Cardiovascular research
2006
42 цитирований
Acta dermato-venereologica
1986
53 цитирований
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
Часто используемые дозировки
- general:
- 55 mcg/day
Верхний предел: 400 mcg/day
Дозировки, изученные в исследованиях
| Дозировка | Длительность | Эффект | N |
|---|---|---|---|
| None | -- | Positive | 2582 |
| None | -- | Mixed | 7014 |
| None | -- | Neutral | 30 |
| None | -- | Mixed | -- |
| None | -- | Mixed | -- |
| None | -- | Positive | -- |
| NaSe 5.6ppm, Met 4.7ppm, DPDS 14.2ppm, NanoSe 2.7ppm | 4 weeks | Positive | 40 |
| not applicable | -- | Mixed | 180 |
Лучшее время приёма: With meals for better absorption
Safety & Side Effects
Зарегистрированные побочные эффекты
- ⚠ Hair loss at excessive doses (selenosis)
- ⚠ Brittle nails
- ⚠ Garlic-like breath odor at high doses
- ⚠ Nausea and diarrhea
Известные взаимодействия
- ● Statins (selenium may reduce statin effectiveness)
- ● Chemotherapy drugs (antioxidant effects may theoretically interfere)
- ● Niacin (may decrease HDL-raising effect when combined)
Допустимый верхний уровень потребления: 400 mcg/day
Всегда консультируйтесь с врачом перед началом приёма любых добавок.Всегда консультируйтесь с лечащим врачом перед началом приёма любой добавки.
Frequently Asked Questions
Does Селен help with Выпадение волос, связанное с щитовидной железой?
Based on 38 studies with 10,748 participants, there is strong evidence from multiple clinical trials that Селен may support Выпадение волос, связанное с щитовидной железой management. Our evidence grade is A (Strong Evidence).
How much Селен should I take for Выпадение волос, связанное с щитовидной железой?
Studies have used various dosages. A commonly studied range is 55 mcg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Селен?
Reported side effects may include Hair loss at excessive doses (selenosis), Brittle nails, Garlic-like breath odor at high doses, Nausea and diarrhea. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Селен and Выпадение волос, связанное с щитовидной железой?
We rate the evidence as Grade A (Strong Evidence). This rating is based on 38 peer-reviewed studies with 10,748 total participants. The overall direction of effect is mixed.
Related Evidence
Селен для других состояний
References
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