쏘팔메토 관련 안드로겐성 탈모증
A 근거 여러 대규모 임상 시험이 일관되게 유의미한 효과를 보여줍니다.총 2,123명의 참여자를 대상으로 한 21건의 연구(메타분석 2건, RCT 4건)에 근거합니다. 21건 중 20건의 연구에서 긍정적인 효과가 나타났습니다.
결론
Saw palmetto is well-supported by clinical research as a natural supplement that may help slow hair loss and support regrowth in androgenetic alopecia by naturally inhibiting DHT production.
- 95% of studies (20/21) show positive effects, including 4 RCTs and 2 meta-analyses
- Works as a natural 5-alpha reductase inhibitor, reducing DHT levels
- Both oral supplementation and topical application have demonstrated benefits
- Generally well-tolerated, though less potent than prescription finasteride
Key Study Findings
대상 집단: None
Key Statistics
22
연구
2123
참여자
Positive
등급
Referenced Papers
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
일반적으로 사용되는 용량
- general:
- 320 mg/day
- hairloss:
- 320 mg/day standardized extract
상한량: Not established
연구에서 사용된 용량
| 용량 | 기간 | 효과 | N |
|---|---|---|---|
| None | -- | Neutral | -- |
| 1 capsule daily (l-Cystine, Serenoa repens, Cucurbita pepo, Pygeum africanum, vitamins, micronutrien | 24 weeks | Positive | 80 |
| None | -- | Positive | -- |
| varies by remedy and study | -- | Positive | -- |
| various dietary supplements (Nutrafol, apple extract, tocotrienols, pumpkin seed oil, Cistanche/Lami | -- | Positive | 1658 |
| Various non-prescription agents: procyanidin, cetirizine, caffeine, Oryza sativa bran, pumpkin seed | -- | Positive | -- |
| None | -- | Positive | -- |
| USPlus DERM (lipidosterolic extract of Serenoa repens) at 0.4 and 10 μg/mL in hair follicle organ cu | -- | Positive | -- |
권장 복용 시간: With meals to reduce gastrointestinal side effects
Safety & Side Effects
보고된 부작용
- ⚠ Mild gastrointestinal upset (nausea, diarrhea)
- ⚠ Headache
- ⚠ Dizziness
- ⚠ Rare: decreased libido
알려진 상호작용
- ● Anticoagulants and antiplatelet drugs (may increase bleeding risk)
- ● Oral contraceptives and hormone replacement therapy (anti-androgenic effects)
- ● Finasteride and dutasteride (additive 5-alpha-reductase inhibition)
일일 최대 섭취 허용량: Not established
건강기능식품을 복용하기 전에 반드시 의료 전문가와 상담하십시오.
Frequently Asked Questions
Does 쏘팔메토 help with 안드로겐성 탈모증?
How much 쏘팔메토 should I take for 안드로겐성 탈모증?
Are there side effects of 쏘팔메토?
How strong is the evidence for 쏘팔메토 and 안드로겐성 탈모증?
Related Evidence
References
- [1] Kevin T Nguyen et al.. Int J Dermatol. 2026. The Over-The-Counter Finasteride Alternative: A Critical Review of Saw Palmetto's Efficacy, Safety, and Regulatory Concerns. doi:10.1111/ijd.17987 PubMed
- [2] Azhar Ahmed et al.. Skin Appendage Disord. 2025. Herbal Remedies for Hair Loss: A Review of Efficacy and Safety. doi:10.1159/000542876 PubMed
- [3] Jaime Piquero-Casals et al.. Skin Appendage Disord. 2025. Oral Supplementation with l-Cystine, Serenoa repens, Cucurbita pepo, and Pygeum africanum in Chronic Telogen Effluvium and Androgenetic Alopecia: A Double-Blind, … doi:10.1159/000540081 PubMed
- [4] Behnam Hasannejad-Asl et al.. Front Bioinform. 2025. Computational drug discovery of potential 5α-reductase phytochemical inhibitors and hair growth promotion using in silico techniques. doi:10.3389/fbinf.2025.1570101 PubMed
- [5] David Broadley et al.. Int J Cosmet Sci. 2025. A proprietary lipidosterolic extract of Serenoa repens promotes hair growth through mechanisms that extend beyond 5-alpha reductase inhibition: Insights from … doi:10.1111/ics.70035 PubMed
