Spironolattone per Alopecia androgenetica
A Evidenze Più grandi trial clinici mostrano in modo costante benefici significativi.Basato su 25 studi (4 meta-analyses, 2 RCTs) con 6,273 partecipanti totali. 19/25 studi mostrano effetti positivi.
In sintesi
Spironolactone is well-supported by research as an anti-androgen medication that may help reduce hair loss in androgenetic alopecia, particularly in women, though it requires medical supervision.
- 76% of studies show positive effects, backed by 4 meta-analyses
- Works by blocking androgen hormones that contribute to hair miniaturization
- Particularly studied in women with PCOS-related and female pattern hair loss
- Requires prescription and medical monitoring due to hormonal effects
Key Study Findings
Popolazione: women with androgenetic alopecia (female pattern hair loss)
Popolazione: Individuals with insomnia
Popolazione: Pediatric patients with androgenetic alopecia (multicenter)
Popolazione: Patients with androgenetic alopecia
Key Statistics
45
Studi
6472
Partecipanti
Positive
Grado
Referenced Papers
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
Dosaggi di uso comune
- hairloss:
- 100-200 mg/day (prescription)
Limite massimo: 200 mg/day (hair loss indication)
Dosaggi studiati nella ricerca
| Dosaggio | Durata | Effetto | N |
|---|---|---|---|
| None | -- | Neutral | -- |
| None | -- | Positive | -- |
| Spironolactone 100 mg once daily | 24 weeks | Positive | 48 |
| CBD 300 mg + 1 mg each of 8 terpenes | 4 weeks | Positive | 125 |
| None | -- | Positive | 203 |
| None | -- | Positive | 30 |
| various across included studies (2015-2024) | -- | Positive | -- |
| None | -- | Mixed | -- |
Momento migliore per l'assunzione: Once or twice daily with food; prescription required
Safety & Side Effects
Effetti collaterali segnalati
- ⚠ Menstrual irregularities
- ⚠ Breast tenderness
- ⚠ Hyperkalemia (elevated potassium levels)
- ⚠ Dizziness and orthostatic hypotension
- ⚠ Frequent urination
Interazioni note
- ● ACE inhibitors and ARBs (increased hyperkalemia risk)
- ● Potassium supplements and potassium-sparing diuretics (dangerous hyperkalemia)
- ● NSAIDs (may reduce diuretic effectiveness and increase kidney risk)
- ● Digoxin (spironolactone may increase digoxin levels)
Livello di assunzione massimo tollerabile: 200 mg/day (hair loss indication)
Consultare sempre il proprio medico prima di iniziare qualsiasi integratore.Consultate sempre il vostro medico prima di iniziare qualsiasi integratore.
Frequently Asked Questions
Does Spironolattone help with Alopecia androgenetica?
How much Spironolattone should I take for Alopecia androgenetica?
Are there side effects of Spironolattone?
How strong is the evidence for Spironolattone and Alopecia androgenetica?
Related Evidence
Altri ingredienti per Alopecia androgenetica
Spironolattone per altre condizioni
References
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