Óleo de semente de abóbora para Alopecia Androgenética
ABaseado em 14 estudos (2 meta-analyses, 3 RCTs) com 1,874 participantes no total. 13/14 estudos mostram efeitos positivos.
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A
Conclusão
Pumpkin seed oil is well-supported by multiple clinical trials as a natural supplement that may help promote hair growth in androgenetic alopecia through its DHT-blocking properties.
- 13 out of 14 studies show positive effects, including 3 RCTs
- Acts as a natural 5-alpha reductase inhibitor, potentially reducing DHT levels
- Both oral supplementation and topical application have been studied
- One RCT showed comparable results to minoxidil 5% in women
Key Study Findings
narrative review
Addressing the Root Causes of Female Hair Loss and Non-Pharmaceutical Interventions.
Dose: None
vs: Placebo
Efeito: None
None
RCT
n=80
24 weeks
Double-blind
Oral Supplementation with l-Cystine, Serenoa repens, Cucurbita pepo, and Pygeum africanum in Chronic Telogen Effluvium …
Dose: 1 capsule daily (l-Cystine, Serenoa repens, Cucurbita pepo, Pygeum africanum, vitamins, micronutrien
vs: Placebo
Efeito: MD=+12.3 hairs/cm2 at 6 months
p<0.05
narrative review
Herbal Remedies for Hair Loss: A Review of Efficacy and Safety.
Dose: varies by remedy and study
vs: Placebo
Efeito: None
None
systematic review
n=1658
Double-blind
Effects of dietary supplements on androgenetic alopecia: a systematic review and network meta-analysis.
Dose: various dietary supplements (Nutrafol, apple extract, tocotrienols, pumpkin seed oil, Cistanche/Lami
vs: Placebo
Efeito: None
None
review
Single-blind
Do Non-Prescription Products Help in Managing Androgenic Alopecia?
Dose: Various non-prescription agents: procyanidin, cetirizine, caffeine, Oryza sativa bran, pumpkin seed
vs: Placebo
Efeito: Considerable improvements in one or more parameters across 13 included studies
None
review
Emerging and traditional 5-α reductase inhibitors and androgen receptor antagonists for male androgenetic alopecia.
Dose: finasteride 1 mg/day; dutasteride 0.5 mg/day; various natural product doses
vs: Placebo
Efeito: None
None
Key Statistics
15
Estudos
1874
Participantes
↑
Positive
A
Nota
Referenced Papers
Skin appendage disorders
2025
7 citações
Skin appendage disorders
2025
3 citações
Skin appendage disorders
2025
1 citações
Journal of drugs …
2025
Effects of dietary supplements on androgenetic alopecia: a systematic review and network meta-analysis.
Systematic Review
Frontiers in nutrition
2025
Proceedings (Baylor University. …
2024
14 citações
Expert opinion on …
2024
8 citações
Clinical, cosmetic and …
2024
7 citações
Dermatologic therapy
2022
41 citações
Journal of cosmetic …
2021
29 citações
Archives of dermatological …
2020
51 citações
The Journal of …
2020
24 citações
Journal of cosmetic …
2019
100 citações
Beneficial effects of pumpkin seed oil as a topical hair growth promoting agent in a mice model.
Other
Avicenna journal of …
2019
23 citações
Evidence-based complementary and …
2015
4 citações
Evidence-based complementary and …
2014
86 citações
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
Dosagens Comumente Utilizadas
- hairloss:
- 400 mg/day
Limite superior: Not established
Dosagens Estudadas em Pesquisas
| Dosagem | Duração | Efeito | N |
|---|---|---|---|
| None | -- | Positive | -- |
| 1 capsule daily (l-Cystine, Serenoa repens, Cucurbita pepo, Pygeum africanum, vitamins, micronutrien | 24 weeks | Positive | 80 |
| varies by remedy and study | -- | Positive | -- |
| various dietary supplements (Nutrafol, apple extract, tocotrienols, pumpkin seed oil, Cistanche/Lami | -- | Positive | 1658 |
| Various non-prescription agents: procyanidin, cetirizine, caffeine, Oryza sativa bran, pumpkin seed | -- | Positive | -- |
| finasteride 1 mg/day; dutasteride 0.5 mg/day; various natural product doses | -- | Positive | -- |
| various CAMs: pumpkin seed oil, saw palmetto, melatonin extract, caffeine extract, rosemary oil | -- | Positive | -- |
| not specified | -- | Positive | -- |
Melhor horário: With meals for better absorption
Safety & Side Effects
Efeitos Colaterais Relatados
- ⚠ Mild gastrointestinal upset
- ⚠ Possible stomach discomfort at high doses
- ⚠ Rare allergic reactions in individuals with cucurbit allergies
Interações Conhecidas
- ● Anticoagulants (theoretical increased bleeding risk)
- ● Lithium (pumpkin seed oil may have diuretic properties)
Ingestão máxima tolerável: Not established
Consulte sempre o seu profissional de saúde antes de iniciar qualquer suplemento.Sempre consulte seu profissional de saúde antes de iniciar qualquer suplemento.
Frequently Asked Questions
Does Óleo de semente de abóbora help with Alopecia Androgenética?
Based on 15 studies with 1,874 participants, there is strong evidence from multiple clinical trials that Óleo de semente de abóbora may support Alopecia Androgenética management. Our evidence grade is A (Strong Evidence).
How much Óleo de semente de abóbora should I take for Alopecia Androgenética?
Studies have used various dosages. A commonly studied range is 400 mg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Óleo de semente de abóbora?
Reported side effects may include Mild gastrointestinal upset, Possible stomach discomfort at high doses, Rare allergic reactions in individuals with cucurbit allergies. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Óleo de semente de abóbora and Alopecia Androgenética?
We rate the evidence as Grade A (Strong Evidence). This rating is based on 15 peer-reviewed studies with 1,874 total participants. The overall direction of effect is positive.
Related Evidence
Outros ingredientes para Alopecia Androgenética
Aviso Legal da FDA: Estas declarações não foram avaliadas pela Food and Drug Administration. Os produtos e informações neste site não se destinam a diagnosticar, tratar, curar ou prevenir qualquer doença. As notas de evidência apresentadas são baseadas em nossa análise de pesquisas revisadas por pares publicadas e não constituem aconselhamento médico. Sempre consulte seu profissional de saúde antes de iniciar qualquer regime de suplementação.