Витамин D для Alopecia Areata
A Доказательства Несколько крупных клинических испытаний стабильно демонстрируют значительные преимущества.На основе 62 исследований (8 meta-analyses, 1 RCT) с участием 9,085,485 участников. Большинство исследований не показывают значимых эффектов.
Итог
While people with alopecia areata often have lower vitamin D levels, research suggests that vitamin D supplementation alone does not reliably help with this condition.
- 62 studies confirm an association between low vitamin D and alopecia areata
- Multiple meta-analyses find correlation but not causation
- Supplementation has not shown consistent benefits for hair regrowth in alopecia areata
- Low vitamin D may be a marker of autoimmune activity rather than a cause of hair loss
Key Study Findings
Популяция: Alopecia areata patients vs healthy controls
Популяция: 36 AA patients vs 36 matched controls, mean age 39
Key Statistics
98
Исследования
9086791
Участники
Mixed
Оценка
Referenced Papers
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
Часто используемые дозировки
- general:
- 600-800 IU/day
- deficiency:
- 1,000-5,000 IU/day
Верхний предел: 4,000 IU/day
Дозировки, изученные в исследованиях
| Дозировка | Длительность | Эффект | N |
|---|---|---|---|
| Topical or intralesional vitamin D3 and analogs (various doses and formulations) | -- | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Negative | 4931 |
| None | -- | Positive | -- |
| None | -- | Positive | 144 |
| None | -- | Negative | 72 |
| Topical ointment application (3 arms) | 8 weeks | Positive | -- |
| oral betamethasone 2 mg (children) or 4 mg (adults) two consecutive days per week for at least 3 mon | 12 weeks | Positive | 40 |
Лучшее время приёма: With a fat-containing meal for optimal absorption
Safety & Side Effects
Зарегистрированные побочные эффекты
- ⚠ Hypercalcemia at very high doses (nausea, vomiting, weakness)
- ⚠ Kidney stones with excessive long-term use
- ⚠ Constipation
- ⚠ Metallic taste
Известные взаимодействия
- ● Thiazide diuretics (may increase risk of hypercalcemia)
- ● Corticosteroids (reduce vitamin D absorption and metabolism)
- ● Orlistat and cholestyramine (reduce fat-soluble vitamin absorption)
Допустимый верхний уровень потребления: 4,000 IU/day
Всегда консультируйтесь с врачом перед началом приёма любых добавок.Всегда консультируйтесь с лечащим врачом перед началом приёма любой добавки.
Frequently Asked Questions
Does Витамин D help with Alopecia Areata?
How much Витамин D should I take for Alopecia Areata?
Are there side effects of Витамин D?
How strong is the evidence for Витамин D and Alopecia Areata?
Related Evidence
Другие ингредиенты для Alopecia Areata
Витамин D для других состояний
References
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