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Huile de nigelle pour Alopecia Areata

A

Basé sur 25 études (4 RCTs) avec 696 participants au total. 24/25 études montrent des effets positifs.

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A

En conclusion

Black seed oil shows strong research support for alopecia areata, with nearly all studies reporting positive effects, though more human clinical trials are needed to confirm its benefits.

  • 24 out of 25 studies report positive effects, including 4 randomized controlled trials
  • Thymoquinone, the active compound in black seed oil, has anti-inflammatory and immune-modulating properties
  • Many studies are preclinical (animal or lab-based), so human evidence is still developing
  • One case of contact dermatitis from thymoquinone has been reported — patch testing may be advisable

Key Study Findings

Other
Effects of zinc supplementation from organic and inorganic sources on growth, blood biochemical indices, and …
Dose: 80 mg/kg vs: None Outcome: Body weight Effet: None p < 0.05

Population: Rat model

Systematic Review
Pharmacological strategies and nutritional supplements for managing dysgeusia among chemotherapy patients: A systematic review.
Dose: Zinc, glutamine, other supplements vs: Standard care Outcome: Dysgeusia reduction in chemo patients Effet: None None

Population: Chemotherapy patients with dysgeusia

Other 50 weeks
Comparative effects of zinc hydroxy chloride, zinc sulfate, and zinc-methionine on egg quality and quantity …
Dose: 160 mg/kg vs: Control Outcome: None Effet: None P < 0.05

Population: None

Observational Study
Cross sectional study of vitamin B12 supplementation in Slovak and Czech vegans.
Dose: 1% vs: None Outcome: vitamin B12 status Effet: None None

Population: None

Other
Therapeutic supplementation with zinc in the management of COVID-19-related diarrhea and ageusia/dysgeusia: mechanisms and clues …
Dose: None vs: None Outcome: COVID-19-related diarrhea management Effet: None None

Population: COVID-19 patients with diarrhea

randomized controlled animal experiment n=80 16 weeks
Promoting action of vitamin E and black seed oil on reproductive hormones and organ histoarchitecture …
Dose: black seed oil 0.5 ml/kg/day; vitamin E 200 mg/kg/day; combination of both vs: Placebo Effet: None None

Key Statistics

25

Études

1327

Participants

Mixed

A

Note

Referenced Papers

Roczniki Panstwowego Zakladu … 2023 5 citations
Endocrine, metabolic & … 2015 171 citations
Journal of burn … 2012 16 citations
Indian journal of … 2006 25 citations
Journal of pediatric … 2002 80 citations
Contraception, fertilite, sexualite … 1999 11 citations

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Posologies couramment utilisées

hairloss:
1-2 tsp/day or topical application

Limite supérieure : Not established

Posologies étudiées dans la recherche

Posologie Durée Effet N
80 mg/kg -- Neutral --
Zinc, glutamine, other supplements -- Positive --
160 mg/kg 50 weeks Positive --
1% -- Mixed --
None -- Positive --
black seed oil 0.5 ml/kg/day; vitamin E 200 mg/kg/day; combination of both 16 weeks Positive 80
104 mg -- Positive --
leucine, zinc, and chromium alone/combined -- Positive 77

Moment optimal de prise : Oral: with meals; Topical: massage into scalp and leave for 30 minutes before washing

Safety & Side Effects

Effets indésirables signalés

  • Contact dermatitis when applied topically
  • Gastrointestinal discomfort
  • May lower blood sugar levels
  • Possible allergic reactions

Interactions connues

  • Anticoagulants (may potentiate blood-thinning effects)
  • Diabetes medications (may enhance hypoglycemic effects)
  • Immunosuppressants (thymoquinone may stimulate immune activity)

Apport maximal tolérable : Not established

Consultez toujours votre professionnel de santé avant de commencer tout complément alimentaire.Consultez toujours votre professionnel de santé avant de commencer tout complément alimentaire.

Frequently Asked Questions

Does Huile de nigelle help with Alopecia Areata?
Based on 25 studies with 1,327 participants, there is strong evidence from multiple clinical trials that Huile de nigelle may support Alopecia Areata management. Our evidence grade is A (Strong Evidence).
How much Huile de nigelle should I take for Alopecia Areata?
Studies have used various dosages. A commonly studied range is 1-2 tsp/day or topical application. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Huile de nigelle?
Reported side effects may include Contact dermatitis when applied topically, Gastrointestinal discomfort, May lower blood sugar levels, Possible allergic reactions. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Huile de nigelle and Alopecia Areata?
We rate the evidence as Grade A (Strong Evidence). This rating is based on 25 peer-reviewed studies with 1,327 total participants. The overall direction of effect is mixed.

Related Evidence

Huile de nigelle pour d'autres pathologies

Avertissement FDA: Ces déclarations n'ont pas été évaluées par la Food and Drug Administration. Les produits et informations sur ce site ne sont pas destinés à diagnostiquer, traiter, guérir ou prévenir quelque maladie que ce soit. Les notes de preuve présentées sont basées sur notre analyse de la recherche publiée et évaluée par des pairs et ne constituent pas un avis médical. Consultez toujours votre professionnel de santé avant de commencer tout régime de compléments alimentaires.