Spironolactone के लिए Androgenetic Alopecia

25 अध्ययनों (4 meta-analyses, 2 RCTs) पर आधारित, में कुल 6,273 प्रतिभागियों के साथ। 19/25 अध्ययन सकारात्मक प्रभाव दिखाते हैं।

𝕏 LinkedIn

<\/script>\n

`; }, get iframeSnippet() { const domain = 'haircited.com'; const params = 'ingredient\u003Dspironolactone\u0026condition\u003Dandrogenetic\u002Dalopecia'; return ``; }, get activeSnippet() { return this.method === 'script' ? this.scriptSnippet : this.iframeSnippet; }, copySnippet() { navigator.clipboard.writeText(this.activeSnippet).then(() => { this.copied = true; setTimeout(() => { this.copied = false; }, 2000); }); } }" @keydown.escape.window="open = false" @click.outside="open = false">

Embed This Widget

Style

Widget powered by . Free, no account required.

निष्कर्ष

Spironolactone is well-supported by research as an anti-androgen medication that may help reduce hair loss in androgenetic alopecia, particularly in women, though it requires medical supervision.

76% of studies show positive effects, backed by 4 meta-analyses
Works by blocking androgen hormones that contribute to hair miniaturization
Particularly studied in women with PCOS-related and female pattern hair loss
Requires prescription and medical monitoring due to hormonal effects

Key Study Findings

Review

Androgenetic Alopecia in Women: A Narrative Review of Pathophysiology, Clinical Evaluation, and Treatments.

Dose: None बनाम: None Outcome: None प्रभाव: None None

जनसंख्या: women with androgenetic alopecia (female pattern hair loss)

Review

Male and female pattern hair loss.

Dose: None बनाम: Placebo प्रभाव: None None

RCT n=48 24 weeks Double-blind

Efficacy and safety of oral spironolactone for female pattern hair loss in premenopausal women: a …

Dose: Spironolactone 100 mg once daily बनाम: Placebo प्रभाव: Terminal hair counts: 9.48 vs 5.32 hairs/cm2; hair diameter: 4.23 vs 2.96 μm; moderate-to-marked imp p=0.063 (terminal hair counts)

Randomized Controlled Trial n=125 4 weeks Double-blind

Effects of a cannabidiol/terpene formulation on sleep in individuals with insomnia: a double-blind, placebo-controlled, randomized, …

Dose: CBD 300 mg + 1 mg each of 8 terpenes बनाम: Placebo Outcome: Percentage of time in SWS + REM sleep प्रभाव: 1.3% increase [0.1-2.5%]; up to 48 min/night in su 0.03

जनसंख्या: Individuals with insomnia

Cohort Study n=203

An international multicenter, retrospective cohort study of 203 patients with pediatric androgenetic alopecia.

Dose: None बनाम: None Outcome: Clinical presentation and treatment outcomes in pediatric AGA प्रभाव: None None

जनसंख्या: Pediatric patients with androgenetic alopecia (multicenter)

Randomized Controlled Trial n=30

A Prospective and Comparative Study to Explore the Effects of Platelet-Rich Plasma in Hair Transplantation …

Dose: None बनाम: Drug therapy (minoxidil + finasteride/spironolactone) only Outcome: Follicle survival rate, growth rate, hair strength प्रभाव: None None

जनसंख्या: Patients with androgenetic alopecia

Key Statistics

अध्ययन

6472

प्रतिभागी

↑

Positive

ग्रेड

Referenced Papers

Androgenetic Alopecia in Women: A Narrative Review of Pathophysiology, Clinical Evaluation, and Treatments. Review

American journal of … 2026

Efficacy, safety and tolerability of drugs for alopecia: a comprehensive review. Review

Expert opinion on … 2025 11 उद्धरण

Nutritional deficiencies after sleeve gastrectomy and Roux-en-Y gastric bypass at 10 years: secondary analysis of the SLEEVEPASS randomized clinical trial. RCT

The British journal … 2025 10 उद्धरण

Epidemiological landscape of androgenetic alopecia in the US: An All of Us cross-sectional study. Other