- [6] Massimo Milani et al.. J Cosmet Dermatol. 2025. Impact of a Novel Dietary Supplement on Efficacy of Pharmacological Treatments for Androgenic Alopecia: A Real-Life, Multicenter, Randomized, Assessor-Blinded Trial … doi:10.1111/jocd.70388 PubMed
- [7] Aditya K Gupta et al.. Skin Appendage Disord. 2025. Do Non-Prescription Products Help in Managing Androgenic Alopecia? doi:10.1159/000542880 PubMed
- [8] Adam Leavitt et al.. J Drugs Dermatol. 2025. Addressing the Root Causes of Female Hair Loss and Non-Pharmaceutical Interventions. doi:10.36849/JDD.8763 PubMed
- [9] Lei Zhou et al.. Front Nutr. 2025. Effects of dietary supplements on androgenetic alopecia: a systematic review and network meta-analysis. doi:10.3389/fnut.2025.1719711 PubMed
- [10] Promise Ufomadu. Proc (Bayl Univ Med Cent). 2024. Complementary and alternative supplements: a review of dermatologic effectiveness for androgenetic alopecia. doi:10.1080/08998280.2023.2263829 PubMed
- [11] Aditya K Gupta et al.. Expert Opin Emerg Drugs. 2024. Emerging and traditional 5-α reductase inhibitors and androgen receptor antagonists for male androgenetic alopecia. doi:10.1080/14728214.2024.2346590 PubMed
- [12] Nouf F Bin Rubaian et al.. Clin Cosmet Investig Dermatol. 2024. An Overview of Commonly Used Natural Alternatives for the Treatment of Androgenetic Alopecia, with Special Emphasis on Rosemary Oil. doi:10.2147/CCID.S470989 PubMed
- [13] Pavithra Tr et al.. Cureus. 2023. A Comparative Study of Topical Procapil With Platelet-Rich Plasma Therapy Versus Topical Redensyl, Saw Palmetto, and Biotin With Platelet-Rich Plasma … doi:10.7759/cureus.38696 PubMed
- [14] Jeffrey Rapaport et al.. J Drugs Dermatol. 2023. Real-World, Open-Label Study of the Efficacy and Safety of a Novel Serum in Androgenetic Alopecia. doi:10.36849/JDD.7403 PubMed
- [15] Heggar Venkataramana Sudeep et al.. Clin Cosmet Investig Dermatol. 2023. Oral and Topical Administration of a Standardized Saw Palmetto Oil Reduces Hair Fall and Improves the Hair Growth in Androgenetic … doi:10.2147/CCID.S435795 PubMed
- [16] Aditya K Gupta et al.. Dermatol Ther. 2022. Natural products for male androgenetic alopecia. doi:10.1111/dth.15323 PubMed
- [17] Katherine York et al.. Expert Opin Pharmacother. 2020. A review of the treatment of male pattern hair loss. doi:10.1080/14656566.2020.1721463 PubMed
- [18] Ana Zgonc Škulj et al.. Arch Dermatol Res. 2020. Herbal preparations for the treatment of hair loss. doi:10.1007/s00403-019-02003-x PubMed
- [19] Evyatar Evron et al.. Skin Appendage Disord. 2020. Natural Hair Supplement: Friend or Foe? Saw Palmetto, a Systematic Review in Alopecia. doi:10.1159/000509905 PubMed
- [20] Maria Yusuf Dhariwala et al.. J Cosmet Dermatol. 2019. An overview of herbal alternatives in androgenetic alopecia. doi:10.1111/jocd.12930 PubMed
- [21] A Rossi et al.. Int J Immunopathol Pharmacol. 2012. Comparitive effectiveness of finasteride vs Serenoa repens in male androgenetic alopecia: a two-year study. doi:10.1177/039463201202500435 PubMed
- [22] Sridar Chittur et al.. Evid Based Complement Alternat Med. 2011. Inhibition of inflammatory gene expression in keratinocytes using a composition containing carnitine, thioctic Acid and saw palmetto extract. doi:10.1093/ecam/nep102 PubMed
- [23] Rodney D Sinclair et al.. Australas J Dermatol. 2002. Sensitization to saw palmetto and minoxidil in separate topical extemporaneous treatments for androgenetic alopecia. doi:10.1046/j.1440-0960.2002.00620.x PubMed
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