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Terapia PRP para Alopecia Androgenética

A

Baseado em 57 estudos (13 meta-analyses, 6 RCTs) com 6,423 participantes no total. 51/57 estudos mostram efeitos positivos.

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A

Conclusão

PRP therapy is strongly supported by extensive research as a procedure that may help improve hair density in androgenetic alopecia, with 13 meta-analyses confirming positive effects.

  • 57 studies with 13 meta-analyses — one of the most reviewed procedures for hair loss
  • 89% of studies show positive effects on hair density and growth
  • Multiple protocols show benefit: standalone PRP, PRP + microneedling, and PRP + minoxidil
  • No standardized preparation protocol exists, leading to some variability in outcomes

Key Study Findings

Randomized Controlled Trial n=27 12 weeks Single-blind
Platelet-Rich Plasma Treatment for Endocrine-Induced Alopecia and Persistent Chemotherapy-Induced Alopecia in Breast Cancer Survivors: A …
Dose: Monthly for 3 months vs: Untreated side of scalp (split-scalp) Outcome: Global assessment scale change at week 12 Efeito: +1.2 GAS; +21 hairs/cm2 treated vs +16 untreated p < 0.001 (GAS); p > 0.05 (bet

População: Breast cancer survivors with EIA or pCIA

Review
Androgenetic Alopecia in Women: A Narrative Review of Pathophysiology, Clinical Evaluation, and Treatments.
Dose: None vs: None Outcome: None Efeito: None None

População: women with androgenetic alopecia (female pattern hair loss)

Systematic Review
Relative efficacy of minoxidil in combination with other treatments for androgenic alopecia: a network meta-analysis …
Dose: None vs: Minoxidil alone; Bayesian NMA of 20 study groups Outcome: Hair density change (SUCRA ranking) Efeito: PRP+bFGF+minox SUCRA=93.06%; +35.12 hairs/cm² None

População: Patients with AGA (network meta-analysis of RCTs)

Review
Promises and Pitfalls of Regenerative Therapies for Androgenetic Alopecia: Platelet-Rich Plasma, Photobiomodulation, Stem Cells, and …
Dose: None vs: None Outcome: None Efeito: None None

População: Review of regenerative therapies for AGA (2020-2025)

Randomized Controlled Trial n=30
A Prospective and Comparative Study to Explore the Effects of Platelet-Rich Plasma in Hair Transplantation …
Dose: None vs: Drug therapy (minoxidil + finasteride/spironolactone) only Outcome: Follicle survival rate, growth rate, hair strength Efeito: None None

População: Patients with androgenetic alopecia

Controlled Clinical Trial n=41 12 weeks Open-label
Effectiveness of Autologous Platelet-Rich Plasma for Androgenetic Alopecia: A Double-Center, Non-Controlled, Randomized Clinical Study in …
Dose: 3 sessions at 4-week intervals vs: Pre-treatment baseline (single-arm) Outcome: Hair density change Efeito: 40.76 to 66.00 hairs/cm2 <0.05