PloS one 2025 8 उद्धरण

A Scoping Review of Exosome Delivery Applications in Hair Loss. Review

Cureus 2025 7 उद्धरण

Effects of a cannabidiol/terpene formulation on sleep in individuals with insomnia: a double-blind, placebo-controlled, randomized, crossover study. RCT

Journal of clinical … 2025 6 उद्धरण

A Prospective and Comparative Study to Explore the Effects of Platelet-Rich Plasma in Hair Transplantation for Patients With Androgenetic Alopecia. RCT

Journal of cosmetic … 2025 5 उद्धरण

Efficacy and safety of oral spironolactone for female pattern hair loss in premenopausal women: a randomized, double-blind, placebo-controlled, parallel-group pilot … Other

International journal of … 2025 3 उद्धरण

An international multicenter, retrospective cohort study of 203 patients with pediatric androgenetic alopecia. Other

Journal of the … 2025 3 उद्धरण

Non-classical congenital adrenal hyperplasia: current insights into clinical implications, diagnosis and treatment. Review

Endocrine 2025 2 उद्धरण

Male and female pattern hair loss. Review

Australian prescriber 2025 2 उद्धरण

Estrogen hormone therapy stabilizes lateral hairline in transfeminine patients: Implications for facial feminization surgery. Other

Journal of plastic, … 2025 1 उद्धरण

Evaluating the Role of the Gabrin Sign in Predicting COVID-19 Severity Among Patients with Androgenic Alopecia. Other

International journal of … 2025

The Hormonal Background of Hair Loss in Non-Scarring Alopecias. Review

Biomedicines 2024 17 उद्धरण

The efficacy of the combination of topical minoxidil and oral spironolactone compared with the combination of topical minoxidil and oral … RCT

Journal of cosmetic … 2024 14 उद्धरण

Management of androgenic alopecia: a systematic review of the literature. Systematic Review

Journal of cosmetic … 2024 11 उद्धरण

Safety of Antiandrogens for the Treatment of Female Androgenetic Alopecia with Respect to Gynecologic Malignancies. Review

Journal of clinical … 2024 11 उद्धरण

Cannabidiol (CBD) Inhibits Foam Cell Formation via Regulating Cholesterol Homeostasis and Lipid Metabolism. Other

Molecular nutrition & … 2024 5 उद्धरण

Comparative analysis of low-dose oral minoxidil with spironolactone versus finasteride or dutasteride in female androgenetic alopecia management. Other

Archives of dermatological … 2024 4 उद्धरण

Improving efficacy and maintaining safety in the treatment of alopecia with low-dose oral minoxidil and spironolactone combination therapy: A retrospective … Other

JAAD international 2024 1 उद्धरण

Potential of dietary hemp and cannabinoids to modulate immune response to enhance health and performance in animals: opportunities and challenges. Review

Frontiers in immunology 2023 99 उद्धरण

Androgenetic alopecia: An update. Review

JAAD international 2023 80 उद्धरण

Treatment of Androgenetic Alopecia: Current Guidance and Unmet Needs. Review

Clinical, cosmetic and … 2023 58 उद्धरण

The Efficacy and Safety of Oral and Topical Spironolactone in Androgenetic Alopecia Treatment: A Systematic Review. Review

Clinical, cosmetic and … 2023 25 उद्धरण

Androgenetic alopecia in transgender and gender diverse populations: A review of therapeutics. Review

Journal of the … 2023 24 उद्धरण

Medical and procedural treatment of androgenetic alopecia - Where are we? Review

Journal of the … 2023 20 उद्धरण

The Efficacy and Safety of Oral Spironolactone in the Treatment of Female Pattern Hair Loss: A Systematic Review and Meta-Analysis. Review

Cureus 2023 13 उद्धरण

Efficacy and safety profile of oral spironolactone use for androgenic alopecia: A systematic review. Systematic Review

Journal of the … 2022 24 उद्धरण

Efficacy and Safety of 5% Minoxidil Alone, Minoxidil Plus Oral Spironolactone, and Minoxidil Plus Microneedling on Female Pattern Hair Loss: … Case Report

