ノコギリヤシ：男性型・女性型脱毛症（AGA）

Q: Does ノコギリヤシ help with 男性型・女性型脱毛症（AGA）?

Based on 22 studies with 2,123 participants, there is strong evidence from multiple clinical trials that ノコギリヤシ may support 男性型・女性型脱毛症（AGA） management. Our evidence grade is A (Strong Evidence).

Q: How much ノコギリヤシ should I take for 男性型・女性型脱毛症（AGA）?

Studies have used various dosages. A commonly studied range is 320 mg/day. Always consult your healthcare provider before starting any supplement regimen.

Q: Are there side effects of ノコギリヤシ?

Reported side effects may include Mild gastrointestinal upset (nausea, diarrhea), Headache, Dizziness, Rare: decreased libido. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

Q: How strong is the evidence for ノコギリヤシ and 男性型・女性型脱毛症（AGA）?

We rate the evidence as Grade A (Strong Evidence). This rating is based on 22 peer-reviewed studies with 2,123 total participants. The overall direction of effect is positive.

A エビデンス複数の大規模臨床試験が一貫して有意な効果を示しています。

合計2,123名の参加者を対象とした21件の研究（メタアナリシス2件、RCT 4件を含む）に基づく。21件中20件の研究で肯定的な効果が示されている。

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結論

Saw palmetto is well-supported by clinical research as a natural supplement that may help slow hair loss and support regrowth in androgenetic alopecia by naturally inhibiting DHT production.

95% of studies (20/21) show positive effects, including 4 RCTs and 2 meta-analyses
Works as a natural 5-alpha reductase inhibitor, reducing DHT levels
Both oral supplementation and topical application have demonstrated benefits
Generally well-tolerated, though less potent than prescription finasteride

Key Study Findings

Review

The Over-The-Counter Finasteride Alternative: A Critical Review of Saw Palmetto's Efficacy, Safety, and Regulatory Concerns.

Dose: None vs: None Outcome: None 効果: None None

対象集団: None

RCT n=80 24 weeks Double-blind

Oral Supplementation with l-Cystine, Serenoa repens, Cucurbita pepo, and Pygeum africanum in Chronic Telogen Effluvium …

Dose: 1 capsule daily (l-Cystine, Serenoa repens, Cucurbita pepo, Pygeum africanum, vitamins, micronutrien vs: Placebo 効果: MD=+12.3 hairs/cm2 at 6 months p<0.05

narrative review

Addressing the Root Causes of Female Hair Loss and Non-Pharmaceutical Interventions.

Dose: None vs: Placebo 効果: None None

narrative review

Herbal Remedies for Hair Loss: A Review of Efficacy and Safety.

Dose: varies by remedy and study vs: Placebo 効果: None None

systematic review n=1658 Double-blind

Effects of dietary supplements on androgenetic alopecia: a systematic review and network meta-analysis.

Dose: various dietary supplements (Nutrafol, apple extract, tocotrienols, pumpkin seed oil, Cistanche/Lami vs: Placebo 効果: None None

review Single-blind

Do Non-Prescription Products Help in Managing Androgenic Alopecia?

Dose: Various non-prescription agents: procyanidin, cetirizine, caffeine, Oryza sativa bran, pumpkin seed vs: Placebo 効果: Considerable improvements in one or more parameters across 13 included studies None

Key Statistics

研究数

2123

参加者数

↑

Positive

グレード

Referenced Papers

The Over-The-Counter Finasteride Alternative: A Critical Review of Saw Palmetto's Efficacy, Safety, and Regulatory Concerns. Other

International journal of … 2026 1 件の引用

Herbal Remedies for Hair Loss: A Review of Efficacy and Safety. Review

Skin appendage disorders 2025 7 件の引用

Oral Supplementation with l-Cystine, Serenoa repens, Cucurbita pepo, and Pygeum africanum in Chronic Telogen Effluvium and Androgenetic Alopecia: A Double-Blind, … Other

Skin appendage disorders 2025 3 件の引用

Computational drug discovery of potential 5α-reductase phytochemical inhibitors and hair growth promotion using in silico techniques. Other

