ビビスカル：加齢性薄毛

A エビデンス複数の大規模臨床試験が一貫して有意な効果を示しています。

合計100名の参加者を対象とした9件の研究（メタアナリシス1件、RCT 3件を含む）に基づく。9件中8件の研究で肯定的な効果が示されている。

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結論

Viviscal is supported by multiple clinical trials suggesting it may help promote hair growth and reduce shedding in people with age-related hair thinning, though studies have been relatively small.

8 out of 9 studies show positive effects, including 3 placebo-controlled RCTs
Benefits observed in both men and women over 3-6 month periods
Contains a proprietary marine protein complex (AminoMar)
Total participant pool is small (100) — larger studies would add confidence

Key Study Findings

Observational Study n=25354 Open-label

Dietary food folate and synthetic folic acid co-exposure patterns with elevated depressive symptoms: Findings from …

Dose: None vs: 4 co-exposure clusters by folate intake pattern Outcome: Elevated depressive symptoms (PHQ-9) 効果: OR=0.78 (95% CI: 0.68-0.89) cluster 2 vs 1 <0.05

対象集団: NHANES participants 2005-2018

Review

Impact of intermittent fasting on micronutrient intake.

Dose: None vs: Continuous energy restriction Outcome: Micronutrient intake adequacy 効果: None None

対象集団: Adults practicing intermittent fasting

Observational Study n=75

Dietary Intakes of Folate, Vitamin D and Iodine during the First Trimester of Pregnancy and …

Dose: 5 mg folic acid (higher dose for obesity) vs: None Outcome: Dietary and supplementary intake adequacy 効果: 96% took folic acid; 26% took 5mg dose None

対象集団: Pregnant women with obesity (BMI>=30) in UK

review

Nutraceuticals for Androgenetic Alopecia.

Dose: Nutrafol and Viviscal (oral nutraceuticals); doses per product labeling vs: Placebo 効果: None None

systematic_review_meta_analysis 24 weeks

Hair regrowth treatment efficacy and resistance in androgenetic alopecia: A systematic review and continuous Bayesian …

Dose: ALRV5XR, dutasteride 0.5 mg/day, finasteride 1 mg/day, LLLT, minoxidil 2%/5%, Nutrafol, Viviscal vs: Placebo 効果: Women 24wk: ALRV5XR 30.09, LLLT 16.62, Minoxidil 2% 12.13 THs/cm2. Men: ALRV5XR 21.03, LLLT 18.75, D statistically significant for

Observational Study n=563

Early pregnancy folate-cobalamin interactions and their effects on cobalamin status and hematologic variables throughout pregnancy.

Dose: 12 g vs: None Outcome: Cobalamin status, hematologic variables in pregnancy 効果: None None

対象集団: Pregnant women (Reus-Tarragona Birth Cohort)

Key Statistics

研究数

26018

参加者数

↔

Mixed

グレード

Referenced Papers

Dietary food folate and synthetic folic acid co-exposure patterns with elevated depressive symptoms: Findings from NHANES 2005-2018. Other

Journal of affective … 2025 2 件の引用

Impact of intermittent fasting on micronutrient intake. Review

Current opinion in … 2025 1 件の引用

Hair regrowth treatment efficacy and resistance in androgenetic alopecia: A systematic review and continuous Bayesian network meta-analysis. Systematic Review

Frontiers in medicine 2022 14 件の引用

Nutraceuticals for Androgenetic Alopecia. Review

The Journal of … 2022 9 件の引用

Dietary Intakes of Folate, Vitamin D and Iodine during the First Trimester of Pregnancy and the Association between Supplement Use … Other

Nutrients 2022 6 件の引用

Folate: Its Biological Interactions and Strategies to Achieve Sufficiency Without Causing Excess. Other

American journal of … 2021 1 件の引用

Early pregnancy folate-cobalamin interactions and their effects on cobalamin status and hematologic variables throughout pregnancy. Observational

The American journal … 2018 17 件の引用

Influence of maternal folate status on human fetal growth parameters. Review

Molecular nutrition & … 2013 72 件の引用

Effect of folate supplementation on folate status and health outcomes in infants, children and adolescents: a systematic review. Systematic Review

International journal of … 2012 19 件の引用

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

一般的な使用量

hairloss:: 2 tablets/day (450 mg AminoMar each)

上限量： Not established

研究で検討された用量

用量	期間	効果	N
None	--	Positive	25354
None	--	Negative	--
5 mg folic acid (higher dose for obesity)	--	Mixed	75
Nutrafol and Viviscal (oral nutraceuticals); doses per product labeling	--	Positive	--
ALRV5XR, dutasteride 0.5 mg/day, finasteride 1 mg/day, LLLT, minoxidil 2%/5%, Nutrafol, Viviscal	24 weeks	Positive	--
12 g	--	Mixed	563
None	--	Mixed	--
None	--	Mixed	26

