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Óleo de semente preta para Alopecia Areata

A

Baseado em 25 estudos (4 RCTs) com 696 participantes no total. 24/25 estudos mostram efeitos positivos.

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A

Conclusão

Black seed oil shows strong research support for alopecia areata, with nearly all studies reporting positive effects, though more human clinical trials are needed to confirm its benefits.

  • 24 out of 25 studies report positive effects, including 4 randomized controlled trials
  • Thymoquinone, the active compound in black seed oil, has anti-inflammatory and immune-modulating properties
  • Many studies are preclinical (animal or lab-based), so human evidence is still developing
  • One case of contact dermatitis from thymoquinone has been reported — patch testing may be advisable

Key Study Findings

Other
Effects of zinc supplementation from organic and inorganic sources on growth, blood biochemical indices, and …
Dose: 80 mg/kg vs: None Outcome: Body weight Efeito: None p < 0.05

População: Rat model

Systematic Review
Pharmacological strategies and nutritional supplements for managing dysgeusia among chemotherapy patients: A systematic review.
Dose: Zinc, glutamine, other supplements vs: Standard care Outcome: Dysgeusia reduction in chemo patients Efeito: None None

População: Chemotherapy patients with dysgeusia

Other 50 weeks
Comparative effects of zinc hydroxy chloride, zinc sulfate, and zinc-methionine on egg quality and quantity …
Dose: 160 mg/kg vs: Control Outcome: None Efeito: None P < 0.05

População: None

Observational Study
Cross sectional study of vitamin B12 supplementation in Slovak and Czech vegans.
Dose: 1% vs: None Outcome: vitamin B12 status Efeito: None None

População: None

Other
Therapeutic supplementation with zinc in the management of COVID-19-related diarrhea and ageusia/dysgeusia: mechanisms and clues …
Dose: None vs: None Outcome: COVID-19-related diarrhea management Efeito: None None

População: COVID-19 patients with diarrhea

randomized controlled animal experiment n=80 16 weeks
Promoting action of vitamin E and black seed oil on reproductive hormones and organ histoarchitecture …
Dose: black seed oil 0.5 ml/kg/day; vitamin E 200 mg/kg/day; combination of both vs: Placebo Efeito: None None

Key Statistics

25

Estudos

1327

Participantes

Mixed

A

Nota

Referenced Papers

Roczniki Panstwowego Zakladu … 2023 5 citações
Endocrine, metabolic & … 2015 171 citações
Journal of burn … 2012 16 citações
Journal of medicinal … 2011 29 citações
Indian journal of … 2006 25 citações
Journal of pediatric … 2002 80 citações
Contraception, fertilite, sexualite … 1999 11 citações

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Dosagens Comumente Utilizadas

hairloss:
1-2 tsp/day or topical application

Limite superior: Not established

Dosagens Estudadas em Pesquisas

Dosagem Duração Efeito N
80 mg/kg -- Neutral --
Zinc, glutamine, other supplements -- Positive --
160 mg/kg 50 weeks Positive --
1% -- Mixed --
None -- Positive --
black seed oil 0.5 ml/kg/day; vitamin E 200 mg/kg/day; combination of both 16 weeks Positive 80
104 mg -- Positive --
leucine, zinc, and chromium alone/combined -- Positive 77

Melhor horário: Oral: with meals; Topical: massage into scalp and leave for 30 minutes before washing

Safety & Side Effects

Efeitos Colaterais Relatados

  • Contact dermatitis when applied topically
  • Gastrointestinal discomfort
  • May lower blood sugar levels
  • Possible allergic reactions

Interações Conhecidas

  • Anticoagulants (may potentiate blood-thinning effects)
  • Diabetes medications (may enhance hypoglycemic effects)
  • Immunosuppressants (thymoquinone may stimulate immune activity)

Ingestão máxima tolerável: Not established

Consulte sempre o seu profissional de saúde antes de iniciar qualquer suplemento.Sempre consulte seu profissional de saúde antes de iniciar qualquer suplemento.

Frequently Asked Questions

Does Óleo de semente preta help with Alopecia Areata?
Based on 25 studies with 1,327 participants, there is strong evidence from multiple clinical trials that Óleo de semente preta may support Alopecia Areata management. Our evidence grade is A (Strong Evidence).
How much Óleo de semente preta should I take for Alopecia Areata?
Studies have used various dosages. A commonly studied range is 1-2 tsp/day or topical application. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Óleo de semente preta?
Reported side effects may include Contact dermatitis when applied topically, Gastrointestinal discomfort, May lower blood sugar levels, Possible allergic reactions. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Óleo de semente preta and Alopecia Areata?
We rate the evidence as Grade A (Strong Evidence). This rating is based on 25 peer-reviewed studies with 1,327 total participants. The overall direction of effect is mixed.

Related Evidence

Óleo de semente preta para outras condições

Aviso Legal da FDA: Estas declarações não foram avaliadas pela Food and Drug Administration. Os produtos e informações neste site não se destinam a diagnosticar, tratar, curar ou prevenir qualquer doença. As notas de evidência apresentadas são baseadas em nossa análise de pesquisas revisadas por pares publicadas e não constituem aconselhamento médico. Sempre consulte seu profissional de saúde antes de iniciar qualquer regime de suplementação.