コラーゲン：加齢性薄毛

Q: Does コラーゲン help with 加齢性薄毛?

Based on 5 studies with 1,970 participants, there is strong evidence from multiple clinical trials that コラーゲン may support 加齢性薄毛 management. Our evidence grade is A (Strong Evidence).

Q: How much コラーゲン should I take for 加齢性薄毛?

Studies have used various dosages. A commonly studied range is 2.5-15 g/day. Always consult your healthcare provider before starting any supplement regimen.

Q: Are there side effects of コラーゲン?

Reported side effects may include Mild digestive discomfort (bloating, fullness), Unpleasant taste (marine collagen), Rare allergic reactions in individuals with fish or shellfish allergies. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

Q: How strong is the evidence for コラーゲン and 加齢性薄毛?

We rate the evidence as Grade A (Strong Evidence). This rating is based on 5 peer-reviewed studies with 1,970 total participants. The overall direction of effect is positive.

A エビデンス複数の大規模臨床試験が一貫して有意な効果を示しています。

合計426名の参加者を対象とした5件の研究（RCT 1件を含む）に基づく。5件中5件の研究で肯定的な効果が示されている。

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結論

Collagen supplements show good evidence for supporting hair thickness and growth as part of an age-related hair thinning regimen, though it is usually studied in combination with other nutrients.

All 5 studies report positive effects on hair growth and thickness
Hydrolyzed collagen peptides may activate signaling pathways that support hair follicle health
Collagen is often combined with other ingredients (iron, selenium, amino acids) in hair supplements
Both marine and fish collagen have shown promise in laboratory and clinical studies

Key Study Findings

Prospective Open-Label Interventional Study n=343 4 weeks Open-label

Effect of a Hydrolyzed Collagen, Vitamin, and Zinc Containing Nutritional Supplement on Telogen Effluvium.

Dose: Pilopeptan Intensive (hydrolyzed collagen, Group B vitamins, zinc); daily for 1 month vs: Placebo 効果: Significant improvements in all hair parameters at T1 and T2 (P < 0.001) p<0.001

Review

Biomarker-Guided Dietary Supplementation: A Narrative Review of Precision in Personalized Nutrition.

Dose: None vs: None Outcome: Microbiome composition 効果: None None

対象集団: None

randomized controlled trial n=83 12 weeks

Efficacy and tolerability of an oral supplement containing amino acids, iron, selenium, and marine hydrolyzed …

Dose: 1 tablet per day (hydrolyzed fish-origin collagen 300 mg/dose) plus standard drug treatment vs: Placebo 効果: GAS at week 12: Group A 1.67 ± 0.16 vs. Group B 0.66 ± 0.20 (p<0.001); 50% vs 23% achieved GAS ≥2 <0.001

Controlled Clinical Trial n=843 4.3 weeks

Micronutrient Gaps and Supplement Use in a Diverse Cohort of Pregnant Women.

Dose: 91% vs: None Outcome: folate status 効果: None None

対象集団: Pregnant women

Observational Study n=701

Nutrient intakes from supplement and factors associated with supplement use among breast cancer survivors: A …

Dose: 66.5% vs: None Outcome: None 効果: None None

対象集団: supplement use among breast cancer

Key Statistics

研究数

1970

参加者数

↑

Positive

グレード

Referenced Papers

Effect of a Hydrolyzed Collagen, Vitamin, and Zinc Containing Nutritional Supplement on Telogen Effluvium. Other

International journal of … 2025

Biomarker-Guided Dietary Supplementation: A Narrative Review of Precision in Personalized Nutrition. Review

Nutrients 2024 12 件の引用

Efficacy and tolerability of an oral supplement containing amino acids, iron, selenium, and marine hydrolyzed collagen in subjects with hair … RCT

Skin research and … 2023 11 件の引用

Micronutrient Gaps and Supplement Use in a Diverse Cohort of Pregnant Women. Other

Nutrients 2023 11 件の引用

Nutrient intakes from supplement and factors associated with supplement use among breast cancer survivors: A cross-sectional study. Other