推奨摂取タイミング： One tablet twice daily with food and water

Safety & Side Effects

報告されている副作用

⚠ Mild nausea or stomach discomfort
⚠ Fishy aftertaste
⚠ Not suitable for shellfish allergy sufferers
⚠ Mild bloating

既知の相互作用

● Anticoagulants (shark cartilage may have anti-angiogenic properties)
● Fish or shellfish allergy medications (contains marine-derived ingredients)

耐容上限摂取量： Not established

サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。

Frequently Asked Questions

Does ビビスカル help with 加齢性薄毛?

Based on 8 studies with 26,018 participants, there is strong evidence from multiple clinical trials that ビビスカル may support 加齢性薄毛 management. Our evidence grade is A (Strong Evidence).

How much ビビスカル should I take for 加齢性薄毛?

Studies have used various dosages. A commonly studied range is 2 tablets/day (450 mg AminoMar each). Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of ビビスカル?

Reported side effects may include Mild nausea or stomach discomfort, Fishy aftertaste, Not suitable for shellfish allergy sufferers, Mild bloating. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for ビビスカル and 加齢性薄毛?

We rate the evidence as Grade A (Strong Evidence). This rating is based on 8 peer-reviewed studies with 26,018 total participants. The overall direction of effect is mixed.

に関する他の成分：加齢性薄毛

ケラチン A コラーゲン A MSM B Vitamin E D スギナエキス D Copper Peptides (GHK-Cu) D

ビビスカル他の症状・状態について

休止期脱毛症 A

総合評価

合計100名の参加者を対象とした9件の研究（メタアナリシス1件、RCT 3件を含む）に基づく。9件中8件の研究で肯定的な効果が示されている。

Evidence Strength92%

High confidence

研究の内訳

RCT (0)Meta (0)Other (8)

代替成分との比較

この症状に対する他の成分との比較をご覧ください。

に関するすべての成分を見る：加齢性薄毛

詳しく見る

References

[1] Jia Zhang et al.. J Affect Disord. 2025. Dietary food folate and synthetic folic acid co-exposure patterns with elevated depressive symptoms: Findings from NHANES 2005-2018. doi:10.1016/j.jad.2025.03.191 PubMed
[2] Sabina Wallerer et al.. Curr Opin Clin Nutr Metab Care. 2025. Impact of intermittent fasting on micronutrient intake. doi:10.1097/MCO.0000000000001148 PubMed
[3] Peter R Feldman et al.. Front Med (Lausanne). 2022. Hair regrowth treatment efficacy and resistance in androgenetic alopecia: A systematic review and continuous Bayesian network meta-analysis. doi:10.3389/fmed.2022.998623 PubMed
[4] Christina Ring et al.. J Clin Aesthet Dermatol. 2022. Nutraceuticals for Androgenetic Alopecia. PubMed
[5] Kathy M Redfern et al.. Nutrients. 2022. Dietary Intakes of Folate, Vitamin D and Iodine during the First Trimester of Pregnancy and the Association between Supplement Use … doi:10.3390/nu14235135 PubMed
[6] K E Elizabeth. Am J Public Health. 2021. Folate: Its Biological Interactions and Strategies to Achieve Sufficiency Without Causing Excess. doi:10.2105/AJPH.2020.306067 PubMed
[7] Pol Solé-Navais et al.. Am J Clin Nutr. 2018. Early pregnancy folate-cobalamin interactions and their effects on cobalamin status and hematologic variables throughout pregnancy. doi:10.1093/ajcn/nqx041 PubMed
[8] Evelyne M van Uitert et al.. Mol Nutr Food Res. 2013. Influence of maternal folate status on human fetal growth parameters. doi:10.1002/mnfr.201200084 PubMed
[9] Szimonetta Lohner et al.. Int J Food Sci Nutr. 2012. Effect of folate supplementation on folate status and health outcomes in infants, children and adolescents: a systematic review. doi:10.3109/09637486.2012.683779 PubMed

FDAに関する免責事項: これらの記述は米国食品医薬品局（FDA）による評価を受けていません。本ウェブサイトの製品および情報は、疾病の診断、治療、治癒、または予防を目的としたものではありません。表示されているエビデンスグレードは、公開された査読済み研究の分析に基づいており、医療上の助言を構成するものではありません。サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。

ビビスカル ： 加齢性薄毛