População: Vietnamese patients with androgenetic alopecia

Key Statistics

144

Estudos

8892

Participantes

Positive

A

Nota

Referenced Papers

Journal of cutaneous … 2025 2 citações
Annals of dermatology 2025
International journal of … 2024 39 citações
Journal of cosmetic … 2024 12 citações
Journal of cosmetic … 2024 11 citações
Facial plastic surgery … 2024 8 citações
Revue medicale suisse 2024 2 citações
Clinical, cosmetic and … 2023 58 citações
American journal of … 2023 41 citações
International journal of … 2023 5 citações
Clinics in plastic … 2023 1 citações
Drug design, development … 2022 70 citações
Faculty reviews 2022 44 citações
Dermatology and therapy 2022 43 citações
Journal of cosmetic … 2022 35 citações
The journal of … 2022 22 citações
Dermatologic surgery : … 2022 15 citações
Skinmed 2022 3 citações
American family physician 2022 2 citações
Facial plastic surgery … 2022
Journal of cosmetic … 2021 23 citações
Indian dermatology online … 2021 17 citações
The Senior care … 2021 2 citações
Expert opinion on … 2020 147 citações
Facial plastic surgery … 2020 36 citações
Indian dermatology online … 2020 33 citações
Dermatologic surgery : … 2020 32 citações
Journal of drugs … 2020 11 citações
Dermatologic surgery : … 2019 68 citações
Aesthetic plastic surgery 2019 45 citações
Journal of cosmetic … 2019 30 citações
Dermatologic therapy 2019 14 citações
Indian journal of … 2019 10 citações
Skinmed 2019 7 citações
Dermatologic clinics 2019 7 citações
International journal of … 2018 129 citações
Journal of the … 2018 114 citações
Facial plastic surgery … 2018 43 citações
International journal of … 2018 42 citações
Facial plastic surgery … 2018 42 citações
Journal of stomatology, … 2017 30 citações
Stem cell investigation 2017 27 citações
International journal of … 2015 79 citações
Journal of cutaneous … 2014 168 citações
Dermatologic surgery : … 2014 140 citações
Expert opinion on … 2014 57 citações
Journal of nutrition … 2008 32 citações

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Dosagens Comumente Utilizadas

hairloss:
3-4 sessions, 4-6 weeks apart

Limite superior: Not applicable

Dosagens Estudadas em Pesquisas

Dosagem Duração Efeito N
Monthly for 3 months 12 weeks Neutral 27
None -- Neutral --
None -- Positive --
None -- Mixed --
None -- Positive 30
3 sessions at 4-week intervals 12 weeks Positive 41
Oral minoxidil (low-dose); topical minoxidil 5% 32 weeks Positive 75
3 monthly PRP sessions 24 weeks Neutral 20

Melhor horário: In-clinic procedure; avoid washing hair for 24 hours after treatment

Safety & Side Effects

Efeitos Colaterais Relatados

  • Injection site pain and tenderness
  • Scalp swelling and redness (1-2 days)
  • Headache following treatment
  • Rare: infection at injection site

Interações Conhecidas

  • NSAIDs and aspirin (discontinue 1 week before PRP; affect platelet function)
  • Anticoagulants (may increase bruising; consult physician)
  • Corticosteroid injections (may reduce PRP effectiveness)

Ingestão máxima tolerável: Not applicable

Consulte sempre o seu profissional de saúde antes de iniciar qualquer suplemento.Sempre consulte seu profissional de saúde antes de iniciar qualquer suplemento.

Frequently Asked Questions

Does Terapia PRP help with Alopecia Androgenética?
Based on 144 studies with 8,892 participants, there is strong evidence from multiple clinical trials that Terapia PRP may support Alopecia Androgenética management. Our evidence grade is A (Strong Evidence).
How much Terapia PRP should I take for Alopecia Androgenética?
Studies have used various dosages. A commonly studied range is 3-4 sessions, 4-6 weeks apart. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Terapia PRP?
Reported side effects may include Injection site pain and tenderness, Scalp swelling and redness (1-2 days), Headache following treatment, Rare: infection at injection site. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Terapia PRP and Alopecia Androgenética?
We rate the evidence as Grade A (Strong Evidence). This rating is based on 144 peer-reviewed studies with 8,892 total participants. The overall direction of effect is positive.

Related Evidence

Aviso Legal da FDA: Estas declarações não foram avaliadas pela Food and Drug Administration. Os produtos e informações neste site não se destinam a diagnosticar, tratar, curar ou prevenir qualquer doença. As notas de evidência apresentadas são baseadas em nossa análise de pesquisas revisadas por pares publicadas e não constituem aconselhamento médico. Sempre consulte seu profissional de saúde antes de iniciar qualquer regime de suplementação.