Frontiers in bioinformatics 2025 2 件の引用

A proprietary lipidosterolic extract of Serenoa repens promotes hair growth through mechanisms that extend beyond 5-alpha reductase inhibition: Insights from … Other

International journal of … 2025 1 件の引用

Impact of a Novel Dietary Supplement on Efficacy of Pharmacological Treatments for Androgenic Alopecia: A Real-Life, Multicenter, Randomized, Assessor-Blinded Trial … RCT

Journal of cosmetic … 2025 1 件の引用

Do Non-Prescription Products Help in Managing Androgenic Alopecia? Review

Skin appendage disorders 2025 1 件の引用

Addressing the Root Causes of Female Hair Loss and Non-Pharmaceutical Interventions. Review

Journal of drugs … 2025

Effects of dietary supplements on androgenetic alopecia: a systematic review and network meta-analysis. Systematic Review

Frontiers in nutrition 2025

Complementary and alternative supplements: a review of dermatologic effectiveness for androgenetic alopecia. Review

Proceedings (Baylor University. … 2024 14 件の引用

Emerging and traditional 5-α reductase inhibitors and androgen receptor antagonists for male androgenetic alopecia. Review

Expert opinion on … 2024 8 件の引用

An Overview of Commonly Used Natural Alternatives for the Treatment of Androgenetic Alopecia, with Special Emphasis on Rosemary Oil. Review

Clinical, cosmetic and … 2024 7 件の引用

A Comparative Study of Topical Procapil With Platelet-Rich Plasma Therapy Versus Topical Redensyl, Saw Palmetto, and Biotin With Platelet-Rich Plasma … Other

Cureus 2023 9 件の引用

Real-World, Open-Label Study of the Efficacy and Safety of a Novel Serum in Androgenetic Alopecia. Other

Journal of drugs … 2023 8 件の引用

Oral and Topical Administration of a Standardized Saw Palmetto Oil Reduces Hair Fall and Improves the Hair Growth in Androgenetic … Case Report

Clinical, cosmetic and … 2023 8 件の引用

Natural products for male androgenetic alopecia. Review

Dermatologic therapy 2022 41 件の引用

A review of the treatment of male pattern hair loss. Review

Expert opinion on … 2020 147 件の引用

Herbal preparations for the treatment of hair loss. Review

Archives of dermatological … 2020 51 件の引用

Natural Hair Supplement: Friend or Foe? Saw Palmetto, a Systematic Review in Alopecia. Review

Skin appendage disorders 2020 24 件の引用

An overview of herbal alternatives in androgenetic alopecia. Review

Journal of cosmetic … 2019 100 件の引用

Comparitive effectiveness of finasteride vs Serenoa repens in male androgenetic alopecia: a two-year study. RCT

International journal of … 2012 69 件の引用

Inhibition of inflammatory gene expression in keratinocytes using a composition containing carnitine, thioctic Acid and saw palmetto extract. Other

Evidence-based complementary and … 2011 27 件の引用

Sensitization to saw palmetto and minoxidil in separate topical extemporaneous treatments for androgenetic alopecia. Case Report

The Australasian journal … 2002 20 件の引用

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

一般的な使用量

general:: 320 mg/day
hairloss:: 320 mg/day standardized extract

上限量： Not established

研究で検討された用量

用量	期間	効果	N
None	--	Neutral	--
1 capsule daily (l-Cystine, Serenoa repens, Cucurbita pepo, Pygeum africanum, vitamins, micronutrien	24 weeks	Positive	80
None	--	Positive	--
varies by remedy and study	--	Positive	--
various dietary supplements (Nutrafol, apple extract, tocotrienols, pumpkin seed oil, Cistanche/Lami	--	Positive	1658
Various non-prescription agents: procyanidin, cetirizine, caffeine, Oryza sativa bran, pumpkin seed	--	Positive	--
None	--	Positive	--
USPlus DERM (lipidosterolic extract of Serenoa repens) at 0.4 and 10 μg/mL in hair follicle organ cu	--	Positive	--

