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ノコギリヤシ 男性型・女性型脱毛症(AGA)

A

合計2,123名の参加者を対象とした21件の研究(メタアナリシス2件、RCT 4件を含む)に基づく。21件中20件の研究で肯定的な効果が示されている。

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A

結論

Saw palmetto is well-supported by clinical research as a natural supplement that may help slow hair loss and support regrowth in androgenetic alopecia by naturally inhibiting DHT production.

  • 95% of studies (20/21) show positive effects, including 4 RCTs and 2 meta-analyses
  • Works as a natural 5-alpha reductase inhibitor, reducing DHT levels
  • Both oral supplementation and topical application have demonstrated benefits
  • Generally well-tolerated, though less potent than prescription finasteride

Key Study Findings

RCT n=80 24 weeks Double-blind
Oral Supplementation with l-Cystine, Serenoa repens, Cucurbita pepo, and Pygeum africanum in Chronic Telogen Effluvium …
Dose: 1 capsule daily (l-Cystine, Serenoa repens, Cucurbita pepo, Pygeum africanum, vitamins, micronutrien vs: Placebo 効果: MD=+12.3 hairs/cm2 at 6 months p<0.05
narrative review
Addressing the Root Causes of Female Hair Loss and Non-Pharmaceutical Interventions.
Dose: None vs: Placebo 効果: None None
narrative review
Herbal Remedies for Hair Loss: A Review of Efficacy and Safety.
Dose: varies by remedy and study vs: Placebo 効果: None None
systematic review n=1658 Double-blind
Effects of dietary supplements on androgenetic alopecia: a systematic review and network meta-analysis.
Dose: various dietary supplements (Nutrafol, apple extract, tocotrienols, pumpkin seed oil, Cistanche/Lami vs: Placebo 効果: None None
review Single-blind
Do Non-Prescription Products Help in Managing Androgenic Alopecia?
Dose: Various non-prescription agents: procyanidin, cetirizine, caffeine, Oryza sativa bran, pumpkin seed vs: Placebo 効果: Considerable improvements in one or more parameters across 13 included studies None

Key Statistics

22

研究数

2123

参加者数

Positive

A

グレード

Referenced Papers

Skin appendage disorders 2025 7 件の引用
Skin appendage disorders 2025 1 件の引用
Dermatologic therapy 2022 41 件の引用
Expert opinion on … 2020 147 件の引用
Archives of dermatological … 2020 51 件の引用
Journal of cosmetic … 2019 100 件の引用

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

一般的な使用量

general:
320 mg/day
hairloss:
320 mg/day standardized extract

上限量: Not established

研究で検討された用量

用量 期間 効果 N
None -- Neutral --
1 capsule daily (l-Cystine, Serenoa repens, Cucurbita pepo, Pygeum africanum, vitamins, micronutrien 24 weeks Positive 80
None -- Positive --
varies by remedy and study -- Positive --
various dietary supplements (Nutrafol, apple extract, tocotrienols, pumpkin seed oil, Cistanche/Lami -- Positive 1658
Various non-prescription agents: procyanidin, cetirizine, caffeine, Oryza sativa bran, pumpkin seed -- Positive --
None -- Positive --
USPlus DERM (lipidosterolic extract of Serenoa repens) at 0.4 and 10 μg/mL in hair follicle organ cu -- Positive --

推奨摂取タイミング: With meals to reduce gastrointestinal side effects

Safety & Side Effects

報告されている副作用

  • Mild gastrointestinal upset (nausea, diarrhea)
  • Headache
  • Dizziness
  • Rare: decreased libido

既知の相互作用

  • Anticoagulants and antiplatelet drugs (may increase bleeding risk)
  • Oral contraceptives and hormone replacement therapy (anti-androgenic effects)
  • Finasteride and dutasteride (additive 5-alpha-reductase inhibition)

耐容上限摂取量: Not established

サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。

Frequently Asked Questions

Does ノコギリヤシ help with 男性型・女性型脱毛症(AGA)?
Based on 22 studies with 2,123 participants, there is strong evidence from multiple clinical trials that ノコギリヤシ may support 男性型・女性型脱毛症(AGA) management. Our evidence grade is A (Strong Evidence).
How much ノコギリヤシ should I take for 男性型・女性型脱毛症(AGA)?
Studies have used various dosages. A commonly studied range is 320 mg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of ノコギリヤシ?
Reported side effects may include Mild gastrointestinal upset (nausea, diarrhea), Headache, Dizziness, Rare: decreased libido. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for ノコギリヤシ and 男性型・女性型脱毛症(AGA)?
We rate the evidence as Grade A (Strong Evidence). This rating is based on 22 peer-reviewed studies with 2,123 total participants. The overall direction of effect is positive.

Related Evidence

ノコギリヤシ 他の症状・状態について

FDAに関する免責事項: これらの記述は米国食品医薬品局(FDA)による評価を受けていません。本ウェブサイトの製品および情報は、疾病の診断、治療、治癒、または予防を目的としたものではありません。表示されているエビデンスグレードは、公開された査読済み研究の分析に基づいており、医療上の助言を構成するものではありません。サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。