Selênio para Perda Capilar por Deficiência Nutricional

Baseado em 35 estudos (6 meta-analyses, 5 RCTs) com 10,466 participantes no total. Os resultados são variados entre os estudos.

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Conclusão

Research does not support selenium supplementation for hair loss — in fact, excessive selenium intake has been associated with hair loss, so supplementation without a confirmed deficiency is not recommended.

Mixed results across 35 studies — no clear benefit for hair loss
Both selenium deficiency and excess may contribute to hair problems
Case reports have linked selenium supplements to hair loss and nail damage
Only supplement if a healthcare provider has confirmed a deficiency

Key Study Findings

Observational Study n=2582

Relationship Between Serum Vitamins and Cognitive Impairment in the Elderly: A Study Based on the …

Dose: None vs: None Outcome: Cognitive impairment risk Efeito: OR=0.695 (Vit D); OR=0.777 (FA) p=0.003 (Vit D); p=0.034 (FA)

População: Elderly participants aged 60+ from NHANES 2011-2014

Systematic Review and Meta-Analysis n=7014

Trace Elements and Risk of Immune-Mediated Skin Disease: A Systematic Review and Meta-analysis.

Dose: None vs: Placebo Efeito: Standardized mean differences reported for each element and disease combination (specific values not None

prospective controlled study n=30

Investigation of ischaemia-modified albumin and antioxidant vitamins and minerals levels in alopecia areata patients and …

Dose: None vs: Placebo Efeito: None None

Review

The role of trace elements for the function and health of the skin.

Dose: None vs: Placebo Efeito: None None

Review

Medical Marijuana and Treatment Personalization: The Role of Genetics and Epigenetics in Response to THC …

Dose: None vs: None Outcome: None Efeito: None None

População: Review of pharmacogenomics of THC and CBD

Review

Minerals and Trace Elements: Key Protectors of Skin Health and Defenders against Skin Disorders.

Dose: None vs: Placebo Efeito: None None

Key Statistics

Estudos

10748

Participantes

↔

Mixed

Nota

Referenced Papers

Relationship Between Serum Vitamins and Cognitive Impairment in the Elderly: A Study Based on the NHANES Database. Other

Brain and behavior 2026

Dietary supplementation of male mice with inorganic, organic or nanoparticle selenium preparations: evidence supporting a putative gut-thyroid-male fertility axis. Other

Redox report : … 2025 8 citações

Minerals and Trace Elements: Key Protectors of Skin Health and Defenders against Skin Disorders. Review

Current medicinal chemistry 2025 5 citações

The role of trace elements for the function and health of the skin. Review

Journal of trace … 2025 4 citações

Investigation of ischaemia-modified albumin and antioxidant vitamins and minerals levels in alopecia areata patients and evaluation of their relationship with … Other

Cutaneous and ocular … 2025 1 citações

Medical Marijuana and Treatment Personalization: The Role of Genetics and Epigenetics in Response to THC and CBD. Review

Genes 2025 1 citações

Trace Elements and Risk of Immune-Mediated Skin Disease: A Systematic Review and Meta-analysis. Meta-Analysis

Nutrition reviews 2025

A comprehensive investigation of biochemical status in patients with telogen effluvium: Analysis of Hb, ferritin, vitamin B12, vitamin D, thyroid … Other

Journal of cosmetic … 2024 7 citações

Micronutrients and Androgenetic Alopecia: A Systematic Review. Systematic Review

Molecular nutrition & … 2024 7 citações

Selenium in the supplement as the probable cause of hair loss and nail dystrophy. Other

Journal of cosmetic … 2024 4 citações

Cannabis-based medicines and medical cannabis for adults with cancer pain. Meta-Analysis

The Cochrane database … 2023 47 citações

Cautious Hope for Cannabidiol (CBD) in Rheumatology Care. Review

Arthritis care & … 2023 36 citações

Cannabidiol and brain function: current knowledge and future perspectives. Review

Frontiers in pharmacology 2023 29 citações

Medical and procedural treatment of androgenetic alopecia - Where are we? Review

Journal of the … 2023 20 citações

Bartter Syndrome: A Systematic Review of Case Reports and Case Series. Systematic Review

Medicina (Kaunas, Lithuania) 2023 17 citações

Hemp-Derived CBD Used in Food and Food Supplements. Review

Molecules (Basel, Switzerland) 2023 14 citações

Efficacy and tolerability of an oral supplement containing amino acids, iron, selenium, and marine hydrolyzed collagen in subjects with hair … RCT

Skin research and … 2023 11 citações

CANNabinoid Drug Interaction Review (CANN-DIR™). Review

Medical cannabis and … 2023 9 citações

Safety and risks of CBD oils purchased online: unveiling uncertain quality and vague health claims. Other

Frontiers in pharmacology 2023 8 citações

Oral supplementation in female telogen effluvium: a clinical and instrumental objective evidence of efficacy and tolerability of new oral cosmetic … Other

Italian journal of … 2023 3 citações

Effects of a Supplement Containing Cannabidiol (CBD) on Sedation and Ataxia Scores and Health. RCT