推奨摂取タイミング： With meals to reduce gastrointestinal side effects

Safety & Side Effects

報告されている副作用

⚠ Mild gastrointestinal upset (nausea, diarrhea)
⚠ Headache
⚠ Dizziness
⚠ Rare: decreased libido

既知の相互作用

● Anticoagulants and antiplatelet drugs (may increase bleeding risk)
● Oral contraceptives and hormone replacement therapy (anti-androgenic effects)
● Finasteride and dutasteride (additive 5-alpha-reductase inhibition)

耐容上限摂取量： Not established

サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。

Frequently Asked Questions

Does ノコギリヤシ help with 男性型・女性型脱毛症（AGA）?

Based on 22 studies with 2,123 participants, there is strong evidence from multiple clinical trials that ノコギリヤシ may support 男性型・女性型脱毛症（AGA） management. Our evidence grade is A (Strong Evidence).

How much ノコギリヤシ should I take for 男性型・女性型脱毛症（AGA）?

Studies have used various dosages. A commonly studied range is 320 mg/day. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of ノコギリヤシ?

Reported side effects may include Mild gastrointestinal upset (nausea, diarrhea), Headache, Dizziness, Rare: decreased libido. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for ノコギリヤシ and 男性型・女性型脱毛症（AGA）?

We rate the evidence as Grade A (Strong Evidence). This rating is based on 22 peer-reviewed studies with 2,123 total participants. The overall direction of effect is positive.

に関する他の成分：男性型・女性型脱毛症（AGA）

ミノキシジル A フィナステリド A PRP療法 A デュタステリド A オメガ3脂肪酸 A マイクロニードリング A

ノコギリヤシ他の症状・状態について

女性型脱毛症 B

総合評価

合計2,123名の参加者を対象とした21件の研究（メタアナリシス2件、RCT 4件を含む）に基づく。21件中20件の研究で肯定的な効果が示されている。

Evidence Strength92%

High confidence

研究の内訳

RCT (2)Meta (0)Other (20)

