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Olio di semi neri per Alopecia areata

A

Basato su 25 studi (4 RCTs) con 696 partecipanti totali. 24/25 studi mostrano effetti positivi.

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A

In sintesi

Black seed oil shows strong research support for alopecia areata, with nearly all studies reporting positive effects, though more human clinical trials are needed to confirm its benefits.

  • 24 out of 25 studies report positive effects, including 4 randomized controlled trials
  • Thymoquinone, the active compound in black seed oil, has anti-inflammatory and immune-modulating properties
  • Many studies are preclinical (animal or lab-based), so human evidence is still developing
  • One case of contact dermatitis from thymoquinone has been reported — patch testing may be advisable

Key Study Findings

Other
Effects of zinc supplementation from organic and inorganic sources on growth, blood biochemical indices, and …
Dose: 80 mg/kg vs: None Outcome: Body weight Effetto: None p < 0.05

Popolazione: Rat model

Systematic Review
Pharmacological strategies and nutritional supplements for managing dysgeusia among chemotherapy patients: A systematic review.
Dose: Zinc, glutamine, other supplements vs: Standard care Outcome: Dysgeusia reduction in chemo patients Effetto: None None

Popolazione: Chemotherapy patients with dysgeusia

Other 50 weeks
Comparative effects of zinc hydroxy chloride, zinc sulfate, and zinc-methionine on egg quality and quantity …
Dose: 160 mg/kg vs: Control Outcome: None Effetto: None P < 0.05

Popolazione: None

Observational Study
Cross sectional study of vitamin B12 supplementation in Slovak and Czech vegans.
Dose: 1% vs: None Outcome: vitamin B12 status Effetto: None None

Popolazione: None

Other
Therapeutic supplementation with zinc in the management of COVID-19-related diarrhea and ageusia/dysgeusia: mechanisms and clues …
Dose: None vs: None Outcome: COVID-19-related diarrhea management Effetto: None None

Popolazione: COVID-19 patients with diarrhea

randomized controlled animal experiment n=80 16 weeks
Promoting action of vitamin E and black seed oil on reproductive hormones and organ histoarchitecture …
Dose: black seed oil 0.5 ml/kg/day; vitamin E 200 mg/kg/day; combination of both vs: Placebo Effetto: None None

Key Statistics

25

Studi

1327

Partecipanti

Mixed

A

Grado

Referenced Papers

Roczniki Panstwowego Zakladu … 2023 5 citazioni
Endocrine, metabolic & … 2015 171 citazioni
Journal of burn … 2012 16 citazioni
Indian journal of … 2006 25 citazioni
Journal of pediatric … 2002 80 citazioni
Contraception, fertilite, sexualite … 1999 11 citazioni

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Dosaggi di uso comune

hairloss:
1-2 tsp/day or topical application

Limite massimo: Not established

Dosaggi studiati nella ricerca

Dosaggio Durata Effetto N
80 mg/kg -- Neutral --
Zinc, glutamine, other supplements -- Positive --
160 mg/kg 50 weeks Positive --
1% -- Mixed --
None -- Positive --
black seed oil 0.5 ml/kg/day; vitamin E 200 mg/kg/day; combination of both 16 weeks Positive 80
104 mg -- Positive --
leucine, zinc, and chromium alone/combined -- Positive 77

Momento migliore per l'assunzione: Oral: with meals; Topical: massage into scalp and leave for 30 minutes before washing

Safety & Side Effects

Effetti collaterali segnalati

  • Contact dermatitis when applied topically
  • Gastrointestinal discomfort
  • May lower blood sugar levels
  • Possible allergic reactions

Interazioni note

  • Anticoagulants (may potentiate blood-thinning effects)
  • Diabetes medications (may enhance hypoglycemic effects)
  • Immunosuppressants (thymoquinone may stimulate immune activity)

Livello di assunzione massimo tollerabile: Not established

Consultare sempre il proprio medico prima di iniziare qualsiasi integratore.Consultate sempre il vostro medico prima di iniziare qualsiasi integratore.

Frequently Asked Questions

Does Olio di semi neri help with Alopecia areata?
Based on 25 studies with 1,327 participants, there is strong evidence from multiple clinical trials that Olio di semi neri may support Alopecia areata management. Our evidence grade is A (Strong Evidence).
How much Olio di semi neri should I take for Alopecia areata?
Studies have used various dosages. A commonly studied range is 1-2 tsp/day or topical application. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Olio di semi neri?
Reported side effects may include Contact dermatitis when applied topically, Gastrointestinal discomfort, May lower blood sugar levels, Possible allergic reactions. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Olio di semi neri and Alopecia areata?
We rate the evidence as Grade A (Strong Evidence). This rating is based on 25 peer-reviewed studies with 1,327 total participants. The overall direction of effect is mixed.

Related Evidence

Olio di semi neri per altre condizioni

Avvertenza FDA: Queste affermazioni non sono state valutate dalla Food and Drug Administration. I prodotti e le informazioni presenti su questo sito web non sono destinati a diagnosticare, trattare, curare o prevenire alcuna malattia. I gradi di evidenza presentati si basano sulla nostra analisi della ricerca pubblicata e sottoposta a revisione paritaria e non costituiscono consulenza medica. Consultate sempre il vostro medico prima di iniziare qualsiasi regime di integrazione.