Frontiers in medicine 2022 14 उद्धरण

Primary care provider attitudes, experiences and practices about cannabidiol (CBD) and barriers to patient-provider communication about CBD use: A qualitative … Other

PEC innovation 2022 11 उद्धरण

Observation on the Efficacy of a Combined Treatment for Moderate and Severe Androgenetic Alopecia Incorporating Electric Microneedles. Other

Clinical, cosmetic and … 2022 3 उद्धरण

The Role of Cannabidiol (CBD) in Chronic Pain Management: An Assessment of Current Evidence. Review

Current pain and … 2020 85 उद्धरण

Spironolactone use does not increase the risk of female breast cancer recurrence: A retrospective analysis. Other

Journal of the … 2020 19 उद्धरण

Herbal Medicines For Treatment of Androgenic Alopecia. Review

Alternative therapies in … 2020 11 उद्धरण

Female Pattern Hair Loss and Androgen Excess: A Report From the Multidisciplinary Androgen Excess and PCOS Committee. Meta-Analysis

The Journal of … 2019 101 उद्धरण

Androgens in women: Androgen-mediated skin disease and patient evaluation. Review

Journal of the … 2019 95 उद्धरण

Androgens in women: Hormone-modulating therapies for skin disease. Review

Journal of the … 2019 55 उद्धरण

Methods of treatment patients with androgenetic alopecia based on reference of Department of Dermatology in Cracow. Other

Polski merkuriusz lekarski … 2019 4 उद्धरण

Female pattern hair loss: A clinical, pathophysiologic, and therapeutic review. Review

International journal of … 2018 129 उद्धरण

Prescribing Habits for Androgenic Alopecia Among Dermatologists in Spain in 2017: A Cross-Sectional Study. Other

Actas dermo-sifiliograficas 2018 9 उद्धरण

Androgenic alopecia: an entity to consider in adolescence. Case Report

BMJ case reports 2017 6 उद्धरण

Interventions for female pattern hair loss. Meta-Analysis

The Cochrane database … 2016 18 उद्धरण

Selected Disorders of Skin Appendages--Acne, Alopecia, Hyperhidrosis. Review

The Medical clinics … 2015 66 उद्धरण

Evidence-based approach to cutaneous hyperandrogenism in women. Review

Journal of the … 2015 50 उद्धरण

Female pattern hair loss. Review

Current problems in … 2015 8 उद्धरण

Follicular delivery of spironolactone via nanostructured lipid carriers for management of alopecia. Other

International journal of … 2014 113 उद्धरण

Female pattern alopecia: current perspectives. Review

International journal of … 2013

Hair loss in women: medical and cosmetic approaches to increase scalp hair fullness. Review

The British journal … 2011 96 उद्धरण

Innovative use of spironolactone as an antiandrogen in the treatment of female pattern hair loss. Other

Dermatologic clinics 2010 80 उद्धरण

Hormonal therapy for acne: why not as first line therapy? facts and controversies. Review

Clinics in dermatology 2010

Hair loss in women. Review

Seminars in cutaneous … 2009 4 उद्धरण

A review of hormonal therapy for female pattern (androgenic) alopecia. Review

Dermatology online journal 2008

Treatment of female pattern hair loss with a combination of spironolactone and minoxidil. Case Report

The Australasian journal … 2007 32 उद्धरण

Association of androgenetic alopecia and hypertension. Other

European journal of … 2007

[Androgenetic alopecia]. Review

Revue medicale de … 2004

Practical recommendations for the use of ACE inhibitors, beta-blockers and spironolactone in heart failure: putting guidelines into practice. Other

European journal of … 2001 67 उद्धरण

Current aspects of antiandrogen therapy in women. Review

Current pharmaceutical design 1999

Management of androgenetic alopecia. Review

Journal of the … 1999

Hair regrowth. Therapeutic agents. Review

Dermatologic clinics 1998 121 उद्धरण

Beneficial effect of spironolactone on androgenic alopecia. Other

Clinical endocrinology 1997

Treatment of androgenic disorders with dexamethasone: dose-response relationship for suppression of dehydroepiandrosterone sulfate. Other