Journal of equine … 2022 6 citações

Acceptability of cannabidiol in patients with psychosis. Other

Therapeutic advances in … 2022 4 citações

A Review of Hemp as Food and Nutritional Supplement. Review

Cannabis and cannabinoid … 2021 171 citações

The Pharmacological Case for Cannabigerol. Review

The Journal of … 2021 162 citações

The Impact of Cannabidiol on Psychiatric and Medical Conditions. Review

Journal of clinical … 2020 42 citações

Alopecia Areata and Toxic Metals. Other

Skin appendage disorders 2020 10 citações

The Trouble with CBD Oil. Other

Medical cannabis and … 2018 158 citações

Nutritional Considerations for the Vegetarian and Vegan Dancer. Review

Journal of dance … 2018 15 citações

The Role of Micronutrients in Alopecia Areata: A Review. Review

American journal of … 2017 104 citações

Changes of serum trace elements level in patients with alopecia areata: A meta-analysis. Meta-Analysis

The Journal of … 2017 31 citações

Trichotillomania: Bizzare Patern of Hair Loss at 11-Year-old Girl. Case Report

Acta dermatovenerologica Croatica … 2016 6 citações

Vitamin B12 and omega-3 fatty acids together regulate lipid metabolism in Wistar rats. Other

Prostaglandins, leukotrienes, and … 2015 40 citações

[Vitamins and nutritional supplements in older persons: How to diagnose and when to substitute?]. Review

Der Internist 2015 3 citações

Micronutrient deficiencies in inflammatory bowel disease: from A to zinc. Review

Inflammatory bowel diseases 2012 224 citações

[Nutrition and fertility]. Other

Medycyna wieku rozwojowego 2011

A high prevalence of biochemical evidence of vitamin B12 or folate deficiency does not translate into a comparable prevalence of … Review

Food and nutrition … 2008 83 citações

Vitamin B12, folic acid, and the prevention of dementia. Other

The New England … 2006 47 citações

Oxidative stress in aldosteronism. Review

Cardiovascular research 2006 42 citações

Element concentrations in serum, erythrocytes, hair and urine of alopecia patients. Other

Acta dermato-venereologica 1986 53 citações

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Dosagens Comumente Utilizadas

general:: 55 mcg/day

Limite superior: 400 mcg/day

Dosagens Estudadas em Pesquisas

Dosagem	Duração	Efeito	N
None	--	Positive	2582
None	--	Mixed	7014
None	--	Neutral	30
None	--	Mixed	--
None	--	Mixed	--
None	--	Positive	--
NaSe 5.6ppm, Met 4.7ppm, DPDS 14.2ppm, NanoSe 2.7ppm	4 weeks	Positive	40
not applicable	--	Mixed	180

Melhor horário: With meals for better absorption

Safety & Side Effects

Efeitos Colaterais Relatados

⚠ Hair loss at excessive doses (selenosis)
⚠ Brittle nails
⚠ Garlic-like breath odor at high doses
⚠ Nausea and diarrhea

Interações Conhecidas

● Statins (selenium may reduce statin effectiveness)
● Chemotherapy drugs (antioxidant effects may theoretically interfere)
● Niacin (may decrease HDL-raising effect when combined)

Ingestão máxima tolerável: 400 mcg/day

Consulte sempre o seu profissional de saúde antes de iniciar qualquer suplemento.Sempre consulte seu profissional de saúde antes de iniciar qualquer suplemento.

Frequently Asked Questions

Does Selênio help with Perda Capilar por Deficiência Nutricional?

Based on 38 studies with 10,748 participants, there is strong evidence from multiple clinical trials that Selênio may support Perda Capilar por Deficiência Nutricional management. Our evidence grade is A (Strong Evidence).

How much Selênio should I take for Perda Capilar por Deficiência Nutricional?

Studies have used various dosages. A commonly studied range is 55 mcg/day. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Selênio?

Reported side effects may include Hair loss at excessive doses (selenosis), Brittle nails, Garlic-like breath odor at high doses, Nausea and diarrhea. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Selênio and Perda Capilar por Deficiência Nutricional?

We rate the evidence as Grade A (Strong Evidence). This rating is based on 38 peer-reviewed studies with 10,748 total participants. The overall direction of effect is mixed.

Related Evidence

Outros ingredientes para Perda Capilar por Deficiência Nutricional

Biotin B Vitamin A D L-Cisteína D Vitamina B12 F Folato F

Selênio para outras condições

Perda Capilar Relacionada à Tireoide A

Veredito Rápido

Baseado em 35 estudos (6 meta-analyses, 5 RCTs) com 10,466 participantes no total. Os resultados são variados entre os estudos.

Evidence Strength92%

High confidence

Detalhamento dos Estudos

RCT (2)Meta (3)Other (33)

Comparar Alternativas

Veja como outros ingredientes se comparam para esta condição.

Ver todos os ingredientes para Perda Capilar por Deficiência Nutricional

Saiba Mais

Aviso Legal da FDA: Estas declarações não foram avaliadas pela Food and Drug Administration. Os produtos e informações neste site não se destinam a diagnosticar, tratar, curar ou prevenir qualquer doença. As notas de evidência apresentadas são baseadas em nossa análise de pesquisas revisadas por pares publicadas e não constituem aconselhamento médico. Sempre consulte seu profissional de saúde antes de iniciar qualquer regime de suplementação.