European journal of … 2021 5 件の引用

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

一般的な使用量

general:: 2.5-15 g/day

上限量： Not established

研究で検討された用量

用量	期間	効果	N
Pilopeptan Intensive (hydrolyzed collagen, Group B vitamins, zinc); daily for 1 month	4 weeks	Positive	343
None	--	Positive	--
1 tablet per day (hydrolyzed fish-origin collagen 300 mg/dose) plus standard drug treatment	12 weeks	Positive	83
91%	4.3 weeks	Positive	843
66.5%	--	Mixed	701

推奨摂取タイミング： On an empty stomach or with vitamin C for enhanced collagen synthesis

Safety & Side Effects

報告されている副作用

⚠ Mild digestive discomfort (bloating, fullness)
⚠ Unpleasant taste (marine collagen)
⚠ Rare allergic reactions in individuals with fish or shellfish allergies

既知の相互作用

● No significant drug interactions established
● Calcium supplements (some collagen products contain added calcium)

耐容上限摂取量： Not established

サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。

Frequently Asked Questions

Does コラーゲン help with 加齢性薄毛?

Based on 5 studies with 1,970 participants, there is strong evidence from multiple clinical trials that コラーゲン may support 加齢性薄毛 management. Our evidence grade is A (Strong Evidence).

How much コラーゲン should I take for 加齢性薄毛?

Studies have used various dosages. A commonly studied range is 2.5-15 g/day. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of コラーゲン?

Reported side effects may include Mild digestive discomfort (bloating, fullness), Unpleasant taste (marine collagen), Rare allergic reactions in individuals with fish or shellfish allergies. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for コラーゲン and 加齢性薄毛?

We rate the evidence as Grade A (Strong Evidence). This rating is based on 5 peer-reviewed studies with 1,970 total participants. The overall direction of effect is positive.

に関する他の成分：加齢性薄毛

ケラチン A ビビスカル A MSM B Vitamin E D スギナエキス D Copper Peptides (GHK-Cu) D

総合評価

合計426名の参加者を対象とした5件の研究（RCT 1件を含む）に基づく。5件中5件の研究で肯定的な効果が示されている。

Evidence Strength92%

High confidence

研究の内訳

RCT (1)Meta (0)Other (4)

代替成分との比較

この症状に対する他の成分との比較をご覧ください。

に関するすべての成分を見る：加齢性薄毛

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References

[1] Eva María Arias et al.. Int J Trichology. 2025. Effect of a Hydrolyzed Collagen, Vitamin, and Zinc Containing Nutritional Supplement on Telogen Effluvium. doi:10.4103/ijt.ijt_70_24 PubMed
[2] Evgeny Pokushalov et al.. Nutrients. 2024. Biomarker-Guided Dietary Supplementation: A Narrative Review of Precision in Personalized Nutrition. doi:10.3390/nu16234033 PubMed
[3] Massimo Milani et al.. Skin Res Technol. 2023. Efficacy and tolerability of an oral supplement containing amino acids, iron, selenium, and marine hydrolyzed collagen in subjects with hair … doi:10.1111/srt.13381 PubMed
[4] Sarah A Crawford et al.. Nutrients. 2023. Micronutrient Gaps and Supplement Use in a Diverse Cohort of Pregnant Women. doi:10.3390/nu15143228 PubMed
[5] Jiyoung Youn et al.. Eur J Cancer Care (Engl). 2021. Nutrient intakes from supplement and factors associated with supplement use among breast cancer survivors: A cross-sectional study. doi:10.1111/ecc.13447 PubMed

FDAに関する免責事項: これらの記述は米国食品医薬品局（FDA）による評価を受けていません。本ウェブサイトの製品および情報は、疾病の診断、治療、治癒、または予防を目的としたものではありません。表示されているエビデンスグレードは、公開された査読済み研究の分析に基づいており、医療上の助言を構成するものではありません。サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。

コラーゲン ： 加齢性薄毛