代替成分との比較

この症状に対する他の成分との比較をご覧ください。

に関するすべての成分を見る：男性型・女性型脱毛症（AGA）

詳しく見る

References

[1] Kevin T Nguyen et al.. Int J Dermatol. 2026. The Over-The-Counter Finasteride Alternative: A Critical Review of Saw Palmetto's Efficacy, Safety, and Regulatory Concerns. doi:10.1111/ijd.17987 PubMed
[2] Azhar Ahmed et al.. Skin Appendage Disord. 2025. Herbal Remedies for Hair Loss: A Review of Efficacy and Safety. doi:10.1159/000542876 PubMed
[3] Jaime Piquero-Casals et al.. Skin Appendage Disord. 2025. Oral Supplementation with l-Cystine, Serenoa repens, Cucurbita pepo, and Pygeum africanum in Chronic Telogen Effluvium and Androgenetic Alopecia: A Double-Blind, … doi:10.1159/000540081 PubMed
[4] Behnam Hasannejad-Asl et al.. Front Bioinform. 2025. Computational drug discovery of potential 5α-reductase phytochemical inhibitors and hair growth promotion using in silico techniques. doi:10.3389/fbinf.2025.1570101 PubMed
[5] David Broadley et al.. Int J Cosmet Sci. 2025. A proprietary lipidosterolic extract of Serenoa repens promotes hair growth through mechanisms that extend beyond 5-alpha reductase inhibition: Insights from … doi:10.1111/ics.70035 PubMed
[6] Massimo Milani et al.. J Cosmet Dermatol. 2025. Impact of a Novel Dietary Supplement on Efficacy of Pharmacological Treatments for Androgenic Alopecia: A Real-Life, Multicenter, Randomized, Assessor-Blinded Trial … doi:10.1111/jocd.70388 PubMed
[7] Aditya K Gupta et al.. Skin Appendage Disord. 2025. Do Non-Prescription Products Help in Managing Androgenic Alopecia? doi:10.1159/000542880 PubMed
[8] Adam Leavitt et al.. J Drugs Dermatol. 2025. Addressing the Root Causes of Female Hair Loss and Non-Pharmaceutical Interventions. doi:10.36849/JDD.8763 PubMed
[9] Lei Zhou et al.. Front Nutr. 2025. Effects of dietary supplements on androgenetic alopecia: a systematic review and network meta-analysis. doi:10.3389/fnut.2025.1719711 PubMed
[10] Promise Ufomadu. Proc (Bayl Univ Med Cent). 2024. Complementary and alternative supplements: a review of dermatologic effectiveness for androgenetic alopecia. doi:10.1080/08998280.2023.2263829 PubMed
[11] Aditya K Gupta et al.. Expert Opin Emerg Drugs. 2024. Emerging and traditional 5-α reductase inhibitors and androgen receptor antagonists for male androgenetic alopecia. doi:10.1080/14728214.2024.2346590 PubMed
[12] Nouf F Bin Rubaian et al.. Clin Cosmet Investig Dermatol. 2024. An Overview of Commonly Used Natural Alternatives for the Treatment of Androgenetic Alopecia, with Special Emphasis on Rosemary Oil. doi:10.2147/CCID.S470989 PubMed
[13] Pavithra Tr et al.. Cureus. 2023. A Comparative Study of Topical Procapil With Platelet-Rich Plasma Therapy Versus Topical Redensyl, Saw Palmetto, and Biotin With Platelet-Rich Plasma … doi:10.7759/cureus.38696 PubMed
[14] Jeffrey Rapaport et al.. J Drugs Dermatol. 2023. Real-World, Open-Label Study of the Efficacy and Safety of a Novel Serum in Androgenetic Alopecia. doi:10.36849/JDD.7403 PubMed
[15] Heggar Venkataramana Sudeep et al.. Clin Cosmet Investig Dermatol. 2023. Oral and Topical Administration of a Standardized Saw Palmetto Oil Reduces Hair Fall and Improves the Hair Growth in Androgenetic … doi:10.2147/CCID.S435795 PubMed
[16] Aditya K Gupta et al.. Dermatol Ther. 2022. Natural products for male androgenetic alopecia. doi:10.1111/dth.15323 PubMed
[17] Katherine York et al.. Expert Opin Pharmacother. 2020. A review of the treatment of male pattern hair loss. doi:10.1080/14656566.2020.1721463 PubMed
[18] Ana Zgonc Škulj et al.. Arch Dermatol Res. 2020. Herbal preparations for the treatment of hair loss. doi:10.1007/s00403-019-02003-x PubMed
[19] Evyatar Evron et al.. Skin Appendage Disord. 2020. Natural Hair Supplement: Friend or Foe? Saw Palmetto, a Systematic Review in Alopecia. doi:10.1159/000509905 PubMed
[20] Maria Yusuf Dhariwala et al.. J Cosmet Dermatol. 2019. An overview of herbal alternatives in androgenetic alopecia. doi:10.1111/jocd.12930 PubMed
[21] A Rossi et al.. Int J Immunopathol Pharmacol. 2012. Comparitive effectiveness of finasteride vs Serenoa repens in male androgenetic alopecia: a two-year study. doi:10.1177/039463201202500435 PubMed
[22] Sridar Chittur et al.. Evid Based Complement Alternat Med. 2011. Inhibition of inflammatory gene expression in keratinocytes using a composition containing carnitine, thioctic Acid and saw palmetto extract. doi:10.1093/ecam/nep102 PubMed
[23] Rodney D Sinclair et al.. Australas J Dermatol. 2002. Sensitization to saw palmetto and minoxidil in separate topical extemporaneous treatments for androgenetic alopecia. doi:10.1046/j.1440-0960.2002.00620.x PubMed

FDAに関する免責事項: これらの記述は米国食品医薬品局（FDA）による評価を受けていません。本ウェブサイトの製品および情報は、疾病の診断、治療、治癒、または予防を目的としたものではありません。表示されているエビデンスグレードは、公開された査読済み研究の分析に基づいており、医療上の助言を構成するものではありません。サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。

ノコギリヤシ ： 男性型・女性型脱毛症（AGA）