Viviscal 用于 年龄相关性头发稀疏
A 证据 多项大型临床试验一致显示出显著的益处。基于9项研究（1项荟萃分析、3项RCT），共100名参与者。8/9项研究显示积极效果。
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A
结论
Viviscal is supported by multiple clinical trials suggesting it may help promote hair growth and reduce shedding in people with age-related hair thinning, though studies have been relatively small.
- 8 out of 9 studies show positive effects, including 3 placebo-controlled RCTs
- Benefits observed in both men and women over 3-6 month periods
- Contains a proprietary marine protein complex (AminoMar)
- Total participant pool is small (100) — larger studies would add confidence
Key Study Findings
Observational Study
n=25354
Open-label
Dietary food folate and synthetic folic acid co-exposure patterns with elevated depressive symptoms: Findings from …
Dose: None
vs: 4 co-exposure clusters by folate intake pattern
Outcome: Elevated depressive symptoms (PHQ-9)
效果: OR=0.78 (95% CI: 0.68-0.89) cluster 2 vs 1
<0.05
研究人群: NHANES participants 2005-2018
Review
Impact of intermittent fasting on micronutrient intake.
Dose: None
vs: Continuous energy restriction
Outcome: Micronutrient intake adequacy
效果: None
None
研究人群: Adults practicing intermittent fasting
Observational Study
n=75
Dietary Intakes of Folate, Vitamin D and Iodine during the First Trimester of Pregnancy and …
Dose: 5 mg folic acid (higher dose for obesity)
vs: None
Outcome: Dietary and supplementary intake adequacy
效果: 96% took folic acid; 26% took 5mg dose
None
研究人群: Pregnant women with obesity (BMI>=30) in UK
review
Nutraceuticals for Androgenetic Alopecia.
Dose: Nutrafol and Viviscal (oral nutraceuticals); doses per product labeling
vs: Placebo
效果: None
None
systematic_review_meta_analysis
24 weeks
Hair regrowth treatment efficacy and resistance in androgenetic alopecia: A systematic review and continuous Bayesian …
Dose: ALRV5XR, dutasteride 0.5 mg/day, finasteride 1 mg/day, LLLT, minoxidil 2%/5%, Nutrafol, Viviscal
vs: Placebo
效果: Women 24wk: ALRV5XR 30.09, LLLT 16.62, Minoxidil 2% 12.13 THs/cm2. Men: ALRV5XR 21.03, LLLT 18.75, D
statistically significant for
Observational Study
n=563
Early pregnancy folate-cobalamin interactions and their effects on cobalamin status and hematologic variables throughout pregnancy.
Dose: 12 g
vs: None
Outcome: Cobalamin status, hematologic variables in pregnancy
效果: None
None
研究人群: Pregnant women (Reus-Tarragona Birth Cohort)
Key Statistics
8
研究数量
26018
受试者
↔
Mixed
A
等级
Referenced Papers
Journal of affective …
2025
2 次引用
Current opinion in …
2025
1 次引用
Hair regrowth treatment efficacy and resistance in androgenetic alopecia: A systematic review and continuous Bayesian network meta-analysis.
Systematic Review
Frontiers in medicine
2022
14 次引用
The Journal of …
2022
9 次引用
Nutrients
2022
6 次引用
Folate: Its Biological Interactions and Strategies to Achieve Sufficiency Without Causing Excess.
Other
American journal of …
2021
1 次引用
The American journal …
2018
17 次引用
Molecular nutrition & …
2013
72 次引用
Effect of folate supplementation on folate status and health outcomes in infants, children and adolescents: a systematic review.