Journal of the … 1990

Oral spironolactone therapy for female patients with acne, hirsutism or androgenic alopecia. Other

The British journal … 1985

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

सामान्य रूप से उपयोग की जाने वाली खुराकें

hairloss:: 100-200 mg/day (prescription)

अधिकतम सीमा: 200 mg/day (hair loss indication)

अनुसंधान में अध्ययन की गई खुराकें

खुराक	अवधि	प्रभाव	N
None	--	Neutral	--
None	--	Positive	--
Spironolactone 100 mg once daily	24 weeks	Positive	48
CBD 300 mg + 1 mg each of 8 terpenes	4 weeks	Positive	125
None	--	Positive	203
None	--	Positive	30
various across included studies (2015-2024)	--	Positive	--
None	--	Mixed	--

सेवन का सर्वोत्तम समय: Once or twice daily with food; prescription required

Safety & Side Effects

रिपोर्ट किए गए दुष्प्रभाव

⚠ Menstrual irregularities
⚠ Breast tenderness
⚠ Hyperkalemia (elevated potassium levels)
⚠ Dizziness and orthostatic hypotension
⚠ Frequent urination

ज्ञात अंतःक्रियाएँ

● ACE inhibitors and ARBs (increased hyperkalemia risk)
● Potassium supplements and potassium-sparing diuretics (dangerous hyperkalemia)
● NSAIDs (may reduce diuretic effectiveness and increase kidney risk)
● Digoxin (spironolactone may increase digoxin levels)

सहनीय अधिकतम सेवन: 200 mg/day (hair loss indication)

कोई भी सप्लीमेंट शुरू करने से पहले हमेशा अपने स्वास्थ्य सेवा प्रदाता से परामर्श करें।

Frequently Asked Questions

Does Spironolactone help with Androgenetic Alopecia?

Based on 45 studies with 6,472 participants, there is strong evidence from multiple clinical trials that Spironolactone may support Androgenetic Alopecia management. Our evidence grade is A (Strong Evidence).

How much Spironolactone should I take for Androgenetic Alopecia?

Studies have used various dosages. A commonly studied range is 100-200 mg/day (prescription). Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Spironolactone?

Reported side effects may include Menstrual irregularities, Breast tenderness, Hyperkalemia (elevated potassium levels), Dizziness and orthostatic hypotension. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Spironolactone and Androgenetic Alopecia?

We rate the evidence as Grade A (Strong Evidence). This rating is based on 45 peer-reviewed studies with 6,472 total participants. The overall direction of effect is positive.

Related Evidence

इसके लिए अन्य सामग्री Androgenetic Alopecia

Minoxidil A Finasteride A PRP Therapy A Dutasteride A Omega-3 Fatty Acids A Microneedling A

Spironolactone अन्य स्वास्थ्य स्थितियों के लिए

महिला पैटर्न बाल झड़ना A

संक्षिप्त निष्कर्ष

Evidence Strength92%

High confidence

अध्ययन विश्लेषण

RCT (4)Meta (2)Other (39)

विकल्पों की तुलना करें

देखें कि इस स्वास्थ्य स्थिति के लिए अन्य सामग्री की तुलना कैसे है।

इसके लिए सभी सामग्री देखें Androgenetic Alopecia

अधिक जानें

FDA अस्वीकरण: इन कथनों का Food and Drug Administration द्वारा मूल्यांकन नहीं किया गया है। इस वेबसाइट पर उत्पादों और जानकारी का उद्देश्य किसी बीमारी का निदान, उपचार, इलाज या रोकथाम नहीं है। प्रस्तुत साक्ष्य ग्रेड प्रकाशित पीयर-रिव्यूड अनुसंधान के हमारे विश्लेषण पर आधारित हैं और चिकित्सा सलाह नहीं हैं। कोई भी सप्लीमेंट शुरू करने से पहले हमेशा अपने स्वास्थ्य सेवा प्रदाता से परामर्श करें।