Systematic Review
International journal of …
2012
19 次引用
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
常用剂量
- hairloss:
- 2 tablets/day (450 mg AminoMar each)
上限： Not established
研究中使用的剂量
| 剂量 | 持续时间 | 效果 | N |
|---|---|---|---|
| None | -- | Positive | 25354 |
| None | -- | Negative | -- |
| 5 mg folic acid (higher dose for obesity) | -- | Mixed | 75 |
| Nutrafol and Viviscal (oral nutraceuticals); doses per product labeling | -- | Positive | -- |
| ALRV5XR, dutasteride 0.5 mg/day, finasteride 1 mg/day, LLLT, minoxidil 2%/5%, Nutrafol, Viviscal | 24 weeks | Positive | -- |
| 12 g | -- | Mixed | 563 |
| None | -- | Mixed | -- |
| None | -- | Mixed | 26 |
最佳服用时间： One tablet twice daily with food and water
Safety & Side Effects
已报告的副作用
- ⚠ Mild nausea or stomach discomfort
- ⚠ Fishy aftertaste
- ⚠ Not suitable for shellfish allergy sufferers
- ⚠ Mild bloating
已知相互作用
- ● Anticoagulants (shark cartilage may have anti-angiogenic properties)
- ● Fish or shellfish allergy medications (contains marine-derived ingredients)
可耐受最高摄入量： Not established
在开始服用任何补充剂之前，请务必咨询您的医疗保健提供者。
Frequently Asked Questions
Does Viviscal help with 年龄相关性头发稀疏?
Based on 8 studies with 26,018 participants, there is strong evidence from multiple clinical trials that Viviscal may support 年龄相关性头发稀疏 management. Our evidence grade is A (Strong Evidence).
How much Viviscal should I take for 年龄相关性头发稀疏?
Studies have used various dosages. A commonly studied range is 2 tablets/day (450 mg AminoMar each). Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Viviscal?
Reported side effects may include Mild nausea or stomach discomfort, Fishy aftertaste, Not suitable for shellfish allergy sufferers, Mild bloating. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Viviscal and 年龄相关性头发稀疏?
We rate the evidence as Grade A (Strong Evidence). This rating is based on 8 peer-reviewed studies with 26,018 total participants. The overall direction of effect is mixed.
Related Evidence
其他成分用于 年龄相关性头发稀疏
Viviscal 用于其他健康状况
References
- [1] Jia Zhang et al.. J Affect Disord. 2025. Dietary food folate and synthetic folic acid co-exposure patterns with elevated depressive symptoms: Findings from NHANES 2005-2018. doi:10.1016/j.jad.2025.03.191 PubMed
- [2] Sabina Wallerer et al.. Curr Opin Clin Nutr Metab Care. 2025. Impact of intermittent fasting on micronutrient intake. doi:10.1097/MCO.0000000000001148 PubMed
- [3] Peter R Feldman et al.. Front Med (Lausanne). 2022. Hair regrowth treatment efficacy and resistance in androgenetic alopecia: A systematic review and continuous Bayesian network meta-analysis. doi:10.3389/fmed.2022.998623 PubMed
- [4] Christina Ring et al.. J Clin Aesthet Dermatol. 2022. Nutraceuticals for Androgenetic Alopecia. PubMed
- [5] Kathy M Redfern et al.. Nutrients. 2022. Dietary Intakes of Folate, Vitamin D and Iodine during the First Trimester of Pregnancy and the Association between Supplement Use … doi:10.3390/nu14235135 PubMed
- [6] K E Elizabeth. Am J Public Health. 2021. Folate: Its Biological Interactions and Strategies to Achieve Sufficiency Without Causing Excess. doi:10.2105/AJPH.2020.306067 PubMed
- [7] Pol Solé-Navais et al.. Am J Clin Nutr. 2018. Early pregnancy folate-cobalamin interactions and their effects on cobalamin status and hematologic variables throughout pregnancy. doi:10.1093/ajcn/nqx041 PubMed
- [8] Evelyne M van Uitert et al.. Mol Nutr Food Res. 2013. Influence of maternal folate status on human fetal growth parameters. doi:10.1002/mnfr.201200084 PubMed
- [9] Szimonetta Lohner et al.. Int J Food Sci Nutr. 2012. Effect of folate supplementation on folate status and health outcomes in infants, children and adolescents: a systematic review. doi:10.3109/09637486.2012.683779 PubMed
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